Phase 1a/1b First-in-Human Study of BG-C9074 Alone and in Combination With Other Anticancer Therapies in Patients With Advanced Solid Tumors
Recruiting · Phase 1 · NCT06233942
Conditions: Advanced Solid Tumor
At a glance
- Research payments reported, 2025
- $957,579
- U.S. investigators named
- 5
- Sites paid
- 5
- Planned or actual enrollment
- 308
About the trial
- Sponsor
- BeOne Medicines
- Tested
- BG-C9074 (drug), Tislelizumab (drug), Bevacizumab (drug)
- Dates
- Started 2024-04-12; completion 2028-05-15
- Results posted
- Not yet
This is a first-in-human, dose finding and dose expansion study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of BG-C9074 alone and in combination with other anticancer therapies in patients with advanced solid tumors.
From ClinicalTrials.gov, last updated 2026-09-16. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Beone Medicines Ltd. reported $957,579 in research payments for this study in 2025 (252 payments).
Products named: Tevimbra
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Diana L. Hanna, M.D. Medical Oncology · Newport Beach, CA
- Jennifer Diamond, MD Hematology & Oncology · Aurora, CO
- Cesar A. Perez Batista, M.D. Medical Oncology · Orlando, FL
- Stephanie L. Gaillard, MD, PHD Medical Oncology · Baltimore, MD
- Kai C. Johnson, MD Medical Oncology · Columbus, OH
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Florida Cancer Specialist (scri) - Fort Myers $369,055
- University of Colorado Cancer Center $229,951
- University of Southern California, Norris Comprehensive Cancer Center $153,677
- The Ohio State University Dba: Comprehensive Canc $124,158
- The Johns Hopkins University $80,738
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.