A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy
Active, not recruiting · Phase 4 · NCT06112743
Conditions: Cardiomyopathy, Hypertrophic
At a glance
- Research payments reported, 2025
- $167,352
- U.S. investigators named
- 8
- Sites paid
- 11
- Planned or actual enrollment
- 63
About the trial
- Sponsor
- Bristol-Myers Squibb
- Tested
- Mavacamten (drug)
- Dates
- Started 2024-01-24; completion 2027-06-10
- Results posted
- Not yet
The purpose of this study is to evaluate the mavacamten impact on myocardial structure with cardiac magnetic resonance imaging (CMR) in adult participants with symptomatic obstructive hypertrophic cardiomyopathy (oHCM) \[New York Heart Association (NYHA) Functional Class II or III\].
From ClinicalTrials.gov, last updated 2026-09-16. Full record, eligibility and contacts (opens in a new tab)
Industry funding
E.r. Squibb & Sons, L.l.c. reported $167,352 in research payments for this study in 2025 (12 payments).
Products named: Camzyos
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Florian Rader, MD Cardiology · West Hollywood, CA
- Rahul Loungani, M.D. Heart Failure & Transplant Cardiology · Atlanta, GA
- Jordan B. Strom, MD Cardiology · Boston, MA
- Imran Rashid, MBBS Cardiology · Cleveland, OH
- Albree Tower-rader, MD Internal Medicine · Cleveland, OH
- Victor Farah, MD Cardiology · Pittsburgh, PA
- Sherif Nagueh, M.D. Cardiology · Houston, TX
- Kia Afshar, M.D. Internal Medicine · Murray, UT
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Allegheny-Singer Research Institute (asri) $38,334
- Piedmont Hospital $31,220
- Uh Cleveland Medical Center, OH $25,900
- Houston Methodist Research Institute $24,011
- Cedars-Sinai Medical Center, CA $23,098
- Piedmont Health $17,510
- Massachusetts General Hospital, MA $3,686
- Jordan B Strom, Llc $1,600
- University Hospitals Cleveland Medical Center - 11100 Euclid Avenue $976
- Cedars Sinai Medical Center - 127 San Vicente Boulevard $531
- Intermountain Medical Center, UT $487
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.