An Open-label Extension Study to Evaluate Long-term Efficacy and Safety of Odevixibat in Children With Biliary Atresia
Active, not recruiting · Phase 3 · NCT05426733
Conditions: Biliary Atresia
At a glance
- Research payments reported, 2025
- $739,521
- U.S. investigators named
- 20
- Sites paid
- 20
- Planned or actual enrollment
- 180
About the trial
- Sponsor
- Albireo, an Ipsen Company
- Tested
- Odevixibat (drug)
- Dates
- Started 2022-07-05; completion 2026-10-28
- Results posted
- Not yet
An Open-label Extension Study to Evaluate Long-term Efficacy and Safety of Odevixibat (A4250) in Children with Biliary Atresia
From ClinicalTrials.gov, last updated 2026-10-23. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Albireo Pharma, Inc. reported $739,521 in research payments for this study in 2025 (244 payments).
Products named: Bylvay
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Laura E. Bauman, M.D. Pediatric Gastroenterology · San Diego, CA
- Rohit Kohli, MBBS, MS Pediatric Gastroenterology · Los Angeles, CA
- Amrita Narang, MD Pediatric Gastroenterology · Palo Alto, CA
- Shikha Sundaram, MD Pediatric Gastroenterology · Aurora, CO
- Adebowale A. Adeyemi, MD Pediatric Gastroenterology · Wilmington, DE
- Jennifer Garcia, MD Pediatric Gastroenterology · Miami, FL
- Reuven Zev Cohen, MD Pediatric Gastroenterology · Atlanta, GA
- Alyssa A. Kriegermeier, M.D. Pediatric Gastroenterology · Chicago, IL
- Eugenia P. Molleston, MD Pediatric Gastroenterology · Indianapolis, IN
- Andrew J. Wehrman, M.D. Pediatric Gastroenterology · Boston, MA
- Maclovio J. Lopez, MD, PHD Pediatric Gastroenterology · Ann Arbor, MI
- Victoria Shakhin, M.D. Pediatric Gastroenterology · Ann Arbor, MI
- Ryan T. Fischer, MD Pediatric Gastroenterology · Kansas City, MO
- Janis M. Stoll, MD Pediatric Gastroenterology · Saint Louis, MO
- Amanda L. Cantor, MD Pediatric Gastroenterology · New York, NY
- Nadia Ovchinsky Pediatric Gastroenterology · New York, NY
- Michael E. Rogers, D.O. Pediatric Gastroenterology · Cincinnati, OH
- Kathleen M. Loomes, M.D. Pediatric Gastroenterology · Philadelphia, PA
- Amal A. Aqul, MD Pediatric Gastroenterology · Dallas, TX
- Evelyn K. Hsu, M.D. Pediatric Gastroenterology · Seattle, WA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Biomedical Research Alliance of New York LLC $83,304
- University of Michigan Health System, MI $82,736
- Children's Hospital Colorado, CO $74,698
- Cincinnati Children's Hospital Medical Center, OH $62,743
- Boston Children's Hospital, MA $61,028
- Regents of the University of California at San Diego in La Jolla, California $40,884
- Children's Hospital of Philadelphia, PA $39,244
- The Children's Mercy Hospital, MO $38,671
- Ann & Robert H Lurie Childrens Hospital of Chicago, IL $33,250
- Washington University School of Medicine $31,157
- Stanford University $27,993
- Childrens Healthcare of Atlanta Inc $22,117
- The Trustees of Columbia University in The City of New York $21,699
- $21,495
- The Trustees of Indiana University $18,928
- Children's Hosp of Los Angeles, CA $17,290
- Nemours Children's Hospital, Delaware, DE $16,665
- Childrens Healthcare of Atlanta $16,457
- The University of Texas Southwestern Medical Center $15,890
- University of Miami $6,879
- Seattle Children's Hospital, WA $6,393
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.