Study to Assess the Effects of PTC857 Treatment in Participants With Amyotrophic Lateral Sclerosis ALS
Terminated · Phase 2 · NCT05349721
Conditions: Amyotrophic Lateral Sclerosis
At a glance
- Research payments reported, 2025
- $284,002
- U.S. investigators named
- 13
- Sites paid
- 13
- Planned or actual enrollment
- 336
About the trial
- Sponsor
- PTC Therapeutics
- Tested
- PTC857 (drug), Placebo (drug)
- Dates
- Started 2022-05-15; completion 2025-01-30
- Results posted
- Yes
This study will assess the efficacy and safety of PTC857 treatment in participants diagnosed with ALS.
From ClinicalTrials.gov, last updated 2025-08-01. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Ptc Therapeutics, Inc. reported $284,002 in research payments for this study in 2025 (47 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Namita Goyal, M.D. Physical Medicine & Rehabilitation (PM&R) · Orange, CA
- Jonathan Katz, M.D. Neurology · San Francisco, CA
- Gustavo J. Alameda, MD Neurology · Fort Lauderdale, FL
- Benjamin Barnes, MD Osteopathic Manipulative Medicine · Augusta, GA
- Omar Jawdat, MD Neurology · Kansas City, KS
- Ximena Arcila-londono, M.D. Neurology · Detroit, MI
- Leo F. Mccluskey, MD Neurology · Charlotte, NC
- Joseph Americo M. Fernandes JR., MD Neurology · Omaha, NE
- Gary L. Pattee, M.D. Neurology · Lincoln, NE
- Nicholas T. Olney, M.D. Neurology · Portland, OR
- Terry D. Heiman-patterson, MD Neurology · Philadelphia, PA
- Yessar M. Hussain, M.D. Physical Medicine & Rehabilitation (PM&R) · Austin, TX
- Aziz Shaibani, MD Neurology · Houston, TX
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- National Neuromuscular Research Institute PLLC $72,443
- California PAcific Medical Center- Van Ness Campus, CA $38,370
- Unehealth $36,215
- Uci Health-Orange, CA $34,852
- Augusta University Research Institute Inc $26,436
- Nerve and Muscle Center of Texas $26,385
- Kumc Research Institute Inc $13,526
- Gsr Enterprises Inc $9,769
- Temple University - of the Commonwealth System of Higher Education $8,160
- Wake Forest University Health Sciences $6,210
- $3,800
- Providence Portland Medical Center, OR $3,700
- Henry Ford Health Hospital, MI $3,500
- Holy Cross Hospital, FL $638
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.