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An Observational Study to Investigate the Use of Aflibercept 8 mg to Treat Adult Patients With Neovascular Age-Related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) in a Real-World Setting

Withdrawn · NCT06398080

Conditions: Neovascular Age-related Macular Degeneration (nAMD), Wet Age-related Macular Degeneration (AMD), Diabetic Macular Edema (DME), Visual Impairment

At a glance

Research payments reported, 2025
$10,249
U.S. investigators named
5
Sites paid
5

About the trial

Sponsor
Regeneron Pharmaceuticals
Tested
aflibercept 8 mg (drug)
Dates
Started 2024-12-12; completion 2029-01-03
Results posted
Not yet

The purpose of this research study is to observe the patient's clinical care and how EYLEA® HD is used as a treatment in real-world settings. Patients are asked to join the study because they have either neovascular age-related macular degeneration (nAMD/wet age-related macular degeneration \[AMD\]) or diabetic macular edema (DME). Patients cannot have used EYLEA® HD in the past and the doctor must be planning to treat nAMD or DME with a new prescription of EYLEA® HD (aflibercept 8 mg).

From ClinicalTrials.gov, last updated 2024-11-25. Full record, eligibility and contacts (opens in a new tab)

Industry funding

Regeneron Pharmaceuticals, Inc. reported $10,249 in research payments for this study in 2025 (5 payments).

Products named: Eylea Hd

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • Northern California Retina Vitreous Association $5,000
  • Retina Macula Institute of Arizona $2,000
  • Foundation for Vision Research $1,779
  • Red River Research PArtners LLC $1,000
  • Retina Consultants of Alabama $470

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.