A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease
Recruiting · Phase 3 · NCT05509777
Conditions: Crohn's Disease
At a glance
- Research payments reported, 2025
- $200,969
- U.S. investigators named
- 5
- Sites paid
- 5
- Planned or actual enrollment
- 90
About the trial
- Sponsor
- Eli Lilly and Company
- Tested
- Mirikizumab (drug)
- Dates
- Started 2024-03-13; completion 2028-04
- Results posted
- Not yet
Study participants will be screened during the platform study and randomly assigned to receive mirikizumab or another intervention. The purpose of the mirikizumab study is to evaluate efficacy, safety, tolerability, and how well mirikizumab absorbs into the body of pediatric participants with Crohn's disease. Study periods for the intervention-specific appendix (ISA) will be as follows: * A 12-week induction period * A maintenance period from Week 12 to Week 52, and * A safety follow-up period up to 16 weeks. The study will last about 74 weeks and may include up to 19 visits.
From ClinicalTrials.gov, last updated 2026-10-07. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Eli Lilly and Company reported $200,969 in research payments for this study in 2025 (5 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Jeffrey S. Hyams, MD Pediatric Gastroenterology · Hartford, CT
- Subra Kugathasan, MD Pediatric Gastroenterology · Atlanta, GA
- Jeffery D. Lewis, MD Pediatric Gastroenterology · Atlanta, GA
- Joseph Picoraro, MD Pediatric Gastroenterology · New York, NY
- Arthur J. Kastl JR., M.D. Pediatric Gastroenterology · Philadelphia, PA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Childrens Healthcare of Atlanta $139,589
- Childrens Center for Digestive Health Care LLC $32,553
- Children's Hospital of Philadelphia, PA $14,378
- Trustees of Columbia Univ in The City of Ny $7,448
- Connecticut Childrens Medical Center, CT $7,000
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.