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Phase II Study of Pirtobrutinib, Rituximab (PR) in Previously Untreated Low and Intermediate Risk MCL (Mantle Cell Lymphoma) Patients

Recruiting · Phase 2 · NCT06263491

Conditions: Mantle Cell Lymphoma

At a glance

Research payments reported, 2025
$654,039
U.S. investigators named
1
Sites paid
1
Planned or actual enrollment
50

About the trial

Sponsor
M.D. Anderson Cancer Center
Tested
Rituximab (drug), Pirtobrutinib (drug)
Dates
Started 2024-05-29; completion 2027-03-01
Results posted
Not yet

To learn if the chemotherapy-free combination of pirtobrutinib (also called LOXO-305) and rituximab can help provide long term remission in low and intermediate risk MCL.

From ClinicalTrials.gov, last updated 2026-04-23. Full record, eligibility and contacts (opens in a new tab)

Industry funding

Lilly USA, LLC reported $654,039 in research payments for this study in 2025 (1 payments).

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • Ut MD Anderson Cancer Center $654,039

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.