An Extension Study to Evaluate the Long-Term Efficacy, Safety and Tolerability of Minzasolmin (UCB0599) in Study Participants With Parkinson's Disease
Terminated · Phase 2 · NCT05543252
Conditions: Parkinson's Disease
At a glance
- Research payments reported, 2025
- $899,812
- U.S. investigators named
- 43
- Sites paid
- 46
- Planned or actual enrollment
- 428
About the trial
- Sponsor
- UCB Biopharma SRL
- Tested
- Minzasolmin (UCB0599) (drug)
- Dates
- Started 2022-08-29; completion 2025-03-25
- Results posted
- Yes
The purpose of the study is to estimate the pharmacodynamic effects of minzasolmin (UCB0599) on brain pathophysiology in Early-start versus Delayed-start participants originally diagnosed with new onset Parkinson's disease.
From ClinicalTrials.gov, last updated 2026-04-02. Full record, eligibility and contacts (opens in a new tab)
Industry funding
UCB SA reported $899,812 in research payments for this study in 2025 (56 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Stephen S. Flitman, M.D. Neurology · Phoenix, AZ
- Perminder Bhatia, MD Neurology · Fresno, CA
- Mark F. Lew, M.D. Neurology · Los Angeles, CA
- Daniel D. Truong, M.D. Neurology · Fountain Valley, CA
- Rajeev Kumar, MD Neurology · Englewood, CO
- Meagen R. Salinas, MD Neurology · Englewood, CO
- Robert Bonwetsch, MD Neurology · Danbury, CT
- Bernardo M. Rodrigues, M.D. Neurology · Farmington, CT
- Eric M. Folkens, MD Family Medicine · Bradenton, FL
- Robert Hauser, MD Neurology · Tampa, FL
- Stuart H. Isaacson, MD Neurology · Boca Raton, FL
- John C. Morgan, MD Neurology · Augusta, GA
- Ann Killoran, MD Neurology · Iowa City, IA
- Rizwan S. Akhtar, MD Neurology · Chicago, IL
- Christopher G. Goetz, MD Neurology · Chicago, IL
- Martha T. Mcgraw, M.D. Neurology · Winfield, IL
- Rajesh Pahwa, M.D. Neurology · Kansas City, KS
- John T. Slevin, MD Neurology · Lexington, KY
- David J. Houghton, MD Child Neurology · New Orleans, LA
- Albert Y. Hung, MD PHD Neurology · Boston, MA
- Kara M. Smith, M.D. Neurology · Boston, MA
- Kelly Mills, M.D. Neurology · Baltimore, MD
- Aaron L. Ellenbogen, D.O. Neurology · Farmington Hills, MI
- Julia C. Johnson, MD Neurology · Saint Paul, MN
- Michael J. Olek, DO Neurology · Henderson, NV
- Thomas Guttuso, MD Neurology · Buffalo, NY
- Carine Maurer, M.D./PH.D. Neurology · Setauket- East Setauket, NY
- Cheryl H. Waters, M.D. Neurology · New York, NY
- Hubert H. Fernandez, MD Neurology · Cleveland, OH
- Steven Gunzler, MD Neurology · South Euclid, OH
- Ariane Park, M.D. Neurology · Gahanna, OH
- Kevin J. Klos, MD Neurosurgery · Tulsa, OK
- Meredith A. Spindler, MD Neurology · Philadelphia, PA
- Vanessa K. Hinson, MD, PHD Neurology · Charleston, SC
- Mark S. Ledoux, MD Neurology · Memphis, TN
- Sarah K. Horn, M.D. Neurology · San Antonio, TX
- Mya C. Schiess, M.D. Neurology · Houston, TX
- Olga Waln, M.D. Neurology · Houston, TX
- Ramsey A. Falconer, M.D. Neurology · Alexandria, VA
- Karen M. Thomas, DO Neurology · Virginia Beach, VA
- James T. Boyd, MD Neurology · Burlington, VT
- Alida F. Griffith, MD Neurology · Kirkland, WA
- Barry K. Vaught, M.D. Neurology · Crab Orchard, WV
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Medical Univ. of S. Carolina $74,007
- UC Irvine Medical Center- Als & Neuromuscular Center $57,542
- Johns Hopkins University $54,000
- Houston Methodist Research Institute $45,966
- Uh Cleveland Medical Center, OH $38,266
- University of Connecticut School of Medicine $27,652
- Neuro PAin Medical Center Inc $27,105
- Parkinson's Disease and Movement Disorders Center of Boca Raton $26,761
- The Ohio State University $24,576
- Veracity Neuroscience, Llc $24,107
- Inova Fairfax Hospital, VA $23,815
- The Movement Disorder Clinic of Oklahoma PLLC $23,729
- Mayo Clinic Arizona $22,760
- Massachusetts General Hospital, MA $22,115
- Arkansas Children's Hospital $21,900
- University of Texas Health Science Center at San Antonio $21,434
- Univ. of Vermont - Fletcher Allen Health Care, VT $20,931
- University of Iowa Hospital & Clinics, IA $20,340
- Nuvance Health $19,509
- Rush University Medical Center, IL $19,178
- Cleveland Clinic, OH $18,070
- Northwestern University $16,423
- Research Foundation of Suny $15,965
- University of Southern California $14,906
- Elligo Health Research Inc $14,885
- Quest Research Institute $14,801
- Sentara Norfolk General Hospital, VA $14,500
- Ku Infectious Disease $13,568
- Bradenton Research Center Inc $13,307
- University of Kentucky Research Foundation $13,068
- University of Massachusetts $12,271
- Central Dupage Hospital Association $11,688
- Cenexel Rocky Mountain $11,589
- Healthpartners Research Foundation $11,000
- Lynn Health Science Institute Inc. $10,772
- Ochsner Medical Center Acute, LA $10,625
- Parkinson's & Movement Disorders Institute $9,690
- Parkinsons Dis and Movement Disorder Institute Inc $9,434
- Ghsu Research Institute, Inc. $8,873
- Nuvance Health Medical Practice Ct, Inc. Associated Neurologists, P.c. - Neurology $8,220
- Xenoscience Inc $7,863
- Hospital of Univ of Pennsylvania, PA $7,214
- Wr Crcn LLC $6,916
- Sentara Albemarle Medical Center $3,251
- Augusta University - Neurology $2,610
- Suny/stony Brook University Hospital, NY $2,610
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.