A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)
Recruiting · Phase 3 · NCT06439277
Conditions: Obesity, Weight Gain
At a glance
- Research payments reported, 2025
- $1.6M
- U.S. investigators named
- 23
- Sites paid
- 28
- Planned or actual enrollment
- 300
About the trial
- Sponsor
- Eli Lilly and Company
- Tested
- Tirzepatide (drug), Placebo (drug)
- Dates
- Started 2024-06-03; completion 2030-12
- Results posted
- Not yet
The goal of the study is to assess how tirzepatide impacts bodyweight and cardiovascular risk factors when used in conjunction with healthy nutrition and physical activity in adolescents with obesity and multiple weight related comorbidities. The study will last approximately 76 weeks and may include up to 23 visits. Participants who have completed the primary 72-week GPIX study and have been off treatment for no more than 12 weeks (including the 4-week safety follow-up period), will have the opportunity to receive an additional 156 weeks of treatment with tirzepatide as well as continuing the lifestyle intervention.
From ClinicalTrials.gov, last updated 2026-09-24. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Eli Lilly and Company reported $1.6M in research payments for this study in 2025 (46 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- William H. Johnston JR., MD Pediatrics · Birmingham, AL
- Gnanagurdasan Prakasam, MD Pediatric Endocrinology · Sacramento, CA
- Alaina P. Vidmar, M.D. Pediatric Endocrinology · Los Angeles, CA
- Chijioke Ikomi, M.D Pediatrics · Wilmington, DE
- Kimball A. Johnson, MD Internal Medicine · Atlanta, GA
- Joseph R. Moore, M.D. Pediatrics · Ammon, ID
- Jami L. Josefson, M.D. Pediatric Endocrinology · Chicago, IL
- Tamara S. Hannon, M.D. Pediatric Endocrinology · Indianapolis, IN
- Margaret A. Stefater-richards, MD, PHD Pediatric Endocrinology · Boston, MA
- David W. Hansen, MD Pediatric Endocrinology · Syracuse, NY
- Lucy D. Mastrandrea, MD, PH Pediatric Endocrinology · Buffalo, NY
- Marcy J. Goisse, MD Family Medicine · Smithfield, PA
- Francisco Nieves-rivera, MD Pediatric Endocrinology · San Juan, PR
- Carole I. Mercer, M.D. Adolescent Medicine · Simpsonville, SC
- Hareshkumar D. Boghara, M.D. Family Medicine · Desoto, TX
- Alejandro Gonzalez Campos, M.D Endocrinology & Diabetes · Edinburg, TX
- Alex Guevara JR., D.O. Family Medicine · Fort Worth, TX
- Syed H. Haider, M.D. Pediatrics · Katy, TX
- Rocio A. Harbison, MD Endocrinology & Diabetes · Houston, TX
- Eduardo D. Luna, M.D. Endocrinology & Diabetes · Edinburg, TX
- Ana M. Paez, MD Pediatric Endocrinology · Corpus Christi, TX
- Michelle D. Welch, MD Endocrinology & Diabetes · Shavano Park, TX
- Peter E. Silas, M.D. Pediatrics · Syracuse, UT
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Texas Valley Clinical Research LLC $377,579
- Driscoll Childrens Hospital, TX $211,618
- Ann & Robert H Lurie Childrens Hospital of Chicago, IL $174,714
- Consano Clinical Research LLC $165,500
- Nemours Children's Hospital, Delaware, DE $121,421
- Research Foundation of State Univ of Ny $111,499
- Indiana University $97,119
- Sutter Medical Center, Sacramento, CA $95,164
- Children's Hosp of Los Angeles, CA $63,307
- Alliance for Multispecialty Research Lls $60,377
- Epic Medical Research $57,777
- Valley Institute of Research LLC $33,725
- Cenexel Iresearch LLC $19,921
- Medical Research PArtners $19,281
- Faculty Association of the State University of New York at Stony Brook $3,504
- Frontier Clinical Research LLC $3,251
- Center of Excellence in Diabetes $2,655
- Central Research Associates, Inc $2,651
- $1,551
- Biopharma Informatic Inc $1,315
- Cotton Oneil Msd of Stormont Vail Healthcare $1,288
- Mountain View Clinical Research Inc $1,220
- Boston Children's Hospital, MA $1,220
- Medical Education & Research Foundation Inc $678
- Flourish Research Acquisition LLC $600
- Upstate Medical University $522
- Juno Research LLC $507
- Tribe Clinical Research LLC $95
- Suny Upstate Medical University $4
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.