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A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis

Recruiting · Phase 3 · NCT05862272

Conditions: Uterine Fibroids, Endometriosis

At a glance

Research payments reported, 2025
$4.9M
U.S. investigators named
125
Sites paid
106
Planned or actual enrollment
1,000

About the trial

Sponsor
Sumitomo Pharma Switzerland GmbH
Tested
Relugolix Combination Tablet (drug)
Dates
Started 2023-08-14; completion 2030-09
Results posted
Not yet

The purpose of this clinical trial to characterize changes in bone mineral density during continuous treatment with relugolix combination tablet for up to 48 months (4 years) and 1 year of post-treatment follow-up in premenopausal women with heavy menstrual bleeding associated with uterine leiomyomas (fibroids) or with moderate-to-severe pain associated with endometriosis.

From ClinicalTrials.gov, last updated 2025-08-06. Full record, eligibility and contacts (opens in a new tab)

Industry funding

Sumitomo Pharma America, Inc. reported $4.9M in research payments for this study in 2025 (1,584 payments).

Products named: Orgovyx, Myfembree

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • Alfa Medical Research $551,717
  • Discovery Clinical Trials $337,811
  • Ideal Clinical Research Inc $262,293
  • Ocean Blue Medical Research Center Inc $199,828
  • Tmc Life Research Inc $175,945
  • Eastern Clinical Research $156,278
  • Elligo Health Research Inc $139,347
  • Helios Clinical Research Inc $133,113
  • Interspond LLC $127,740
  • Miami Clinical Research Lllp $105,962
  • Seattle Crc LLC $105,409
  • Sunbelt Research Group LLC $103,436
  • Emerald Coast Obgyn Clinical Research LLC $101,225
  • Lcc Medical Research Institute LLC $99,082
  • Velocity Clinical Research Inc $96,405
  • Amicis Research Center $95,733
  • Pharmaseek LLC $93,672
  • Chattanooga Medical Research LLC $85,451
  • Del Sol Research Management LLC $66,288
  • Clinical Trials Management LLC $61,604
  • Cwrwc $61,461
  • Elias Research Associates LLC $60,967
  • Exordia Medical Research Inc $60,598
  • Praetorian Pharmaceutical Research LLC $57,632
  • Agile Clinical Research Trials LLC $56,410
  • Chandler Clinical Trials LLC $53,047
  • University of California Davis Medical Center, CA $48,782
  • Tidewater Clinical Research Inc $45,808
  • Revive Research Institute Inc $43,578
  • Hospital of Univ of Pennsylvania, PA $42,986
  • Wr Crcn LLC $42,384
  • Emerson Clinical Research Institute Inc $42,171
  • Physicians Research Options LLC $40,873
  • South Florida Wellness & Clinical Research Institute LLC $40,699
  • Advanced Womens Health Institute $40,325
  • Affiliated Clinical Research Inc $40,089
  • Sky Clinical Research Network Group $39,012
  • Long Beach Research Institute $37,467
  • Diagnamics Inc $35,784
  • Ohsu Hospital and Clinics, OR $34,087
  • Southern Clinical Research Associates LLC $33,616
  • Focus Clinical Research Solutions LLC $33,567
  • Suncoast Clinical Research Inc $32,946
  • Cactus Clinical Research Inc $30,928
  • Biocentric LLC $30,322
  • Continental Clinical Solutions LLC $30,147
  • The University of Texas Health $30,137
  • Vida Clinical Research LLC $29,426
  • Unified Women's Clinical Research $29,199
  • Omega Research Orlando LLC $29,029
  • Vital Pharma Research $28,671
  • Genoma Research Group Inc $28,623
  • Fellows Research Alliance Inc $26,477
  • Seven Hills Ob Gyn Associates $26,344
  • Stanford University $26,056
  • Bassem Maximos MD Mph PA $25,955
  • The Jackson Clinic PA $25,952
  • Wayne State University $24,173
  • University Hospitals Cleveland Medical Center $22,978
  • Square One Clinical Research Inc $22,033
  • Intimmedicine Specialists $21,301
  • Clinical Research Prime $19,373
  • Center for Clinical Research LLC $18,064
  • Washington University $17,935
  • Next Innovative Clinical Reseach $15,628
  • Long Beach Clinical Trials Ser $15,445
  • Clinical Associates of Orlando $14,833
  • Physicians Research Group LLC $11,779
  • Health Research of Hampton Road Inc $11,233
  • Quantum Clinical of Dade Count $10,500
  • Washington University School of Medicine $10,353
  • Investigator Research Group LLC $10,310
  • Vip Trials $10,213
  • Clinical Neuroscience Solution $10,103
  • Pivotal Clinical Research and Associates LLC $9,623
  • Altus Clinical Research LLC $9,536
  • Viva Capital Funding LLC $9,065
  • Torrance Clinical Research $8,935
  • Olympia Clinical Trials $8,442
  • Midland Florida Clinical Research Ctr LLC $8,392
  • Johns Hopkins University $7,614
  • University of Texas Medical Branch Galveston, TX $7,339
  • M3 Wake Research Inc $6,618
  • Columbus Regional Research Ins $6,490
  • Great Lakes Research Group Inc $6,400
  • Wasatch Clinical Research LLC $5,393
  • Paramount Research Solutions $4,695
  • R and B Medical Center LLC $4,376
  • Physician Care Clinical Research LLC $4,300
  • Palmetto Clinical Research $4,200
  • Lynn Health Science Institute $3,150
  • Cypress Medical Research Cente $3,085
  • Chicago Clinical Research Institute Inc $2,500
  • Sandhill Research LLC $2,150
  • Leavitt Clinical Research Inc $2,100
  • Comprehensive Clinical Researc $1,991
  • Elite Clinical Studies LLC $1,921
  • Health Research of Hampton Medical Center $1,730
  • Hwc Womens Research Center LLC $1,588
  • Clinical Research Philadelphia LLC $1,500

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.