A Study of LY3841136 Compared With Placebo in Adult Participants With Obesity or Overweight
Completed · Phase 2 · NCT06230523
Conditions: Obesity, Overweight
At a glance
- Research payments reported, 2025
- $2.4M
- U.S. investigators named
- 47
- Sites paid
- 49
- Planned or actual enrollment
- 263
About the trial
- Sponsor
- Eli Lilly and Company
- Tested
- Eloralintide (drug), Placebo (drug)
- Dates
- Started 2024-02-05; completion 2025-08-14
- Results posted
- Yes
The main purpose of this study, performed under the master protocol W8M-MC-CWMM (NCT06143956), is to investigate weight management efficacy and safety with LY3841136 compared with placebo in adult participants with obesity or overweight. The study will last about 64 weeks and may include up to 17 visits.
From ClinicalTrials.gov, last updated 2026-06-24. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Eli Lilly and Company reported $2.4M in research payments for this study in 2025 (92 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Jitendra Sharma, M.B.B.S Neurology · Birmingham, AL
- Anita Kohli, MD Infectious Disease · Chandler, AZ
- Yessica R. Sachdeva, M.D. Internal Medicine · Mesa, AZ
- Mark P. Christiansen, MD Endocrinology & Diabetes · Walnut Creek, CA
- Linda M. Gaudiani, MD Endocrinology & Diabetes · Greenbrae, CA
- Stanley Hsia, M.D. Endocrinology & Diabetes · Los Angeles, CA
- Anirudh R. Nandan Student in an Organized Health Care Education/Training Program · San Francisco, CA
- Lawrence D. Sher, M.D. Pediatrics · Rolling Hills Estates, CA
- Cathy B. Barnes, MD Family Medicine · New Port Richey, FL
- Edgardo J. Riverarivera, MD Emergency Medicine · Leesburg, FL
- Senan Sultan, M.D. Endocrinology & Diabetes · Jacksonville, FL
- Alan Parsa, M.D. Endocrinology & Diabetes · Honolulu, HI
- Anuj Bhargava, MD Endocrinology & Diabetes · West Des Moines, IA
- Joseph R. Moore, M.D. Pediatrics · Ammon, ID
- Liana K. Billings, MD, MMSC Endocrinology & Diabetes · Skokie, IL
- Manish Jain, M.D. Rheumatology · Chicago, IL
- Susan R. Brian, MD Endocrinology & Diabetes · Topeka, KS
- Harold E. Bays, MD Endocrinology & Diabetes · Louisville, KY
- James P. Maynard, M.D. Neurology · Fort Thomas, KY
- Angela K. Fitch, MD Obesity Medicine · Boston, MA
- Jeffrey A. Norton, M.D. Pain Medicine · Lawrence, MA
- David J. Shih, MD Nephrology (Kidney) · North Dartmouth, MA
- Neil J. Fraser, MD Internal Medicine · Troy, MI
- David W. Strong, M.D., PH.D. Emergency Medicine · Detroit, MI
- Timothy R. Smith, M.D. Internal Medicine · Saint Peters, MO
- Rupal Trivedi, MD Family Medicine · Saint Louis, MO
- Awawu E. Igbinadolor, M.D. Adolescent Medicine · Monroe, NC
- Claire Presswood Internal Medicine · Morehead City, NC
- Cornell V. Calinescu, MD Emergency Medicine · Las Vegas, NV
- Barbara J. Connor, M.D. Obesity Medicine · Syracuse, NY
- Patrick M. Connors, M.D. Internal Medicine · Rochester, NY
- Robert C. Cupelo, M.D. Internal Medicine · East Syracuse, NY
- Laszlo L. Mechtler, MD Neurology · Amherst, NY
- Warren D. Spinner, D.O. Neurology · Port Jefferson Station, NY
- James D. Franklin III, M.D. Family Medicine · Greenville, SC
- Ronald K. Mayfield, M.D. Endocrinology & Diabetes · Spartanburg, SC
- Felix O. Berglund, MD Cardiology · Nashville, TN
- Saras Sharma, D.O. Gastroenterology · Nashville, TN
- Nitendra P. Agarwal, M.D., M.P.H. Hospitalist · San Antonio, TX
- Amer Al-karadsheh, M.D. Endocrinology & Diabetes · Houston, TX
- Michael J. Downing, MD Psychiatry · Dallas, TX
- Nomita J. Kim, MD Family Medicine · Austin, TX
- Jara K. Mcdonald, M.D. Family Medicine · Marble Falls, TX
- Julio Rosenstock, M.D. Endocrinology & Diabetes · Dallas, TX
- Brandon Lawrence, M.D. Orthopedic Surgery · Salt Lake City, UT
- Stephan H. Jannach, MD Family Medicine · Danville, VA
- Anton Grasch, MD Family Medicine · Wenatchee, WA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Monroe Biomedical Research $213,728
- Institute for Liver Health LLC $182,827
- Charter Research LLC $176,002
- Headlands Horizons LLC $163,274
- Sociedad Espanola De Medicina De La Adolescencia $142,118
- Great Lakes Clinical Trials $135,324
- Cti Holdings Inc DBA Community Research Management Associates Inc $118,205
- Rochester Clinical Research Inc $112,645
- Peninsula Headlands LLC $84,567
- Suncoast Clinical Research $78,313
- Las Vegas Medical Research LLC $75,813
- Studymetrix Research LLC $74,795
- Endocrine Ips PLLC $66,868
- Arcturus Healthcare PLC, Troy Internal $54,959
- Louisville Metabolic $48,457
- Tekton Research Inc $48,052
- Pacific Diabetes and Endocrine Center $46,899
- Velocity Clinical Research Inc $43,937
- Medication Management LLC $43,711
- Cotton Oneil Msd of Stormont Vail Healthcare $43,245
- Dent Neurosciences Research Center Inc $41,446
- Central Washington Health Services $41,103
- Lucida Clinical Trials $39,557
- Tribe Clinical Research LLC $39,141
- Danville Orthopedic Clinic Inc $31,129
- Lucas Research Inc $29,842
- Future Search Trials of Dallas LP $29,310
- Norcal Medical Research Inc $26,550
- Ascension Medical Group $22,957
- Medical Research PArtners $20,299
- Erg Holding Co LLC DBA St Louis Clinical Trials LLC $20,299
- Ima Evaluations LLC DBA Ima Clinical Research $12,178
- Iowa Diabetes and Endocrinology Rsrch Cntr $11,721
- Northshore University Healthsystem - Evanston Hospital, IL $10,958
- Seen Medical of Ma PC DBA Knownwell $8,091
- University at Buffalo $5,995
- Palos Verdes Medical Group $3,084
- Dallas Diabetes and Endo Research Center PA $2,080
- Lightship Inc $1,990
- Knownwell $1,634
- Futuresearch Trials of Neurology LP $1,327
- Northeast Research Institute $1,320
- Medex Healthcare Research Inc $1,182
- Endeavor Clinical Trials PA $1,033
- Yshay Shlesinger MD $1,026
- Wenatchee Valley Hospital $749
- Andrew J Lewin Med DBA National Rsrch Institute $525
- North Suffolk Neurology $505
- Cleveland Clinic, OH $232
- $5
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.