PERSEVERE- A Trial to Evaluate AMDS in Acute DeBakey Type I Dissection
Active, not recruiting · Not applicable · NCT05174767
Conditions: Acute Aortic Dissection
At a glance
- Research payments reported, 2025
- $365,320
- U.S. investigators named
- 17
- Sites paid
- 19
- Planned or actual enrollment
- 115
About the trial
- Sponsor
- Artivion Inc. (with Syneos Health)
- Tested
- AMDS (device)
- Dates
- Started 2022-05-27; completion 2029-12-06
- Results posted
- Not yet
Prospective, non-randomized, multicenter clinical investigation to assess the safety and effectiveness of AMDS in the treatment of patients with acute DeBakey type I dissection, with evidence of malperfusion, through open surgical repair.
From ClinicalTrials.gov, last updated 2025-01-15. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Artivion, Inc. reported $365,320 in research payments for this study in 2025 (53 payments).
Products named: Amds-Ascyrus Medical
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Kyle Eudailey Cardiothoracic Surgery · Birmingham, AL
- Thomas Reece, MD Cardiothoracic Surgery · Aurora, CO
- Mohiuddin Cheema, M.D. Vascular Surgery · Hartford, CT
- Eric I. Jeng, M.D. Cardiothoracic Surgery · Gainesville, FL
- Bradley G. Leshnower, MD Cardiothoracic Surgery · Atlanta, GA
- S. Christopher Malaisrie, M.D. Cardiothoracic Surgery · Chicago, IL
- Shinichi Fukuhara, M.D. Cardiothoracic Surgery · Ann Arbor, MI
- Puja Kachroo, MD Cardiothoracic Surgery · Saint Louis, MO
- Ibrahim Sultan, M.D. Cardiothoracic Surgery · Cherry Hill, NJ
- Hiroo Takayama, MD Cardiothoracic Surgery · New York, NY
- Castigliano M. Bhamidipati, DO, PHD, MSC Cardiothoracic Surgery · Portland, OR
- Joshua C. Grimm, MD Cardiothoracic Surgery · Philadelphia, PA
- Arminder S. Jassar, MD General Surgery · Philadelphia, PA
- Basel Ramlawi, M.D. Cardiothoracic Surgery · Wynnewood, PA
- Sanford M. Zeigler, MD Cardiothoracic Surgery · Charleston, SC
- William Brinkman, MD Cardiothoracic Surgery · Plano, TX
- Marc R. Moon, MD Cardiothoracic Surgery · Houston, TX
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Baylor Scott and White Research Institute $120,000
- Northwestern University $61,038
- University of Michigan Health System, MI $38,122
- Ohsu Hospital and Clinics, OR $25,563
- University of Colorado Denver $20,792
- Trustees of Columbia Univ| City Of $13,095
- Emory University Hospital, GA $12,532
- Musc Medical Center, SC $11,493
- Massachusetts General Hospital, MA $10,905
- Washington University $8,180
- University of Florida Contrct Grant $8,164
- Bryn Mawr Rehabilitation Hospital $7,923
- University of Alabama Hospital, AL $7,180
- Baylor Research Institute $5,000
- Trustees of Columbia Univ City Of $3,641
- Univ of Pittsburgh Physicians Clini $3,458
- Hartford Hospital, CT $2,980
- Baylor College of Medicine $2,768
- Dell Children's Medical Center, TX $2,488
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.