A Study of mRNA-1647 Cytomegalovirus Vaccine in Healthy Participants 9 to 15 Years of Age and Participants 16 to 25 Years of Age
Completed · Phase 1, Phase 2 · NCT05575492
Conditions: Cytomegalovirus
At a glance
- Research payments reported, 2025
- $6.5M
- U.S. investigators named
- 47
- Sites paid
- 43
- Planned or actual enrollment
- 873
About the trial
- Sponsor
- ModernaTX, Inc.
- Tested
- mRNA-1647 (biological), Placebo (other)
- Dates
- Started 2022-11-07; completion 2026-05-12
- Results posted
- Not yet
The main purpose of study is to evaluate the safety and immunogenicity of different dose levels of mRNA-1647 versus control in healthy cytomegalovirus (CMV)-seronegative and CMV-seropositive female and male participants 9 to 15 years of age. In addition, mRNA-1647 will be evaluated in female participants 16 to 25 years as a comparator cohort.
From ClinicalTrials.gov, last updated 2026-06-04. Full record, eligibility and contacts (opens in a new tab)
Industry funding
ModernaTX, Inc. reported $6.5M in research payments for this study in 2025 (428 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Swetha Geetha Pinninti, M.D Pediatric Infectious Disease · Birmingham, AL
- Todd Bertoch, M.D. Anesthesiology · Prescott, AZ
- Gary K. Boone, M.D. Family Medicine · San Diego, CA
- Charles F. Carpenter, M.D. Preventive Medicine & Public Health · Sacramento, CA
- Jeffrey S. Overcash, MD Emergency Medicine · Chula Vista, CA
- Michael S. Thakor, MD Rheumatology · Fort Collins, CO
- Fadi Chalhoub Geriatric Medicine · Jacksonville, FL
- Mario J. Gonzalez Fernandez, M.D. Internal Medicine · Tampa, FL
- Julian Melamed, M.D. Internal Medicine · Tampa, FL
- Tatyana S. Miroshnikova, M.D. Internal Medicine · Orlando, FL
- Mobeen H. Rathore, M.D. Pediatric Infectious Disease · Jacksonville, FL
- Georges N. Saliba, M.D. P.A. Pediatrics · Miami, FL
- Adebayo K. Akinsola, M.D. Pediatrics · Chamblee, GA
- Kimball A. Johnson, MD Internal Medicine · Atlanta, GA
- Satoshi Kamidani, MD Pediatric Infectious Disease · Atlanta, GA
- Joseph G. Surber, DO Family Medicine · Columbus, GA
- Jeffrey B. Baker, M.D. Family Medicine · Idaho Falls, ID
- Sherri B. Casey, MD Pediatrics · Covington, LA
- Monika L. Dietrich, MD Pediatric Infectious Disease · New Orleans, LA
- James D. Campbell, MD Pediatric Infectious Disease · Baltimore, MD
- Shishir K. Khetan, MD Internal Medicine · Rockville, MD
- Paul E. Kilgore, M.D. Internal Medicine · Detroit, MI
- Mark R. Schleiss, MD Pediatrics · Minneapolis, MN
- Paul G. Matherne, MD Family Medicine · Gulfport, MS
- Steven R. Bauer Family Medicine · Charlotte, NC
- Jay R. Meyer, MD Emergency Medicine · Lincoln, NE
- Frederick C. Raiser III, DO Emergency Medicine · Omaha, NE
- Sara S. Friedman, M.D. OB-GYN (Obstetrics & Gynecology) · Albuquerque, NM
- Satkirin Khalsa Family Medicine · Albuquerque, NM
- Matthew G. Davis, MD Family Medicine · Rochester, NY
- Frank Eder, MD Family Medicine · Binghamton, NY
- Sharon Nachman, MD Pediatric Infectious Disease · Stony Brook, NY
- Steven E. Cox, D.O. Family Medicine · Norman, OK
- Kyle W. Rickner, M.D Family Medicine · Edmond, OK
- Vladimir Berthaud, M.D. Infectious Disease · Nashville, TN
- Robert C. Bell, M.D. Pediatrics · Beaumont, TX
- John W. Clinton III, M.D. Pediatrics · Port Lavaca, TX
- Warren Conway, MD Family Medicine · San Angelo, TX
- Oscar L. De Valle, M.D. Family Medicine · Houston, TX
- Muhammad Irfan, M.D. Internal Medicine · Tomball, TX
- Richard H. Leggett, DO Family Medicine · Victoria, TX
- Jara K. Mcdonald, M.D. Family Medicine · Marble Falls, TX
- Ivan G. Melendez, M.D. Family Medicine · Mcallen, TX
- Paul K. Pickrell, MD Rheumatology · Austin, TX
- Richard E. Rupp, MD Adolescent Medicine · Galveston, TX
- William Seger, M.D. Family Medicine · Fort Worth, TX
- Sarah I. Smiley, D.O. Hospitalist · Austin, TX
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- West Houston Clinical Research $1.4M
- Qcare Site Services Inc $641,851
- Tekton Research LLC $474,085
- Velocity Clinical Research Inc $469,447
- Crossroads Clinical Research $386,688
- University of Maryland Baltimore $376,193
- Elligo Health Research Inc $369,441
- Prohealth Research Center $309,955
- Regents of the University of Minnesota $269,472
- Moore Clnical Research Inc $217,074
- Jbr Clinical Research LLC $202,416
- Interspond LLC $151,218
- Rochester Clinical Research Inc $132,679
- Victoria Clinical Research Group $106,531
- Palm Harbor Dermatology $101,901
- Paradigm Clinical Rsrch Centers Inc $97,022
- Emory University Hospital, GA $95,918
- Dynamed Clinical Research LP $90,903
- Palm Harbor Dermatology PA Trials Account $58,371
- Clinical Neuroscience Solution $54,137
- Albuquerque Clinical Trials $39,769
- Qcare Site Services $36,763
- Moore Clinical Research Inc $35,735
- Paradigm Clinical Rsrch Center $33,016
- Lynn Health Science Institute $32,225
- The Administrators of the Tulane Educational Fund $30,552
- Administators of Tulane Educational Fund $30,104
- Meridian Clinical Research LLC $29,932
- Enso Mb LLC D B A Victoria Clinical Research Group $26,657
- Regents of the University of University of California at San Diego $25,108
- Administators of Tulane $24,564
- Wayne State University $22,515
- Regents of the University of Minesota $20,936
- Paradigm Clinical Rsrch Center Inc $20,583
- University of Florida $20,539
- University of Texas Medical Branch Galveston, TX $19,903
- Cenexel Iresearch LLC $14,932
- Santos Research Center Corp $12,982
- University of Alabama Hospital, AL $10,763
- Meharry Medical College $6,327
- The Research Foundation Suny $5,650
- Cr Services Acquisition US LLC $2,275
- Brcr Medical Center Inc $500
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.