A Study of Remternetug (LY3372993) in Participants With Alzheimer's Disease (TRAILRUNNER-ALZ 1)
Completed · Phase 3 · NCT05463731
Conditions: Alzheimer's Disease
At a glance
- Research payments reported, 2025
- $11.7M
- U.S. investigators named
- 67
- Sites paid
- 74
- Planned or actual enrollment
- 1,667
About the trial
- Sponsor
- Eli Lilly and Company
- Tested
- Remternetug (IV) (drug), Remternetug (SC) (drug), Placebo (drug)
- Dates
- Started 2022-08-01; completion 2026-05-12
- Results posted
- Not yet
The reason for this study is to collect safety and efficacy information regarding the study drug remternetug in participants with early symptomatic Alzheimer's disease (AD).
From ClinicalTrials.gov, last updated 2026-05-22. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Eli Lilly and Company reported $11.7M in research payments for this study in 2025 (134 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Hemant K. Pandey, MD Neurology · Chandler, AZ
- Donald L. Anderson, M.D. Psychiatry · Banning, CA
- Leon Barkodar, M.D. Neurology · West Hills, CA
- Perminder Bhatia, MD Neurology · Fresno, CA
- Clifford R. Feldman, M.D, J.D., M.F.S. Psychiatry · Tarzana, CA
- Benjamin M. Frishberg, M.D. Neurology · Carlsbad, CA
- Elly R. Lee, MD Psychiatry · Irvine, CA
- Alison B. Allen, MD Neurology · Basalt, CO
- Paul K. Brownstone, M.D. Clinical Pharmacology · Boulder, CO
- Thomas D. Mcdonald, MD Neurology · Colorado Springs, CO
- Peter J. Mcallister, M.D. Neurology · Fairfield, CT
- David S. Russell, M.D., PH.D. Neurology · New Haven, CT
- Raymond S. Turner, MD,PHD Neurology · Washington, DC
- Malisa Agard, M.D. Internal Medicine · Orlando, FL
- Cathy B. Barnes, MD Family Medicine · New Port Richey, FL
- David M. Bear, D.O. Neurology · Pensacola, FL
- Jorge J. Calle Medina, M.D. Internal Medicine · Palm Springs, FL
- Jonathan S. Cross, MD Neurology · Aventura, FL
- Mark Goldstein, MD Neurology · Atlantis, FL
- Yaneicy Gonzalez Rojas, MD Internal Medicine · Coral Gables, FL
- John Huffaker, ARNP Nurse Practitioners · Venice, FL
- David A. Kirk Family Medicine · Merritt Island, FL
- Brandon Lenox, D.O. Anesthesiology · Maitland, FL
- Andrew M. Lerman, M.D. Neurology · Miami, FL
- John P. Nardandrea JR., MD Family Medicine · Ocala, FL
- Winston R. Ortiz, MD Neurology · Tallahassee, FL
- Paayal K. Patel, M.D Neurology · West Palm Beach, FL
- Edgardo J. Riverarivera, MD Emergency Medicine · Leesburg, FL
- Reinhard E. Rott, MD-MBA General Practice · Temple Terrace, FL
- Julie B. Schwartzbard, MD Neurology · Aventura, FL
- Steven A. Toenjes, MD Neurology · Jacksonville, FL
- Alexander White, MD Family Medicine · Daytona Beach, FL
- Paul K. Winner, D.O. Child Neurology · West Palm Beach, FL
- Sara Dawit, MD Hospitalist · Roswell, GA
- Nicholas J. Goetsch, D.O. Family Medicine · Waterloo, IA
- John H. Scott, M.D. Pulmonology · West Des Moines, IA
- Concetta M. Forchetti, M.D. Neurology · Elk Grove Village, IL
- Jeffrey S. Ross, M.D. Psychiatry · Northbrook, IL
- Katherine J. Willingham, MD Internal Medicine · Topeka, KS
- Jason R. Morris, MD Family Medicine · Lake Charles, LA
- David J. Dibenedetto, M.D. Pain Medicine · Waltham, MA
- Jeffrey A. Norton, M.D. Pain Medicine · Lawrence, MA
- Stephanie B. Rutrick, MD Neurology · Boston, MA
- Siddharth Kaul, MD Neurology · Bridgeton, MO
- Curtis P. Schreiber, MD Neurology · Bolivar, MO
- Mohammad R. Bolouri, MD Neurology · Matthews, NC
- Mary K. Lawrence, MD Endocrinology & Diabetes · Morehead City, NC
- Sanjiv K. Sharma, M.D. Internal Medicine · Toms River, NJ
- Arun Singh, M.D. Emergency Medicine · Toms River, NJ
- Bharat R. Mocherla, MD Nuclear Medicine · Las Vegas, NV
- Richard F. Holub, MD Neurology · Albany, NY
- Ryan S. Drake, DO Neurology · Canton, OH
- Meenakshi C. Patel, MD Geriatric Medicine · Centerville, OH
- Joel Vandersluis, M.D. Neurology · Dayton, OH
- Michael S. Mega, MD, PHD Neurology · Portland, OR
- Stephen E. Litman, MD Internal Medicine · Dresher, PA
- John A. Stoukides, MD Geriatric Medicine · East Providence, RI
- Oleksandra Dryn, M.D Neurology · Cordova, TN
- Diana R. Kerwin, MD Geriatric Medicine · Dallas, TX
- Alka Khera Neurology · Dallas, TX
- Elizabeth L. Peckham, D.O. Neurology · Round Rock, TX
- Paul E. Schulz, M.D. Neurology · Houston, TX
- Kandasami Senthilkumar, M.D. Neurology · Beaumont, TX
- Duc Tran, MD Neurology · Dallas, TX
- Michelle D. Welch, MD Endocrinology & Diabetes · Shavano Park, TX
- Sabrina A. Benjamin, MD Internal Medicine · Olympia, WA
- Arifulla -. Khan, MD Psychiatry · Bellevue, WA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Optimus U $836,089
- Charter Research LLC $752,710
- Adams Clinical Inc $677,167
- Erg Holding Co LLC DBA St Louis Clinical Trials LLC $668,828
- Care Access Research LLC $626,676
- Visionary Investigators Network $600,580
- Northwest Clinical Research Center $521,792
- University of Texas Health $458,945
- Progressive Medical Concepts LLC $442,029
- Neurology Clinic PC $381,231
- Invicro $373,408
- Las Vegas Medical Research LLC $321,711
- Citizens Memorial Hospital District $318,656
- Keystone Clin Studies $298,966
- Suncoast Clinical Research $273,738
- Gadolin Research LLC $271,996
- Emerald Coast Neurology $265,252
- Premier Research Institute $230,183
- K2 Medical Research LLC $226,627
- Irvine Center for Clinical Research Inc $217,562
- Re Cognition Health Corporation $204,333
- National Clinical Research Inc $187,369
- Profound Research LLC $156,059
- Jem Headlands LLC $154,932
- $143,947
- Alpine Clinical Research Center Inc $143,679
- Renstar Inc $128,076
- Elligo Health Research Inc $127,974
- Tandem Intermediate LLC $127,241
- Kerwin Memory Center LLC $109,575
- Neuro PAin Medical Center Inc $96,483
- Neurology Consultants of Dallas PA $92,062
- Conquest Research LLC $88,915
- Cotton Oneil Msd of Stormont Vail Healthcare $84,880
- Alzheimer's Memory Center $83,972
- Advanced Memory Research Institute of Nj PC $81,393
- Jacksonville Center for Clinical Research $80,752
- Neuroscience Research Center LLC $70,098
- Medvadis Research Corp LLC $60,410
- Valley Medical Research $58,630
- Rhode Island Mood and Memory Research $57,015
- Mercyone Waterloo Medical Center, IA $56,457
- Neurologlocal Associates of Albany PC $53,174
- Mdfirst Research Chandler LLC $50,591
- Neurology Diagnostics Inc $49,157
- Carteret Medical Group LLC $47,701
- Consano Clinical Research LLC $45,658
- Amo Corporation of Tallahassee $43,529
- Elizabeth Peckham Do Central Texas Neurology Consultants $37,349
- Finlay Medical Research Corp $37,308
- Universal Research Group LLC $34,116
- Clinical Research Professionals LLC $29,811
- Merritt Island Medical Research LLC $26,598
- Ki Health PArtners LLC $25,506
- Alicia Cabrera $23,419
- Colorado Springs Neurological Associates $17,300
- Alison B Allen MD $16,605
- Pharmacology Research Institute $12,426
- Neural Net Research LLC $8,950
- Neuropsychiatric Associates of Southwest Fl PA $4,692
- Atlanta Center for Medical Research $4,535
- Adams Clinical LLC $4,091
- Great Lakes Clinical Trials $3,500
- Brain Matters Research Inc $3,276
- Alexian Brothers Health System $2,500
- Inland Rheumatology Clinical Trials Inc $2,396
- North County Neurology Associates $2,001
- Jem Research LLC $1,758
- Institute for Neurodegenerative Disorders $1,265
- Anderson Clinical Research $931
- Encore Borland-Groover Clinical $896
- Christiana Hospital, DE $191
- Trustees of Columbia Univ in The City of Ny $182
- Onsite Clinical Solutions LLC $153
- Cenexel Iresearch LLC $6
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.