Trial of Sibeprenlimab in the Treatment of A Nephropathy (IgAN)
Active, not recruiting · Phase 3 · NCT05248646
Conditions: Immunoglobulin A Nephropathy
At a glance
- Research payments reported, 2025
- $986,657
- U.S. investigators named
- 40
- Sites paid
- 40
- Planned or actual enrollment
- 530
About the trial
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
- Tested
- Sibeprenlimab 400 mg (drug), Placebo (drug)
- Dates
- Started 2022-03-15; completion 2027-01-19
- Results posted
- Not yet
To Evaluate the Efficacy and Safety of Sibeprenlimab Administered Subcutaneously in Subjects with Primary Immunoglobulin A Nephropathy
From ClinicalTrials.gov, last updated 2026-07-14. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Otsuka Pharmaceutical Development & Commercialization, Inc. reported $986,657 in research payments for this study in 2025 (55 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Dana Rizk Nephrology (Kidney) · Birmingham, AL
- Luis A. Juncos, M.D. Nephrology (Kidney) · Little Rock, AR
- Leslie F. Thomas, M.D. Nephrology (Kidney) · Phoenix, AZ
- Billy T. Hour, M.D. Hospitalist · Mission Hills, CA
- Raymond K. Hsu, M.D. Nephrology (Kidney) · San Francisco, CA
- Aamir Z. Jamal, M.D. Nephrology (Kidney) · San Dimas, CA
- Richard A. Lafayette, M.D. Nephrology (Kidney) · Stanford, CA
- Sayna Norouzi, M.D. Nephrology (Kidney) · Loma Linda, CA
- John J. Sim, MD Nephrology (Kidney) · Los Angeles, CA
- Laura A. Kooienga, MD Nephrology (Kidney) · Denver, CO
- Nabeel Aslam, MD Nephrology (Kidney) · Jacksonville, FL
- Edouard R. Martin, M.D. Nephrology (Kidney) · Lauderdale Lakes, FL
- Elizabeth T. Nguyen, M.D. Nephrology (Kidney) · Atlanta, GA
- James A. Tumlin, M.D. Nephrology (Kidney) · Lawrenceville, GA
- Ashar Luqman, M.D. Nephrology (Kidney) · Sioux City, IA
- Lama Noureddine, M.D. Nephrology (Kidney) · Iowa City, IA
- Dennis L. Ross, M.D. Specialist · Wichita, KS
- Juan Carlos Q. Velez, MD Nephrology (Kidney) · New Orleans, LA
- Saif A. Alenizi, M.D., M.P.H. Nephrology (Kidney) · Boston, MA
- Lesley A. Inker, MD Nephrology (Kidney) · Boston, MA
- Kenneth M. Ralto, M.D. Nephrology (Kidney) · Worcester, MA
- Meghan E. Sise, M.D. Nephrology (Kidney) · Boston, MA
- Jeffrey H. William, M.D. Nephrology (Kidney) · Boston, MA
- Preeti Chandra, MD Nephrology (Kidney) · Baltimore, MD
- Joel M. Topf, MD Nephrology (Kidney) · Roseville, MI
- Ladan Zand, MD Nephrology (Kidney) · Rochester, MN
- Sahar Koubar, MD Internal Medicine · Durham, NC
- Prasanth Ravipati, M.D. Nephrology (Kidney) · Omaha, NE
- Mark Vishnepolsky, M.D. Nephrology (Kidney) · Las Vegas, NV
- Anjali Acharya Internal Medicine · Bronx, NY
- Kenar D. Jhaveri, M.D Nephrology (Kidney) · Great Neck, NY
- Ahmad Anjak, MD Nephrology (Kidney) · Cincinnati, OH
- Ankur Shah, M.D. Nephrology (Kidney) · Riverside, RI
- Judith A. Betts, MD Nephrology (Kidney) · Austin, TX
- Rahul Pandey, M.D. Nephrology (Kidney) · Houston, TX
- Kumar Sharma, M.D Nephrology (Kidney) · San Antonio, TX
- Biruh Workeneh, MD Nephrology (Kidney) · Houston, TX
- Jingyin Yan, M.D., PH.D. Nephrology (Kidney) · Webster, TX
- Ashraf El-meanawy, MD, PH.D, MS Nephrology (Kidney) · Milwaukee, WI
- Tripti Singh, MD Nephrology (Kidney) · Fitchburg, WI
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Loma Linda University Health $133,588
- Denver Nephrologists PC $111,295
- Dunes Clinical Research LLC $92,951
- University of Alabama Hospital, AL $63,208
- The Board of Trustees of the Leland Stanford Junior University $53,275
- Southern California Permanente Medical Group $52,482
- Unehealth $43,078
- Brigham and Women's Hospital, MA $39,371
- $37,725
- University of Massachusetts $34,523
- Fides Clinical Research LLC $34,375
- Mayo Clinic Hospital, AZ $29,992
- Prolato Research LLC $27,607
- St Clair Nephrology Research LLC $25,516
- UCSF Langley Porter Psychiatric Hospital and Clinics, CA $23,033
- Amicis Research Center $19,400
- Baylor College of Medicine $15,595
- Massachusetts General Hospital, MA $13,434
- Beth Israel Deaconess Medical Center, MA $12,500
- Tufts Medical Center, MA $12,363
- University of Cincinnati $12,175
- University of Texas Health Science Center at San Antonio $11,065
- The Feinstein Institutes for Medical Research $10,702
- South Florida Research Institute $7,457
- University of Iowa Hospital & Clinics, IA $6,606
- Kansas Nephrology Research Institute LLC $6,346
- Ochsner Medical Center Acute, LA $6,028
- Board of Regents of the University of Wisconsin System $5,760
- Pioneer Research Solutions Inc $5,746
- University of Maryland Baltimore $5,740
- Regents of the University of Minnesota $5,734
- Georgia Nephrology LLC $5,604
- Mayo Clinic College of Medicine and Science $3,950
- Jacobi Medical Center, NY $3,626
- Cussimanio Research Group LLC $3,000
- Total Renal Research Inc $2,873
- Rhode Island Hospital, RI $2,710
- North America Research Institute $2,665
- Mayo Clinic $2,030
- Medical College of Wisconsin PArkinsons Program $1,030
- University of Arkansas Medical Sciences, AR $500
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.