A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer
Recruiting · Phase 3 · NCT06203210
Conditions: Small Cell Lung Cancer
At a glance
- Research payments reported, 2025
- $1.5M
- U.S. investigators named
- 33
- Sites paid
- 38
- Planned or actual enrollment
- 540
About the trial
- Sponsor
- Daiichi Sankyo (with Merck Sharp & Dohme LLC)
- Tested
- Ifinatamab deruxtecan (drug), Topotecan (drug), Amrubicin (drug), Lurbinectedin (drug)
- Dates
- Started 2024-05-21; completion 2029-12-01
- Results posted
- Not yet
This study is designed to compare the efficacy and safety of I-DXd with treatment of physician's choice in participants with relapsed small cell lung cancer (SCLC).
From ClinicalTrials.gov, last updated 2026-08-06. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Daiichi Sankyo Inc. reported $1.5M in research payments for this study in 2025 (1,364 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Eric S. Schaefer, M.D. Hematology & Oncology · Rogers, AR
- Sungwon R. Kyung, M.D. Hematology & Oncology · Los Angeles, CA
- Aaron Lisberg, MD Hematology & Oncology · Santa Monica, CA
- Yung Lyou, M.D., PH.D. Hematology & Oncology · Fullerton, CA
- Claire K. Mulvey, M.D. Hematology & Oncology · San Francisco, CA
- Tarek M. Mekhail, M.D. Hematology & Oncology · Orlando, FL
- Estelamari Rodriguez, MD Hematology & Oncology · Miami, FL
- Vamsidhar Velcheti, MD Hematology & Oncology · Jacksonville, FL
- Ira A. Oliff, MD Hematology & Oncology · Skokie, IL
- Koosha Paydary, MD Hematology & Oncology · Chicago, IL
- Firas B. Badin, M.D. Hematology & Oncology · Lexington, KY
- Jacob M. Sands, MD Hematology & Oncology · Burlington, MA
- Taofeek K. Owonikoko, M.D. Hematology & Oncology · Baltimore, MD
- Deanna G. Teoh, M.D. Gynecologic Oncology · Minneapolis, MN
- Yifan Tu, M.D. Hematology & Oncology · St. Louis, MO
- Omar K. Abughanimeh, MBBS Hematology & Oncology · Omaha, NE
- Konstantin H. Dragnev, MD Hematology & Oncology · Lebanon, NH
- Jatin K. Desani, MD Hematology & Oncology · Manahaukin, NJ
- Bruno S. Fang, MD Hematology & Oncology · East Brunswick, NJ
- James D'olimpio Hematology & Oncology · Lake Success, NY
- Deborah B. Doroshow, M.D., PH.D. Medical Oncology · New York, NY
- Salman Punekar, M.D. Medical Oncology · New York, NY
- Balazs Halmos, MD Hematology & Oncology · Cleveland, OH
- Mitchell Haut, M.D. Hematology & Oncology · Canton, OH
- Patrick J. Ward, MD Hematology & Oncology · Cincinnati, OH
- Stephen E. Depasquale, M.D. Gynecologic Oncology · Chattanooga, TN
- Axel Grothey, M.D. Hematology & Oncology · Germantown, TN
- Jason Porter, M.D. Hematology & Oncology · Germantown, TN
- Lauren A. Byers, M.D. Internal Medicine · Houston, TX
- Sarah Y. Wang, M.D. Hematology & Oncology · Tyler, TX
- Jun Zhang, MD Hematology & Oncology · Houston, TX
- Vaia Florou, MD Hematology & Oncology · Salt Lake City, UT
- Lindsay C. Overton, M.D. Hematology & Oncology · Wenatchee, WA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Ut MD Anderson Cancer Center $298,282
- Sarah Cannon Research Institute $172,354
- Baptist Health Lexington, KY $128,044
- Ronald Reagan UCLA Medical Center, CA $85,796
- Adventhealth Orlando, FL $84,464
- New York University $80,272
- Providence Medical Foundation $75,220
- Biomedical Research Alliance of New York LLC $72,907
- Titan Health PArtners, Llc $66,003
- Unehealth $57,172
- University of Maryland Baltimore $47,839
- The Methodist Hospital Research Institute $44,850
- UCSF Langley Porter Psychiatric Hospital and Clinics, CA $41,788
- Dana-Farber Cancer Institute $35,270
- West Cancer Center and Research Institute-East Campus $33,655
- Rush University Medical Center, IL $30,999
- Mary Hitchcock Memorial Hospital, NH $26,544
- Highlands Oncology Group $18,404
- Mercy Medical Center, OH $17,826
- Mercy Medical Research Institute $17,400
- Clinical Research Alliance $12,155
- Texas Oncology - Northeast Texas $2,815
- Regents of the University of Minnesota $2,749
- Los Angeles Cancer Network $2,580
- University of Utah Hospital and Clinics, UT $2,083
- Hackensack University Medical Center, NJ $1,667
- The West Clinic $1,648
- Clinical Research Providence $1,582
- Orchard Healthcare Research $1,533
- NYU Langone Health Perlmutter Cancer Center $1,463
- Icahn School of Medicine at Mount Sinai $1,331
- Erlanger Medical Center, TN $1,311
- Mercy Clinic Oncology and Hematology $1,269
- Confluence Health Clinical $1,213
- University of Miami $976
- Ohc Clinical Trials Program $876
- Astera Cancer Care East Brunswick $732
- University Miami Miller School of Medicine $190
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.