Study With Quadrivalent Recombinant Influenza Vaccine (RIV4) in Participants 9 Through 49 Years of Age.
Completed · Phase 3 · NCT05513053
Conditions: Influenza Immunization
At a glance
- Research payments reported, 2025
- $390,992
- U.S. investigators named
- 17
- Sites paid
- 15
- Planned or actual enrollment
- 1,308
About the trial
- Sponsor
- Sanofi Pasteur, a Sanofi Company
- Tested
- Quadrivalent Recombinant influenza vaccine (RIV4) season/2022-2023/NH (biological)
- Dates
- Started 2022-10-27; completion 2023-10-27
- Results posted
- Yes
The purpose of this study was to demonstrate the non-inferiority (NI) of the HAI immune response of RIV4 in participants aged 9 to 17 years vs participants aged 18 to 49 years and to describe the immunogenicity and safety profile of RIV4 in all participants.
From ClinicalTrials.gov, last updated 2025-09-09. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Sanofi Pasteur Inc. reported $390,992 in research payments for this study in 2025 (52 payments).
Products named: Flublok Quadrivalent Northern Hemisphere
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Max H. Hale, MD Pediatrics · Birmingham, AL
- Kevin G. Rouse, M.D. Pediatrics · Jonesboro, AR
- Todd Bertoch, M.D. Anesthesiology · Prescott, AZ
- Donald M. Brandon, M.D. Internal Medicine · San Diego, CA
- Stacy B. Slechta, DO Family Medicine · Newton, KS
- Daniel J. Finn, MD Pediatrics · Bardstown, KY
- Robert Jeanfreau, M.D. Internal Medicine · Metairie, LA
- David J. Ensz, M.D. Family Medicine · South Sioux City, NE
- Brandon J. Essink, M.D. Family Medicine · Creighton, NE
- Jay R. Meyer, MD Emergency Medicine · Lincoln, NE
- Frank Eder, MD Family Medicine · Binghamton, NY
- Suchet R. Patel, MD Family Medicine · Endwell, NY
- Julie S. Shepard, M.D. Pediatrics · Huber Heights, OH
- John B. Etheridge, MD Pediatrics · Port Royal, SC
- Rodrigo Garcia De La Torre Astudillo, M.D. Pediatrics · Charleston, SC
- Abe H. Moskow JR., M.D. Pediatrics · Barnwell, SC
- James T. Peterson, MD OB-GYN (Obstetrics & Gynecology) · Salt Lake City, UT
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Velocity Clinical Research,inc $76,803
- Velocity Clinical Research, Savannah $64,290
- California Research Foundation $43,136
- Meridian Clinical Research Llc $38,603
- Bb Holdings,llc Dba Jean Brown Research $33,197
- Ohio Pediatric Research Association $30,465
- Kentucky Pediatric Research,inc $23,610
- Velocity Clinical Research $17,602
- J Lewis Research,incorporation $16,405
- Alliance for Multispecialty Research,llc $14,000
- The Childrens Clinic of Jonesboro $13,691
- Alabama Clinical Therapeutics Birmingham $8,495
- Rainbow Research Inc at Barnwell Pediatrics PA $7,870
- Coastal Pediatric Research $1,862
- Coastal Carolina Research Center,incorporation $963
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.