A Study of Peresolimab (LY3462817) in Participants With Moderately-to-Severely Active Rheumatoid Arthritis
Terminated · Phase 2 · NCT05516758
Conditions: Rheumatoid Arthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases, Connective Tissue Diseases, Autoimmune Diseases, Immune System Diseases
At a glance
- Research payments reported, 2025
- $673,438
- U.S. investigators named
- 41
- Sites paid
- 31
- Planned or actual enrollment
- 491
About the trial
- Sponsor
- Eli Lilly and Company
- Tested
- Peresolimab (drug), Placebo (drug)
- Dates
- Started 2022-08-31; completion 2025-01-17
- Results posted
- Yes
The main purpose of this study is to assess the safety and efficacy of peresolimab in adult participants with moderately-to-severely active rheumatoid arthritis.
From ClinicalTrials.gov, last updated 2025-12-04. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Eli Lilly and Company reported $673,438 in research payments for this study in 2025 (41 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Jitendra Sharma, M.B.B.S Neurology · Birmingham, AL
- Mona S. Amin, D.O. Rheumatology · Glendale, AZ
- Swati S. Bharadwaj, MD, MPH Rheumatology · Phoenix, AZ
- Joonhee Lim, MD Rheumatology · Gilbert, AZ
- Nehad Soloman, M.D. Rheumatology · Phoenix, AZ
- Maria W. Greenwald, M.D. Specialist · Palm Desert, CA
- Dan T. La, MD Rheumatology · Tujunga, CA
- Samy K. Metyas, MD Rheumatology · Covina, CA
- Shirley W. Pang, M.D. Rheumatology · Fullerton, CA
- Tien I K. Su, M.D. Rheumatology · Whittier, CA
- Christine T. Thai, M.D. Rheumatology · Huntington Beach, CA
- Jude A. Acloque, M.D. Internal Medicine · Boynton Beach, FL
- Elias Halpert, MD Rheumatology · Tamarac, FL
- Shanmugapriya Reddy, MD Rheumatology · Riverview, FL
- Alexander Torres, MD Rheumatology · Avon Park, FL
- Angela R. Crowley, M.D. Rheumatology · Willowbrook, IL
- Manish Jain, M.D. Rheumatology · Chicago, IL
- Enrique A. Mendez, M.D. Rheumatology · Lake Charles, LA
- Ali A. Karrar, M.D. Rheumatology · Grand Blanc, MI
- Jeffrey A. Potts, MD Internal Medicine · Bay City, MI
- Alexandra Hall, MD Internal Medicine · Minneapolis, MN
- David G. True, D.O. Rheumatology · Nixa, MO
- David H. Snow, M.D. Rheumatology · Delco, NC
- Satkirin Khalsa Family Medicine · Albuquerque, NM
- Leroy A. Pacheco, MD Rheumatology · Albuquerque, NM
- David H. Goddard, MD Rheumatology · Brooklyn, NY
- Devora Lichtman, MD Internal Medicine · Cleveland, OH
- Alan Kivitz, MD Rheumatology · Duncansville, PA
- Sonialy Lugo Ruiz, M.D. Rheumatology · Aguadilla, PR
- Carlos A. Pantojas, M.D. Rheumatology · San Juan, PR
- Amarilis J. Perez Rheumatology · Caguas, PR
- Oscar Soto Raices, MD Rheumatology · San Juan, PR
- Karina Vila-rivera, M.D. Rheumatology · San Juan, PR
- Felix O. Berglund, MD Cardiology · Nashville, TN
- Shaikh Ali, MD PA Rheumatology · Tomball, TX
- Laila Hassan, M.D. P.A. Rheumatology · Houston, TX
- Amber Khan, M.D Internal Medicine · Houston, TX
- Sabeen Najam, MD Rheumatology · Baytown, TX
- Qaiser Rehman, MD Rheumatology · Houston, TX
- Christopher C. Wright, MD Rheumatology · Dallas, TX
- Jeff R. Peterson, MD Rheumatology · Bothell, WA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Biovin Enterprises LLC $174,358
- Arizona Arthritis and Rheumatology Research $163,409
- Dynamed Clinical Research LP, DBA Dm Clinical Research $38,658
- Great Lakes Research Group Inc $37,645
- New York University $37,544
- Newport Huntington Medical Group $30,359
- Desert Medical Advances $23,770
- Aa Mrc LLC $18,576
- Encore Medical Research of Boynton Beach LLC $16,345
- Albuquerque Clinical Trials Inc $15,384
- Gcm Medical Group Psc $14,987
- Interspond LLC $13,965
- Accurate Clinical Management LLC $13,470
- Clinvest Research LLC $10,935
- Altoona Center for Clinical Research PC $7,810
- Amarilis Perez $6,950
- Mindful Medical Research $6,571
- Clinical Research of West Florida Inc $5,660
- Accurate Clinical Research Inc $5,370
- Biopharma Informatic Inc Research Center $5,168
- St Jude Heritage Healthcare $4,560
- West Broward Rheumatology Associtaes Inc $3,990
- Sound Clinical Research, LLC $3,862
- Latin Clinical Trial Center Inc $3,300
- Albuquerque Center for Rheumatology $2,500
- Great Lakes Clinical Trials $2,450
- Crowley Core LLC $2,419
- Harac Research $1,259
- Arthritis Northwest PLLC $836
- Cleveland Clinic, OH $728
- Baycare Health System, Inc. $600
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.