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NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trial

Recruiting · Phase 2 · NCT06450041

Conditions: Neuroblastoma

At a glance

Research payments reported, 2025
$53,114
U.S. investigators named
1
Sites paid
1
Planned or actual enrollment
62

About the trial

Sponsor
New Approaches to Neuroblastoma Therapy Consortium (with Nationwide Children's Hospital, United Therapeutics, Children's Neuroblastoma Cancer Fund)
Tested
Universal Donor (UD) TGFβi NK Cells (drug), Temozolomide (drug), Irinotecan (drug), Dinutuximab (drug), GM-CSF (drug)
Dates
Started 2024-12-16; completion 2038-12
Results posted
Not yet

This is a phase II study looking at patient response to treatment with the combination dinutuximab, temozolomide, irinotecan, and GM-CSF.

From ClinicalTrials.gov, last updated 2026-07-20. Full record, eligibility and contacts (opens in a new tab)

Industry funding

United Therapeutics Corporation reported $53,114 in research payments for this study in 2025 (3 payments).

Products named: Unituxin

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.