Dose Ranging Study of Lunsekimig Compared With Placebo-control in Adult Participants With Moderate-to-severe Asthma
Completed · Phase 2 · NCT06102005
Conditions: Asthma
At a glance
- Research payments reported, 2025
- $7.7M
- U.S. investigators named
- 48
- Sites paid
- 45
- Planned or actual enrollment
- 685
About the trial
- Sponsor
- Sanofi
- Tested
- Lunsekimig (drug), Placebo (drug)
- Dates
- Started 2023-10-16; completion 2026-03-11
- Results posted
- Not yet
This is a Phase 2b, global, multicenter, randomized, double-blind, placebo-controlled, parallel group, dose ranging study to assess the efficacy, safety, and tolerability of add-on therapy with SC lunsekimig in adult participants aged 18 to 80 years, (inclusive) with moderate-to-severe asthma.
From ClinicalTrials.gov, last updated 2026-03-17. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Sanofi US Services Inc. reported $7.7M in research payments for this study in 2025 (491 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Michael E. Manning, MD Allergy & Immunology · Scottsdale, AZ
- Ashvin K. Shah, M.D. Sleep Medicine · Yuma, AZ
- Rami S. El-yousef, M.D. Pulmonology · Newhall, CA
- Alan B. Goldsobel, MD Allergy & Immunology · San Jose, CA
- Shawn K. Hassler, M.D. Infectious Disease · San Francisco, CA
- Alberto J. Odio, M.D. Family Medicine · Simi Valley, CA
- David N. Pham, MD Pulmonology · Westminster, CA
- Ricardo A. Tan, MD Allergy & Immunology · Los Angeles, CA
- Robert A. Williams JR., M.D. Family Medicine · Ventura, CA
- James D. Wolfe, MD Allergy & Immunology · San Jose, CA
- Jeffrey S. Rumbyrt, M. D. Allergy & Immunology · Lakewood, CO
- Jaime Avecillas, MD Pulmonology · Miami, FL
- Ivan Carreras, MD Internal Medicine · Hialeah, FL
- Sander Fernandez, M.D. Family Medicine · Miami, FL
- Oscar G. Galvez, MD Nephrology (Kidney) · Miami, FL
- Joel Gonzalez, M.D. Internal Medicine · Homestead, FL
- Jaime Kratz, MD Allergy & Immunology · Port Richey, FL
- Jaynier Moya, MD Internal Medicine · Pembroke Pines, FL
- Agustin Rivas, M.D. General Practice · Miami Springs, FL
- Rafael Ubeda, MD Family Medicine · Lake Worth, FL
- Hugh H. Windom, M.D. Allergy & Immunology · Sarasota, FL
- John J. Trimble III, MD ENT (Otolaryngology) · Acworth, GA
- Kaushik J. Patel, MD Pulmonology · Champaign, IL
- Jibran E. Atwi, MD Allergy & Immunology · Lafayette, LA
- Elliot Israel, MD Pulmonology · Brookline, MA
- Richard A. Bernstein, M.D. Pulmonology · Annapolis, MD
- Njira L. Lugogo, M.D. Pulmonology · Ann Arbor, MI
- Srinivasan Ramanuja, M.D. Allergy & Immunology · Mankato, MN
- William L. Johnson, MD Pediatrics · Saint Louis, MO
- Robert F. Onder, M.D. Allergy & Immunology · Saint Louis, MO
- Walid R. Eltaraboulsi, MD Pulmonology · Charlotte, NC
- Christina C. Kennelly, M.D. Internal Medicine · Charlotte, NC
- Todd Funkhouser, M.D., PH.D Allergy & Immunology · Las Cruces, NM
- Monica Kraft Pulmonology · New York, NY
- Jonathan Weiss, PA Physician Assistants · Middletown, NY
- Syed M. Rehman, MD Allergy & Immunology · Toledo, OH
- Jeremy Cole, MD Sleep Medicine · Edmond, OK
- Sandeep Bansal, MD Pulmonology · Du Bois, PA
- Michael J. Palumbo, M.D. Allergy & Immunology · Pittsburgh, PA
- An H. Pham, MD Pulmonology · Pottstown, PA
- Christian D. Graf, MD Emergency Medicine · Moncks Corner, SC
- Charles A. Thompson, MD Pulmonology · Anderson, SC
- Philip K. Chen, M.D. Family Medicine · Plano, TX
- David Fuentes, MD Allergy & Immunology · Boerne, TX
- Nicola Hanania, MD Pulmonology · Houston, TX
- William C. Howland III, MD Allergy & Immunology · Austin, TX
- Shahrukh A. Kureishy, MD Pulmonology · Mckinney, TX
- Emeka M. Eziri, MD Pulmonology · Princeton, WV
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Ib Miami LLC $1.1M
- Qway Research Llc $810,716
- Clintex Research Group Inc $609,864
- Ok Clinical Research LLC $505,771
- High Quality Research Inc $488,926
- New Access Research and Medical Services Inc $438,718
- Metroplex Pulmonary and Sleep Center $379,854
- Elligo Health Research Inc $379,226
- Deluxe Health Center $340,878
- Pines Care Research Center Llc $294,801
- Crn Clinical Research Network LLC $263,635
- Beautiful Minds Medical Center Llc $218,011
- Allianz Research Institute Co Llc $184,405
- Orion Clinical Research $169,910
- Western States Clinical Research in $142,427
- Javara Inc $124,898
- The Regents of the University of Michigan $124,675
- Brigham and Women's Hospital, MA $103,917
- Midwest Clinical Research Center St Louis $97,936
- Allergy Asthma Associates of Santa Clara Valley A Medical Corp $83,492
- Toledo Institute of Clinical Resear Inc $82,173
- Howland Allergy and Asthma PLLC $71,684
- Sarasota Fl Clinical Research Llc Sarasota Clinical Research $66,216
- Amicis Research Center Llc $64,726
- Baylor College of Medicine $53,570
- Western Sky Medical Research $48,825
- California Allergy and Asthma Medical Group $48,161
- Vast Clinical Research Llc $46,001
- Innovo Research Inc $45,850
- Empirican Prn Inc Circuit Clinical $38,542
- American Carolina Clinical Research $38,212
- Velocity Clinical Research Inc $36,130
- Icahn School of Medicine at Mount Sinai $32,520
- Epimrd Inc Western Sky Medical Research $30,039
- Ricardo Antonio Tan MD Inc $27,772
- Allergy and Clinical Immunology Associates, PC $23,498
- Allergy and Asthma Associates of Santa Clara Valley Research Center $21,850
- Appalachian Clinical Research $20,903
- Allergy and Asthma Associates of Sa Clara Valley Research Center $19,463
- Clinical Trials Management Services, Llc $18,067
- Allergy, Asthma and Immunology Associates, Ltd $13,398
- Studyops Inc $12,630
- Advanced Research Institute New Port Richey $7,700
- Yuma Clinical Trials Llc $7,500
- Clinical Research Associates of Central PA LLC $4,575
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.