HEAL-IST IDE Trial
Active, not recruiting · Not applicable · NCT05280093
Conditions: Inappropriate Sinus Tachycardia
At a glance
- Research payments reported, 2025
- $366,679
- U.S. investigators named
- 23
- Sites paid
- 20
- Planned or actual enrollment
- 100
About the trial
- Sponsor
- AtriCure, Inc.
- Tested
- AtriCure ISOLATOR Synergy Surgical Ablation System (device)
- Dates
- Started 2022-05-31; completion 2028-02
- Results posted
- Not yet
Inappropriate Sinus Tachycardia (IST) is a prevalent and debilitating condition in otherwise healthy younger patients, resulting in significant loss of quality of life, lacking effective treatment options or systematic clinical evidence to support a therapy. The primary objective of this clinical trial is to evaluate the safety and effectiveness of a hybrid sinus node sparing ablation procedure for the treatment of symptomatic drug refractory or drug intolerant IST.
From ClinicalTrials.gov, last updated 2026-11-05. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Atricure, Inc. reported $366,679 in research payments for this study in 2025 (148 payments).
Products named: Isolator Surgical Ablation System
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Devi G. Nair, MD Cardiac Electrophysiology · Jonesboro, AR
- Chad R. Brodt, MD Cardiac Electrophysiology · East Palo Alto, CA
- Joshua S. Chung, M.D. Cardiothoracic Surgery · West Hollywood, CA
- Anson M. Lee, M.D. Cardiothoracic Surgery · Palo Alto, CA
- Margot E. Vloka, M.D. Cardiac Electrophysiology · Aurora, CO
- Joseph J. Tiano, M.D. Cardiac Electrophysiology · Trumbull, CT
- Christian Shults, MD General Surgery · Washington, DC
- Thomas M. Beaver, MD Cardiothoracic Surgery · Gainesville, FL
- Steven J. Hoff, M.D. Cardiothoracic Surgery · Miami, FL
- Kevin J. Makati, MD Cardiology · Lutz, FL
- Chadwick W. Stouffer, MD Cardiothoracic Surgery · Jacksonville, FL
- Paul A. Vesco SR., MD Cardiothoracic Surgery · Sarasota, FL
- David W. Newton, MD Cardiac Electrophysiology · Savannah, GA
- Dhanunjaya Lakkireddy, MD Cardiac Electrophysiology · Kansas City, KS
- Ammar M. Killu, MBBS Cardiology · Rochester, MN
- Gaurang D. Gandhi, MD FACC Cardiac Electrophysiology · Cincinnati, OH
- John M. Smith, M.D. Cardiothoracic Surgery · Cincinnati, OH
- Sean P. Whalen, M.D. Cardiac Electrophysiology · Nashville, TN
- Andrea Natale, MD Cardiac Electrophysiology · Austin, TX
- Michael Cutler, DO Cardiac Electrophysiology · Murray, UT
- John R. Doty, MD Cardiothoracic Surgery · Murray, UT
- Vigneshwar Kasirajan, MD Cardiothoracic Surgery · Richmond, VA
- Eric Lehr, M.D., PHD Cardiothoracic Surgery · Seattle, WA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Wcg Clinical Inc DBA Wcg Irb LLC $108,596
- Ihc Health Services Inc $51,648
- Loma Linda University Health $31,010
- UCSF Health St. Mary's Hospital, CA $28,070
- Texas Cardiac Arrhythmia Research Foundation $26,020
- Kansas City Cardiac Arrhythmia Research $22,685
- Trihealth Inc $21,952
- Board of Trustees of Leland Stanford Junior University $18,731
- Swedish Medical Center, WA $13,395
- Virgina Commonwealth University $8,351
- University of Florida Board of Trustees $6,746
- The Lindner Center for Research and Education at Christ Hospital $6,263
- Baycare Health System Inc $4,500
- University of Florida $4,285
- Mayo Clinic $3,855
- Wake Forest University Health Sciences $3,535
- Sarasota Memorial Hospital, FL $3,434
- Hartford Hospital, CT $2,184
- Saint Alphonsus Regional Medical Center, ID $737
- Savannah Health Services LLC DBA Memorial Health University Med $685
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.