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A Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of an Adjuvanted Influenza Vaccine Compared to a Non-adjuvanted Influenza Vaccine in Adults ≥65 Years of Age

Completed · Phase 3 · NCT06087640

Conditions: Influenza, Human

At a glance

Research payments reported, 2025
$37.3M
U.S. investigators named
116
Sites paid
108
Planned or actual enrollment
38,769

About the trial

Sponsor
Seqirus
Tested
aQIV or aTIV (biological), QIV or TIV (biological)
Dates
Started 2023-10-23; completion 2026-06-15
Results posted
Not yet

This Phase 3 study is a randomized, observer-blind study of MF59-adjuvanted influenza vaccine (aQIV or aTIV) compared with a non-adjuvanted influenza vaccine (QIV or TIV) in adults ≥65 years of age. The aim of the study is to evaluate MF59-adjuvanted influenza vaccine compared with non-adjuvanted influenza vaccine in the prevention of reverse transcription-polymerase chain reaction (RT-PCR)-confirmed influenza A and/or B in subjects ≥65 years of age.

From ClinicalTrials.gov, last updated 2026-09-02. Full record, eligibility and contacts (opens in a new tab)

Industry funding

Seqirus USA Inc reported $37.3M in research payments for this study in 2025 (15,245 payments).

Products named: Fluad

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • Velocity Clinical Research, Inc. $10.9M
  • Pharmaseek LLC $4.1M
  • M3 Wake Research, Inc $1.8M
  • Eximia Research LLC $1.8M
  • Global Health Research Center $1.1M
  • Dynamed Clinical Research $913,733
  • 3sync $750,314
  • Marwah Investments Corporation $642,701
  • Paradigm Clinical Research Centers $596,093
  • USA and International Research Inc $595,417
  • Clinical Research Associates $585,347
  • Dm Clinical Research - Chicago $414,743
  • Jacksonville Center for Clinical Research $403,483
  • Tekton Research Inc $402,548
  • Dm Clinical - Phoenix $392,335
  • Quest Research Institute $369,969
  • Qcare Site Services Inc. $366,884
  • Dynamed Washington LLC $363,534
  • Baptist Health Center for Clinical Research $361,684
  • Dm Clinical Research - Southfield $361,365
  • Dm Clinical Research - Brookline $361,347
  • Apex Clinical Research $353,058
  • Dm Clinical Research - New Jersey $340,586
  • Precision Clinical Research Inc $335,808
  • Suncoast Research Associates LLC Dba Sra Trials $334,353
  • Imagine Research $315,019
  • Coastal Carolina Research Center Inc $314,007
  • North Georgia Clinical Research, LLC $309,317
  • Kansas City Research Institute LLC $306,467
  • Clinical Trials of Texas, Inc. $299,595
  • Trial Management Associates LLC - Ern - Ppds $294,610
  • Clinical Research PArtners LLC $294,548
  • Boeson Research $280,387
  • Charlottesville Medical Research Center LLC $280,292
  • Trio Clinical Trials LLC $279,239
  • Nature Coast Clinical Research $274,628
  • Las Vegas Clinical Trials, LLC $257,674
  • Scottsdale Clinical Trials $245,207
  • Chase Medical Research, Llc $245,106
  • Alliance for Multispecialty Research $244,769
  • Activmed Practices and Research LLC $244,362
  • Community Research Management Associates, Inc. $244,063
  • Great Lakes Clinical Trials $233,643
  • Vector Clinical Trials $228,229
  • Asheville Clinical Research $226,743
  • Lynn Health Science Institute $222,627
  • Green Leaf Clinical Trials LLC $222,242
  • Cullman Clinical Trials $220,861
  • Achieve Clinical Research LLC $218,560
  • West Coast Research LLC $216,261
  • Long Beach Research Institute $212,770
  • Clinical Research Consulting $196,549
  • Agile Clinical Research Trials $192,121
  • Innovative Research of West Florida $186,374
  • Research Your Health $183,429
  • Sandhill Research LLC $182,804
  • Lynn Health Science Institute (lhsi) (lynn Institute) - Lynn Institute of the Ozarks $171,849
  • Profound Research $78,794
  • Centricity Research $75,005
  • Avacare Clinical Research Network $19,288
  • Acrc Trials $18,089
  • Long Beach Clinical Trials, LLC $15,638
  • Revival Research Institute $15,256
  • Wr-Global Medical Research, LLC $14,711
  • Sundance Clinical Research $14,252
  • Central Valley Research - Modesto $13,839
  • Wr-Clinsearch, LLC $13,053
  • Wr-Crcn $12,967
  • Wr-Mount Vernon Clinical Research, LLC $12,579
  • Dm Clinical Research - Phoenix $12,555
  • Cti Clinical Trial & Consulting $12,532
  • Albuquerque Clinical Trials, Inc. $11,925
  • Activian Clinical Research, LLC $10,897
  • Suncoast Research Associates, LLC - Pembroke Pines $10,352
  • Eximia Clinical Research Nc, LLC $10,352
  • Nature Coast Clinical Research - Crystal River $10,282
  • Axsendo Clinical Research $8,861
  • Health Awareness Inc $8,792
  • Simedhealth $8,671
  • Meridian Clinical Research $7,692
  • Charleston Clinical Trials $7,628
  • Dm Clinical Research - San Antonio $7,410
  • Dm Clinical Research - Sugarland $6,538
  • Dm Clinical Research - Seattle $6,538
  • Dm Clinical Research - Detroit $6,538
  • Dm Clinical Research - Boston $6,538
  • Bioscope Clinical Research, LLC $6,538
  • Zillan Clinical Research $6,538
  • Monroe Biomedical Research $6,308
  • Achieve Clinical Research $5,993
  • Accel Research $5,993
  • Eximia Research Ga, LLC $5,993
  • Clinical Research Consultants LLC $5,993
  • Leading Edge Research $5,993
  • Eximia Research Ca LLC $5,993
  • Trial Management Associates LLC $5,449
  • Fleming Island Center for Clinical Research $5,449
  • Lynn Institute of Denver $5,231
  • St. Johns Center for Clinical Research $5,231
  • Dm Clinical Research - Martin Diagnostic Clinic $5,231

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.