A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its Development
Active, not recruiting · NCT06055725
Conditions: Spasticity as Sequela of Stroke
At a glance
- Research payments reported, 2025
- $580,028
- U.S. investigators named
- 18
- Sites paid
- 22
- Planned or actual enrollment
- 1,057
About the trial
- Sponsor
- Ipsen
- Dates
- Started 2023-11-01; completion 2027-11-30
- Results posted
- Not yet
This study will monitor patients during the first year following their stroke. Stroke is a very serious condition where there is a sudden interruption of blood flow in the brain. The main aim of the study will be to find out how many of those who experience their first-ever stroke then go on to develop spasticity that would benefit from treatment with medication. Spasticity is a common post-stroke condition that causes stiff or ridged muscles. The results of this study will provide a standard guideline on the best way to monitor the development of post-stroke spasticity.
From ClinicalTrials.gov, last updated 2026-09-04. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Ipsen Pharma Sas reported $580,028 in research payments for this study in 2025 (210 payments).
Products named: Dysport
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Lucas Restrepo, M.D. Neurology · Los Angeles, CA
- Richard D. Zorowitz, M.D. Physical Medicine & Rehabilitation (PM&R) · Washington, DC
- Anneyd M. Avalos Pena, MD Internal Medicine · Doral, FL
- Thomas C. Marbury, M.D. Nephrology (Kidney) · Orlando, FL
- Vaibhav Shah, MD Neurology · Rockledge, FL
- David J. Lin, MD Neurology · Boston, MA
- Marc Van De Rijn, M.D. Physical Medicine & Rehabilitation (PM&R) · Charlestown, MA
- Joseph E. Burris, MD Physical Medicine & Rehabilitation (PM&R) · Columbia, MO
- James Kult, M.D. Physical Medicine & Rehabilitation (PM&R) · Omaha, NE
- Sonia R. Schneider, MD Physical Medicine & Rehabilitation (PM&R) · Omaha, NE
- Alberto Esquenazi, MD Physical Medicine & Rehabilitation (PM&R) · Philadelphia, PA
- Wuwei Feng, MD MS Neurology · Charleston, SC
- Parneet K. Grewal, M.D. Neurology · Charleston, SC
- Fatma Gul, M.D. Physical Medicine & Rehabilitation (PM&R) · Dallas, TX
- Eric J. Lawitz, M.D. Gastroenterology · San Antonio, TX
- Sean I. Savitz, M.D. Neurology · Houston, TX
- Steven R. Edgley, MD Physical Medicine & Rehabilitation (PM&R) · Salt Lake City, UT
- John R. Mcguire, MD Physical Medicine & Rehabilitation (PM&R) · Milwaukee, WI
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Medstar Health Research Institute $121,480
- University of Utah Hospital and Clinics, UT $62,739
- University of Missouri Health Care, MO $55,174
- Medical University of South Carolina $47,015
- Loma Linda University Health $38,402
- Spaulding Rehabilitation Hospital $32,018
- Duke University $28,732
- The Medical College of Wisconsin Inc $25,608
- American Research Corporation $22,646
- Massachusetts General Hospital, MA $22,065
- The University of Texas Health Science Center at Houston $21,727
- Orlando Clinical Research Center $21,294
- Methodist Health System $19,905
- Ut Southwestern Medical Center $12,596
- Duke University Medical Center $10,879
- The University of Texas Southwestern Medical Center $10,669
- Ut Southwest Medical Center $9,908
- Knight Neurology $5,477
- Madonna Rehab Omaha Ltc Hospital $3,779
- Thomas Jefferson University Hospital $3,215
- Erg Holding Company LLC $3,058
- Medical College of Wisconsin $1,641
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.