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Study of Cabozantinib and Nivolumab in Metastatic Castration Resistant Prostate Cancer

Active, not recruiting · Phase 2 · NCT05502315

Conditions: Castration-resistant Prostate Cancer, Metastatic Cancer

At a glance

Research payments reported, 2025
$122,635
U.S. investigators named
4
Sites paid
4
Planned or actual enrollment
47

About the trial

Sponsor
Rana McKay, MD (with Exelixis, Bristol-Myers Squibb)
Tested
Cabozantinib (drug), Nivolumab (drug)
Dates
Started 2023-02-02; completion 2027-11-12
Results posted
Not yet

This is a multicenter, single-arm, two-stage open-label phase 2 study of the combination of cabozantinib + nivolumab in subjects with advanced castration-resistant prostate cancer (CRPC).

From ClinicalTrials.gov, last updated 2026-11-02. Full record, eligibility and contacts (opens in a new tab)

Industry funding

E.r. Squibb & Sons, L.l.c. reported $122,635 in research payments for this study in 2025 (4 payments).

Products named: Opdivo

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • University of Texas Southwestern $49,514
  • Board of Regents of the University of Wisconsin Systems $37,633
  • University of California San Diego $23,545
  • The University of Chicago Kovler Diabetes Center $11,943

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.