Real-World Effectiveness of Dupilumab in Patients With Prurigo Nodularis: An Observational Study
Completed · NCT05991323
Conditions: Prurigo Nodularis
At a glance
- Research payments reported, 2025
- $249,277
- U.S. investigators named
- 25
- Sites paid
- 27
- Planned or actual enrollment
- 110
About the trial
- Sponsor
- Sanofi (with Regeneron Pharmaceuticals)
- Tested
- Dupilumab (drug)
- Dates
- Started 2023-12-12; completion 2026-09-08
- Results posted
- Not yet
This study is a prospective, multinational, observational investigation designed to elucidate the real-world effectiveness and treatment patterns of dupilumab therapy in adult patients diagnosed with prurigo nodularis (PN). The primary objective of this study is to comprehensively characterize the real-world usage of dupilumab for the management of PN. In addition to this, the study aims to achieve several secondary objectives, including a detailed assessment of the medical history, socio-demographic and disease characteristics of dupilumab-treated PN patients, as well as the evaluation of the long-term real-world effectiveness of dupilumab therapy for PN.
From ClinicalTrials.gov, last updated 2026-10-01. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Sanofi US Services Inc. reported $249,277 in research payments for this study in 2025 (126 payments).
Products named: Dupixent
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Lindsay S. Ackerman, MD Dermatology · Phoenix, AZ
- Dathan Hamann, M.D. Dermatology · Phoenix, AZ
- Sunil S. Dhawan, MD Dermatology · Fremont, CA
- Shireen V. Guide, MD Dermatology · Palo Alto, CA
- Katherine B. Lee, M.D., M.A. Dermatology · Laguna Hills, CA
- Tien Q. Nguyen, MD Dermatology · Fountain Valley, CA
- Joshua M. Berlin, MD Dermatology · Boynton Beach, FL
- Brad P. Glick, MD Dermatology · Margate, FL
- Joshua E. Lane, M.D. Mohs Surgery · Columbus, GA
- Scott A. Fretzin, M.D. Dermatology · Indianapolis, IN
- Mark H. Fleischman, MD Mohs Surgery · Leawood, KS
- Kurt Ashack, M.D. Dermatology · Grand Rapids, MI
- Christofer N. Buatti, D.O. Dermatology · Auburn Hills, MI
- Kristi B. Hawley, D.O Dermatology · Caledonia, MI
- Michael Z. Wang, M.D. Dermatology · Rochester, MN
- Amber I. Fresco, M.D. Dermatology · Durham, NC
- Erin X. Barrett, M.D. Dermatology · Fargo, ND
- Victoria G. Farley, M.D. Dermatology · Las Vegas, NV
- Harry Greenberg, MD Dermatology · Las Vegas, NV
- Jorge A. Garcia-zuazaga, M.D. Mohs Surgery · Concord Township, OH
- Lara Wine Lee, M.D. Dermatology · Charleston, SC
- Matthew T. Hoffmann, MD Dermatology · Longview, TX
- Timothy Rodgers Dermatology · Frisco, TX
- Michelle B. Tarbox, MD Dermatology · Lubbock, TX
- Rola M. Gharib, M.D. Dermatology · Morgantown, WV
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Dermatology Skin Cancer Specialists PA $44,392
- Golden State Dermatology Associates Inc $29,336
- The Board of Regents of the University of Nebraska $22,185
- The Derm Institute of West Michigan Plc $20,480
- Duke University Department of Medicine Clinical Res $16,000
- Shireen V Guide MD Inc Mission Dermatology Center $11,147
- Probity Medical Research Corp $10,821
- Private Diagnostic Clinic $9,200
- Center for Dermatology Clinical Research Inc $9,073
- Dawes Fretzin Clinical Research Gro LLC $8,814
- Dermatology Associates of West Michigan $8,000
- $6,719
- Southwest Skin Specialists Llc $6,664
- Cr Services Acquisition Us Llc $6,582
- Las Vegas Dermatology PC $6,261
- Medical University of South Carolina $5,601
- Medical University of South Carolina Health Neurology $5,025
- Quality Clinical Research Inc $3,659
- West Virginia Research Institute PLLC $3,570
- Apex Clinical Research Center Llc $3,000
- Katherine Bao Shian Lee MD A Professional Corporation Halcyon Dermatology $2,238
- Total Vein and Skin, Llc $2,000
- Gsi Clinical Research $2,000
- First Oc Dermatology Research Inc $2,000
- Medical University of South Carolina Att To Elizabeth Gossen $2,000
- North Texas Center for Clinical Research $1,000
- Oakland Hills Dermatology PC $878
- Ttuhsccme $635
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.