ACP-204 in Adults With Alzheimer's Disease Psychosis
Recruiting · Phase 2, Phase 3 · NCT06159673
Conditions: Alzheimer's Disease Psychosis
At a glance
- Research payments reported, 2025
- $4.6M
- U.S. investigators named
- 38
- Sites paid
- 32
- Planned or actual enrollment
- 1,074
About the trial
- Sponsor
- ACADIA Pharmaceuticals Inc.
- Tested
- ACP-204 (drug), Placebo (drug)
- Dates
- Started 2023-11-14; completion 2028-02
- Results posted
- Not yet
This is a master protocol for 3 independent, seamlessly enrolling, multicenter, randomized, double-blind, placebo-controlled, parallel-group studies in patients with ADP * Substudy 1 (Phase 2) will evaluate efficacy and dose response of ACP-204 30 and 60 mg vs placebo. This substudy will be initiated first. * Substudies 2A and 2B (both: Phase 3) will be confirmatory studies of either both doses (ACP-204 30 and 60 mg, respectively) or a single dose from Part 1 vs placebo. Substudies 2A and 2B will be performed independently of each other and will commence after enrollment of Part 1. All 3 substudies will be analyzed independently of each other. Each substudy individually will consist of a …
From ClinicalTrials.gov, last updated 2026-11-05. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Acadia Pharmaceuticals Inc reported $4.6M in research payments for this study in 2025 (1,098 payments).
Products named: Acp-204
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Allan M. Block, M.D. Neurology · Scottsdale, AZ
- Muhammad M. Salim, MD Pulmonology · Chandler, AZ
- Gustavo Alva, M.D. Psychiatry · Orange, CA
- Steven Macina, DO Psychiatry · Huntington Beach, CA
- Elizabeth Zarate-rowell, M.D. Psychiatry · Seal Beach, CA
- Peter J. Mcallister, M.D. Neurology · Fairfield, CT
- Leonardo Alonso, M.D. Psychiatry · Miami, FL
- Emelina A. Arocha, M.D. Psychiatry · Miami, FL
- Jorge Betancourt, MD Psychiatry · Mia, FL
- David Billmeier, MD Family Medicine · Daytona Beach, FL
- Raul E. Carballosa, M.D. Neurology · Boca Raton, FL
- Angel M. Carrasco, M.D. Neurology · Miami, FL
- Kenia Castro, M.D. Psychiatry · Hialeah, FL
- Rusdany Collado Fuentes, MD Neurology · Miami, FL
- Victor Faradji, MD Neurology · Miami, FL
- Christopher A. Fayeghi, D.O. Family Medicine · Miami, FL
- Gil Fernandez-yera, M.D. General Practice · Miami, FL
- Yaneicy Gonzalez Rojas, MD Internal Medicine · Coral Gables, FL
- Meghan M. Harris, M.D. Infectious Disease · Tampa, FL
- Emilio Mantero Atienza, MD Psychiatry · Miami Beach, FL
- Aniel Navarro Marin, M.D. Family Medicine · Miami, FL
- Lissette Selem, PHYSICIAN/MD Psychiatry · Miami Lakes, FL
- Pilar F. Trueba, MD Family Medicine · Doral, FL
- Mohamed K. Ghumra, MD Neurology · Elgin, IL
- Muhammad Afzal Khan, MD Internal Medicine · Rahway, NJ
- Bela Ajtai, MD, PHD Neurology · Amherst, NY
- Randall G. Berliner, MD Neurology · Bronx, NY
- Meenakshi C. Patel, MD Geriatric Medicine · Centerville, OH
- David C. Weisman, M.D. Neurology · Abington, PA
- Kinjal Desai, M.D., MPH Neurology · Webster, TX
- Napoleon B. Higgins, M.D. Psychiatry · Friendswood, TX
- David H. Hunter, M.D. Neurology · Houston, TX
- Jamshid Lotfi, MD Neurology · Houston, TX
- Shahbuddin Mukardamwala, MD Neurology · Houston, TX
- Ankit A. Patel, M.D. Neurology · Katy, TX
- Eddie L. Patton JR., M.D. Neurology · Houston, TX
- Salah U. Qureshi, MD Psychiatry · Friendswood, TX
- Mustafa H. Zaidi, MD Psychiatry · Richmond, TX
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Verus Clinical Research Corp $1.3M
- Reliable Clinical Research LLC $1.1M
- Future Care Solution LLC $549,360
- Homestead Associates in Research Inc $326,678
- Mediclear Medical & Research Center Inc $239,165
- Premier Clinical Research Institute Inc $236,641
- Floridian Neuroscience Institute Inc $163,359
- The University of Texas Health Science Center at Houston $87,095
- Elias Research Associates LLC $83,554
- New Life Medical Research Center Inc $80,765
- National Institute of Clinical Research $80,537
- Wcg Clinical Inc $70,646
- Advanced Clinical Research Network Corp $67,784
- Nayab Goher $43,832
- Prolato Research LLC $39,192
- Scla Management $29,071
- Quantum Clinical of Dade County $25,289
- Cliniverse Research LLC $19,800
- Abington Neurological Associates $18,161
- Orca Trial $17,200
- Advanced Research Center Inc $13,153
- Global Medical Institutes Florida LLC $12,925
- Ki Health PArtners LLC $12,500
- M PAtel $10,498
- Clinical Trial Network LLC $10,296
- Tranquil Clinical and Research Consulting Services $8,332
- Arrow Clinical Trials $8,150
- Visionary Investigators Network $8,118
- Trials Hub $5,900
- Dent Neurosciences Research Center $4,000
- Chandler Clinical Research Trials LLC $4,000
- Pns Clinical Research LLC $2,968
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.