A Study to Evaluate the Safety and Immunogenicity of mRNA-1975 and mRNA-1982 Against Lyme Disease in Participants 18 Through 70 Years of Age
Completed · Phase 1, Phase 2 · NCT05975099
Conditions: Lyme Disease
At a glance
- Research payments reported, 2025
- $1.6M
- U.S. investigators named
- 20
- Sites paid
- 19
- Planned or actual enrollment
- 807
About the trial
- Sponsor
- ModernaTX, Inc.
- Tested
- mRNA-1975 (biological), mRNA-1982 (biological), Placebo (biological)
- Dates
- Started 2023-07-26; completion 2025-05-30
- Results posted
- Yes
The purpose of this study is to evaluate the safety and immunogenicity in parallel of heptavalent mRNA-1975 and monovalent mRNA-1982 against Lyme disease in healthy adult participants.
From ClinicalTrials.gov, last updated 2026-07-30. Full record, eligibility and contacts (opens in a new tab)
Industry funding
ModernaTX, Inc. reported $1.6M in research payments for this study in 2025 (259 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- David M. Radin, MD Internal Medicine · Stamford, CT
- Joseph Soufer, M.D. Internal Medicine · Waterbury, CT
- Susann Varano I, MD Geriatric Medicine · New Haven, CT
- Jeffry A. Jacqmein, MD Family Medicine · Jacksonville, FL
- Bruce G. Rankin, D. O. Family Medicine · Deland, FL
- Jon P. Finley, M.D. Sports Medicine · Stockbridge, GA
- Carlos A. Fierro, MD General Practice · Kansas City, KS
- Rajiv Dua, M.D. Family Medicine · Columbia, MD
- Basmah A. Jalil, MD Rheumatology · Bethesda, MD
- Ravi Passi, MD Internal Medicine · Rockville, MD
- Gary D. Berman, M.D. Allergy & Immunology · Minneapolis, MN
- Brandon J. Essink, M.D. Family Medicine · Creighton, NE
- Bertrand P. Cole, DO Addiction Medicine · Somersworth, NH
- Patrick M. Connors, M.D. Internal Medicine · Rochester, NY
- Carl P. Griffin, M.D. Family Medicine · Oklahoma City, OK
- Harris B. Cohen, M.D. Family Medicine · Horsham, PA
- David Fried, MD Internal Medicine · East Greenwich, RI
- Vicki E. Miller, M.D. Family Medicine · Pasadena, TX
- William Seger, M.D. Family Medicine · Fort Worth, TX
- James R. Clark, MD Internal Medicine · Charlottesville, VA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Charlottesville Medical Research Center LLC $351,583
- Dynamed Clinical Research LP $330,630
- Rochester Clinical Research LLC $144,934
- Benchmark Research $142,054
- Johnson County Clintrials LLC $128,769
- Velocity Clinical Research Inc $123,486
- Jacksonville Center for Clinical Research $112,415
- Chase Medical Research LLC $56,906
- Stamford Therapeutics Consortium $43,751
- Cra Headlands LLC $33,984
- Clinical Research Consulting LLC $26,574
- Qcare Site Services Inc $25,651
- Clinical Research Institute Inc $21,130
- Centennial Medical Group PA $17,757
- Activmed Practices and Research LLC $13,985
- Cognitive Clinical Trials LLC $7,272
- Lynn Health Science Institute Inc $4,065
- University Clinical Research Deland LLC $105
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.