A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 10- to 30-Year-Old Healthy Adolescents and Adults

Active, not recruiting · Phase 1, Phase 2 · NCT05164094

Conditions: Epstein-Barr Virus Infection

Research payments reported, 2025: $12.3M
U.S. investigators named: 64
Sites paid: 54
Planned or actual enrollment: 867

About the trial

Sponsor: ModernaTX, Inc.
Tested: mRNA-1189 (biological), Placebo (biological)
Dates: Started 2021-12-28; completion 2027-08-18
Results posted: Not yet

The main objective of Part A of this trial is to evaluate the safety and reactogenicity of mRNA-1189 in 18- to 30-year-old healthy adults, the main objective of Part B is to evaluate the safety and reactogenicity of mRNA-1189 in 12- to \<18-year-old healthy EBV-seronegative adolescents, and the main objective of Part C is to evaluate the safety and reactogenicity of mRNA-1189 in 10- to 21-year-old healthy adolescents and adults.

From ClinicalTrials.gov, last updated 2026-05-06. Full record, eligibility and contacts (opens in a new tab)

Industry funding

ModernaTX, Inc. reported $12.3M in research payments for this study in 2025 (848 payments).

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

Velocity Clinical Research Inc $1.9M
Clinical Research PArtners $1.1M
Smart Cures Clinical Research $931,058
Dr Shelly David Senders MD $844,319
California Research Foundation $807,968
Medical Affiliated Research Center Inc $712,213
Quality Clinical Research Inc $507,373
Johnson County Clin-Trials $504,381
Dynamed Clinical Research LP $414,487
Tanner Clinic $412,542
Marwah Investments Corporation $404,246
Cedar Health Research LLC $371,651
Qcare Site Services Inc $291,548
Helios Cr Inc $271,415
Cra Headlands LLC $244,213
Center for Clinical Trials LLC $242,485
Peninsula Headlands LLC $220,358
Alliance for Multispecialty Research LLC $218,345
Health Research of Hampton Road Inc $207,771
Victoria Clinical Research Group $199,390
Jacksonville Center for Clinical Research $180,963
Qcare Site Services $174,079
Meridian Clinical Research LLC $141,362
Sundance Clinical Research LLC $115,034
Michael W Simon MD Psc $87,494
Great Lakes Research Institute $86,986
Lucas Research Inc $86,194
Eximia Research Acquisition Holding LLC $81,431
Artemis Headlands LLC $77,587
Tekton Research LLC $74,354
Clinical Research Institute Inc $67,206
Cra Headlands LLC DBA Clinical $45,135
Medical Affiliated Research $38,749
Alliance for Multispeciality Research, LLC $33,685
Memorial Research Medical Clinic $31,137
Fomat Medical Research Inc $25,335
Research Centers of America $22,690
Lsb Research Group LLC $20,296
Health Research of Hampton $16,153
Cenexel Iresearch LLC $13,083
Enso Mb LLC D B A Victoria Clinical Research Group $11,779
Dynamed Chicago LLC $10,883
Lynn Health Science Institute $10,308
University of Massachusetts Medical School $9,621
Memorial Research Medical Clinic DBA Orange County Research Center $8,819
Coastal Pediatric Research $6,998
Research Centers of America LLC $5,636
Coastal Carolina Research Center $4,508
Coastal Pediatric Research. $4,138
Conduct Clinical Trials $3,400
Dynamed Detroit LLC $1,864
Charlottesville Medical Research Center LLC $1,350
University of Massachusetts $1,138
Care Access Research LLC $100

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.

At a glance

About the trial

Industry funding

U.S. investigators named on this study

Sites paid to run it