Real-World Study of ABBV-951 Subcutaneous Infusion to Assess Change in Disease Activity in Adult Participants With Parkinson's Disease
Active, not recruiting · NCT06107426
Conditions: Parkinson's Disease (PD)
At a glance
- Research payments reported, 2025
- $828,308
- U.S. investigators named
- 25
- Sites paid
- 30
- Planned or actual enrollment
- 427
About the trial
- Sponsor
- AbbVie
- Dates
- Started 2024-01-24; completion 2029-05
- Results posted
- Not yet
Parkinson's disease (PD) is a neurological condition, which affects the brain. PD gets worse over time, but how quickly it progresses varies a lot from person to person. Some symptoms of PD are tremors, stiffness, and slowness of movement. The purpose of this study is to evaluate how effective ABBV-951 is in treating adult participants with advanced PD in real world setting. ABBV-951 (foslevodopa/foscarbidopa) is an approved drug for the treatment of Parkinson's Disease. The main ROSSINI study will have approximately 450 adult participants with PD (300 participants new to ABBV-951, up to 150 participants transitioning from open-label extension study) will be enrolled across approximately …
From ClinicalTrials.gov, last updated 2026-04-27. Full record, eligibility and contacts (opens in a new tab)
Industry funding
AbbVie Inc. reported $828,308 in research payments for this study in 2025 (113 payments).
Products named: Vyalev
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- David Standaert Neurology · Birmingham, AL
- Sara S. Dhanani, M.D Neurology · Sun City, AZ
- Salima L. Brillman, MD Psychiatry · Sunnyvale, CA
- Yasar Torres-yaghi, M.D. Neurology · Washington, DC
- Robert Hauser, MD Neurology · Tampa, FL
- Stuart H. Isaacson, MD Neurology · Boca Raton, FL
- Corneliu Luca, MD Neurology · Miami, FL
- Irene A. Malaty, MD Neurology · Gainesville, FL
- Ramon L. Rodriguez-cruz, MD Neurology · Orlando, FL
- Leonard Verhagen Metman, MD Neurology · Chicago, IL
- Rajesh Pahwa, M.D. Neurology · Kansas City, KS
- David J. Houghton, MD Child Neurology · New Orleans, LA
- Anna D. Hohler, MD Neurology · Brockton, MA
- Kristine Domingo Neurology · Minneapolis, MN
- Deepal P. Shah-zamora, M.D. Neurology · Winston Salem, NC
- Robert C. Wiggins Neurology · Charlotte, NC
- Odinachi N. Oguh, M.D Neurology · Las Vegas, NV
- Ritesh Ramdhani, M.D. Specialist · New York, NY
- Kevin J. Klos, MD Neurosurgery · Tulsa, OK
- Andrew B. Giritharan, MD Neurology · Nashville, TN
- Michael Soileau, MD Neurology · Georgetown, TX
- Eleni O. Vaou, M.D. Neurology · San Antonio, TX
- Paolo M. Moretti, MD Neurology · Salt Lake City, UT
- Pinky Agarwal, MD Neurology · Kirkland, WA
- Jason L. Aldred, M.D. Neurology · Spokane, WA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Inland Northwest Research LLC $131,071
- Parkinson S Disease and Movement $89,049
- University of South Florida $65,324
- University of Kansas Medical Center $51,442
- University of Texas Health Science $43,983
- Northwestern University $41,939
- Georgetown University $35,700
- University of Alabama Hospital, AL $34,558
- Feinstein Institute for $29,580
- Bmc Community Hospital Corp II $29,191
- Novant Health Clinical Research LLC $27,830
- Univ of Florida Board of Trustees $26,044
- Vanderbilt University Medical Center, TN $25,085
- Banner Casa Grande Medical Center, AZ $25,064
- U of Utah Neuropsychiatric Institute $23,919
- Cleveland Clinic, OH $20,996
- University of Miami $18,344
- Regents of the Univ of Minnesota $17,550
- Texas Movement Disorder $16,515
- N1 Research LLC $14,596
- Inland Northwest Research $14,575
- Wake Forest University $12,800
- Parkinson's Disease and M $12,000
- Ochsner Medical Center Acute, LA $10,250
- The Movement Disorder Clinic Of $9,000
- King County Public Hospit DBA Evergreen Health $1,000
- University of Kansas Medi $405
- University of South Flori $250
- Banner - University Medical Center Phoenix, AZ $200
- Novant Health Clinical Re $50
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.