A Dose-finding Trial With Lu-AG09222 in Adults With Migraine Who Have Not Been Helped by Prior Preventive Treatments
Completed · Phase 2 · NCT06323928
Conditions: Migraine
At a glance
- Research payments reported, 2025
- $1.5M
- U.S. investigators named
- 28
- Sites paid
- 19
- Planned or actual enrollment
- 874
About the trial
- Sponsor
- H. Lundbeck A/S
- Tested
- Lu AG09222 (drug), Placebo (drug)
- Dates
- Started 2024-04-01; completion 2026-03-16
- Results posted
- Not yet
The purpose of this trial is to determine which doses of Lu AG09222 are recommended to help prevent migraines. People who join this trial have already tried 1 to 4 other available medications to prevent their migraines, but these medications have not helped them.
From ClinicalTrials.gov, last updated 2026-06-12. Full record, eligibility and contacts (opens in a new tab)
Industry funding
H. Lundbeck A S reported $1.5M in research payments for this study in 2025 (470 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Diane R. Counce, MD Neurology · Birmingham, AL
- Anthony M. Ciabarra, M.D., PH.D. Neurology · Fullerton, CA
- Neeraj Gupta, M.D. Internal Medicine · Long Beach, CA
- Nirav S. Patel, M.D. Neurology · Los Alamitos, CA
- Jack D. Schim, M.D Neurology · Carlsbad, CA
- Peter J. Mcallister, M.D. Neurology · Fairfield, CT
- Jessica Ailani, MD Neurology · Washington, DC
- Sheila M. Baez-torres, M.D. Neurology · Winter Park, FL
- Matthew J. Baker, MD Neurology · Naples, FL
- Lisa M. Cohen, D. O. Family Medicine · Palm Harbor, FL
- John M. Joyce, M. D. Psychiatry · Jacksonville, FL
- Kelley A. Wilson, M.D. Psychiatry · Tampa, FL
- Paul K. Winner, D.O. Child Neurology · West Palm Beach, FL
- David B. Moore, M.D. Neurology · Ames, IA
- Larry D. Reed, M.D. Radiology · Jerseyville, IL
- Nicholas Weber, DO Family Medicine · Eureka, IL
- Siddharth Kaul, MD Neurology · Bridgeton, MO
- David A. Browder, MD Internal Medicine · Rocky Mount, NC
- Marshall C. Freeman, MD Neurology · Greensboro, NC
- Mitchell G. Isaac, MD Neurology · Winston Salem, NC
- John Rubino, MD Internal Medicine · Raleigh, NC
- Sylvia P. Shoffner, MD Internal Medicine · Cary, NC
- Warren D. Spinner, D.O. Neurology · Port Jefferson Station, NY
- Deborah A. Reed, M.D. Neurology · Medina, OH
- Richard E. Mills, MD Internal Medicine · Mt Pleasant, SC
- Bernard Grunstra, MD Internal Medicine · Bristol, TN
- Adeyemi T. Gbohunmi, M.D., PH.D. General Practice · Fort Worth, TX
- Shahin Shirzadi, M.D. Neurology · Houston, TX
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Accellacare US Inc $425,034
- M3 Wake Research Inc $189,992
- Clinical Research Professionals Inc $173,403
- Ki Clinical Research $119,322
- Profound Research LLC $106,160
- Academic Alliance in Dermatology $83,132
- Nevada Advanced PAin Specialists $69,601
- Mercury Clinical Research Inc $65,967
- Cedar Health Research Inc $52,594
- Medstar Georgetown University Hospital $39,129
- Palm Beach Neurology $36,227
- Achieve Clinical Research LLC $27,709
- Neurology Center of North Orange County A Medical Corp $25,865
- Clinical Neuroscience Solutions Inc $21,050
- Aqualane Clinical Research LLC $19,259
- Robbins Headache Clinic $17,700
- Medical College of Wisconsin $15,560
- Multicare Neuroscience $10,500
- Avantex $7,567
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.