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A Study to Evaluate the Effect of Cholestyramine on LOXO-783 in Healthy Participants

Completed · Phase 1 · NCT05894928

Conditions: Healthy

At a glance

Research payments reported, 2025
$55,089
U.S. investigators named
2
Sites paid
2
Planned or actual enrollment
21

About the trial

Sponsor
Eli Lilly and Company (with Loxo Oncology, Inc.)
Tested
LOXO-783 (drug), Cholestyramine (drug)
Dates
Started 2023-06-07; completion 2023-07-09
Results posted
Not yet

The main purpose of this study is to conduct blood tests to measure how much LOXO-783 is in the bloodstream and how the body handles and eliminates LOXO-783 when administered alone or in combination with cholestyramine in healthy participants. The study will also evaluate the safety and tolerability of LOXO-783 with and without cholestyramine. Participation could last up to 63 days including screening period.

From ClinicalTrials.gov, last updated 2023-09-26. Full record, eligibility and contacts (opens in a new tab)

Industry funding

Eli Lilly and Company reported $55,089 in research payments for this study in 2025 (2 payments).

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • Covance Clinical Research Unit Inc $27,544
  • Covance Clinical Research LP Dallas $27,544

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.