An Observational Study to Investigate the Use of Aflibercept 8 mg to Treat Adult Patients With Neovascular Age-Related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) in a Real-World Setting
Withdrawn · NCT06398080
Conditions: Neovascular Age-related Macular Degeneration (nAMD), Wet Age-related Macular Degeneration (AMD), Diabetic Macular Edema (DME), Visual Impairment
At a glance
- Research payments reported, 2025
- $10,249
- U.S. investigators named
- 5
- Sites paid
- 5
About the trial
- Sponsor
- Regeneron Pharmaceuticals
- Tested
- aflibercept 8 mg (drug)
- Dates
- Started 2024-12-12; completion 2029-01-03
- Results posted
- Not yet
The purpose of this research study is to observe the patient's clinical care and how EYLEA® HD is used as a treatment in real-world settings. Patients are asked to join the study because they have either neovascular age-related macular degeneration (nAMD/wet age-related macular degeneration \[AMD\]) or diabetic macular edema (DME). Patients cannot have used EYLEA® HD in the past and the doctor must be planning to treat nAMD or DME with a new prescription of EYLEA® HD (aflibercept 8 mg).
From ClinicalTrials.gov, last updated 2024-11-25. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Regeneron Pharmaceuticals, Inc. reported $10,249 in research payments for this study in 2025 (5 payments).
Products named: Eylea Hd
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Jason Crosson, MD Ophthalmology · Apo, AE
- Mark R. Barakat, M.D. Ophthalmology · Scottsdale, AZ
- James D. Palmer, MD Ophthalmology · Mountain View, CA
- Scott J. Westhouse, D.O. Ophthalmology · Grand Rapids, MI
- Hemang K. Pandya, M.D. Retina Specialist · Plano, TX
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Northern California Retina Vitreous Association $5,000
- Retina Macula Institute of Arizona $2,000
- Foundation for Vision Research $1,779
- Red River Research PArtners LLC $1,000
- Retina Consultants of Alabama $470
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.