A Study of mRNA-1018 Pandemic Influenza Candidate Vaccines in Healthy Adults
Completed · Phase 1, Phase 2 · NCT05972174
Conditions: Influenza
At a glance
- Research payments reported, 2025
- $889,740
- U.S. investigators named
- 9
- Sites paid
- 6
- Planned or actual enrollment
- 1,504
About the trial
- Sponsor
- ModernaTX, Inc.
- Tested
- mRNA-1018 for H5N8 (biological), mRNA-1018 for H7N9 (biological), mRNA-1018 for H5 Only (biological), mRNA-1018 for H7 Only (biological), mRNA-1018 for H5 Only-CG (biological)
- Dates
- Started 2023-07-10; completion 2024-07-16
- Results posted
- Not yet
The purpose of this Phase 1/2 study is to generate sufficient safety and immunogenicity data of mRNA-1018 pandemic influenza candidate vaccines in healthy adults ≥18 years of age to enable the initiation of a large Phase 3 trial with one selected vaccine candidate. The study will be conducted in 2 Parts (Part A and Part B) that will enroll and run concurrently. Part A of the study will evaluate 4 vaccine candidates (H5N8, H7N9, H5 only, and H7 only). Part B of the study will evaluate a single vaccine candidate (H5 only-CG).
From ClinicalTrials.gov, last updated 2025-07-16. Full record, eligibility and contacts (opens in a new tab)
Industry funding
ModernaTX, Inc. reported $889,740 in research payments for this study in 2025 (115 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Nelia E. Sanchez-crespo, M.D. Internal Medicine · Hollywood, FL
- Paul S. Bradley, MD Internal Medicine · Savannah, GA
- Carlos A. Fierro, MD General Practice · Kansas City, KS
- Rebecca A. Rivard, D.O. Family Medicine · Roseville, MI
- Jay R. Meyer, MD Emergency Medicine · Lincoln, NE
- David Fried, MD Internal Medicine · East Greenwich, RI
- Lisa R. Holloway, D.O. Family Medicine · Houston, TX
- Earl F. Martin, MD Family Medicine · Tomball, TX
- Katie A. Julien, M.D. Family Medicine · South Jordan, UT
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Dynamed Clinical Research LP $493,612
- Johnson County Clintrials LLC $191,113
- J Lewis Research Inc $79,033
- Research Centers of America LLC $55,702
- Dynamed Detroit LLC $43,328
- Velocity Clinical Research Inc $26,951
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.