A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa
Active, not recruiting · Phase 3 · NCT06468228
Conditions: Hidradenitis Suppurativa
At a glance
- Research payments reported, 2025
- $7.8M
- U.S. investigators named
- 66
- Sites paid
- 66
- Planned or actual enrollment
- 1,400
About the trial
- Sponsor
- AbbVie
- Tested
- Lutikizumab (drug), Placebo (drug)
- Dates
- Started 2024-06-27; completion 2026-12
- Results posted
- Not yet
Hidradenitis suppurativa (HS) is a chronic and often painful inflammatory skin disease which includes the forming of lumps, abscesses and scars in areas of the skin such as under the breasts, under armpits, inner thighs, groin and buttocks. This study will compare lutikizumab versus placebo for the treatment of adult and adolescent participants with the signs and symptoms of moderate to severe HS . Lutikizumab is an investigational drug being developed for the treatment of HS. During Period 1 of the study, participants will placed in 1 of 2 groups called treatment arms. There is a 1 in 2 chance that participants will be assigned to placebo. Around 1280 adult and adolescent participants wi…
From ClinicalTrials.gov, last updated 2026-09-02. Full record, eligibility and contacts (opens in a new tab)
Industry funding
AbbVie Inc. reported $7.8M in research payments for this study in 2025 (774 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Vlada Groysman, MD Dermatology · Hoover, AL
- Scott M. Dinehart, M.D. Mohs Surgery · Little Rock, AR
- Dowling B. Stough IV, MD Dermatology · Hot Springs, AR
- Lindsay S. Ackerman, MD Dermatology · Phoenix, AZ
- Maria A. Aleshin, MD Dermatology · Stanford, CA
- Daniel Butler, M.D. Internal Medicine · San Francisco, CA
- Navid Ezra, M.D. Dermatology · Thousand Oaks, CA
- Tooraj J. Raoof, MD Internal Medicine · Encino, CA
- Raja Sivamani, M.D., M.S., A.H.E. Dermatology · Sacramento, CA
- Howard L. Sofen, M.D. Dermatology · Los Angeles, CA
- Francis A. Caban, M.D. Dermatology · Brandon, FL
- Ashley Cauthen, M.D. Dermatology · Ocala, FL
- Christopher D. Ewanowski, M.D. Dermatology · Lutz, FL
- Brad P. Glick, MD Dermatology · Margate, FL
- Francisco A. Kerdel, MD Dermatology · Miami, FL
- Ann Lin, DO Dermatology · Tampa, FL
- Stephen J. Lockwood, MD Dermatology · Brandon, FL
- Luis T. Menendez, M.D. Dermatology · Tampa, FL
- Michael A. Scannon, M.D. Dermatology · Tampa, FL
- Tory Sullivan, M.D. Dermatology · North Miami Beach, FL
- Andleeb A. Usmani, D.O. Dermatology · Miami, FL
- Eduardo T. Weiss, MD Dermatology · Hollywood, FL
- Nathan J. Cleaver, DO Dermatology · Cumming, GA
- Joshua E. Lane, M.D. Mohs Surgery · Columbus, GA
- Michael Bukhalo, MD Dermatology · Rolling Meadows, IL
- Kelsey Flood, MD Dermatology · Chicago, IL
- George M. Lewitt, M.D. Dermatology · Northbrook, IL
- Scott A. Fretzin, M.D. Dermatology · Indianapolis, IN
- Anne M. Blake, MD Dermatology · Leawood, KS
- Mark H. Fleischman, MD Mohs Surgery · Leawood, KS
- James Allred, MD Dermatology · Franklin, KY
- Cindy E. Owen, M.D. Dermatology · Louisville, KY
- Erin E. Boh, MD PHD Dermatology · New Orleans, LA
- Alexandra B. Kimball, MD MPH Dermatology · Boston, MA
- Sarah K. Whitley, MD Dermatology · Worcester, MA
- Iltefat H. Hamzavi, MD Dermatology · Canton, MI
- Wendy L. Mcfalda, D.O. Dermatology · Clarkston, MI
- Neetu Talreja, MD Hospitalist · Detroit, MI
- Melody Stone, MD Dermatology · Saint Joseph, MO
- Rita O. Pichardo, MD Dermatopathology · Winston Salem, NC
- Natalie M. Fragoso, M.D. Dermatology · Lebanon, NH
- Abel D. Jarell, MD Dermatology · Portsmouth, NH
- Victoria G. Farley, M.D. Dermatology · Las Vegas, NV
- Ahuva Cices, MD Dermatology · New York, NY
- Jorge A. Garcia-zuazaga, M.D. Mohs Surgery · Concord Township, OH
- Jessica A. Kaffenberger, M.D. Dermatology · Columbus, OH
- Rocco T. Serrao, MD Dermatology · Dayton, OH
- Matthew J. Zirwas, MD Dermatology · Bexley, OH
- Jason M. Schoenfeld, M.D. Mohs Surgery · Philadelphia, PA
- Joe K. Tung, MD, MBA Dermatology · Pittsburgh, PA
- Alma M. Cruz Santana, MD Dermatology · Carolina, PR
- Maria I. Martinez Colon, M.D. Dermatology · San Juan, PR
- Amylynne J. Frankel, M.D. Dermatology · Spartanburg, SC
- Todd E. Schlesinger, M.D. Dermatology · Charleston, SC
- Lara Wine Lee, M.D. Dermatology · Charleston, SC
- William Abramovits, M.D. Dermatology · Dallas, TX
- John C. Browning, MD Dermatology · San Antonio, TX
- Lauren S. Campbell, M.D. Dermatology · Cypress, TX
- Jennifer D. Holman, MD Dermatology · Tyler, TX
- Angela Y. Moore, MD, PA Dermatopathology · Arlington, TX
- So Yeon Paek, M.D. Dermatology · Dallas, TX
- Craig F. Teller, M.D. Dermatology · Bellaire, TX
- Stephen K. Tyring, MD PHD Dermatology · Webster, TX
- Jamie L. Rhoads, M.D. Dermatology · Murray, UT
- David Pariser, M.D. Dermatology · Norfolk, VA
- Katherine B. Reed, M.D. Dermatology · Spokane, WA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Integrative Skin Science $495,801
- Skin Care Research Inc $386,123
- Texas Dermatology Research Center $314,740
- Dermatology and Skin Cancer $305,163
- Cr Services Acquisition US LLC $285,120
- Icahn School of Med at Mt Sinai $268,405
- Apex Clinical Research Center LLC $257,660
- Ds Research of Kentucky LLC $229,587
- Clinical Research Puerto Rico Inc $223,269
- Cahaba Derm & Skin Health Ctr LLC $220,909
- University of Pittsburgh Physicians $219,467
- T Joseph Raoof MD Inc $211,250
- Cleaver Medical Group Dermatology $186,385
- Dermatologists of Southwest Ohio Inc $183,813
- Reveal Research Institute PLLC $174,278
- Advanced Dermatology of Sc PC $169,280
- Oliver Street 501 (a) Inc $165,393
- Caban Health LLC $159,488
- Dermatology Trial Associates $158,422
- Equity Medical LLC $148,038
- Center for Clinical Studies LTD LLP $141,789
- Studies in Dermatology LLC $138,552
- Southwest Skin Specialists LLC $135,615
- Dermatology Specialists of Spokane $132,388
- Clinical Research Philadelphia LLC $127,649
- Dermatologists of Southwest Ohio $111,127
- University of Utah Hospital and Clinics, UT $108,793
- University of South Florida $106,395
- Treasure Valley Medical Research $97,398
- Medical University South Carolina $96,729
- Renstar LLC $96,532
- Texas Dermatology and Laser $93,338
- Michigan Center for Research $90,494
- Bellaire Dermatology Associates $88,584
- Alma M Cruz-Santana $87,169
- Fife Dermatology PC $84,819
- Ziaderm Research LLC $83,558
- Michael Bukhalo MD Sc $82,566
- Wake Forest University $80,330
- Gsi Clinical Research LLC $79,668
- Apex Clinical Trials LLC $78,848
- Arlington Research Center Inc $73,884
- Dawes Fretzin Clinical Research $69,329
- Beth Israel Deaconess Medical Center, MA $69,261
- Virginia Clinical Research Inc $65,025
- Arkansas Research Trials LLC $53,535
- Crcc $52,082
- Dermatology Research Associates Inc $50,340
- The University of Arizona $48,104
- The Ohio State University $47,963
- Hamzavi Dermatology $45,480
- Moore Clinical Research Inc $36,671
- Truderm Research LLC $34,508
- Clinical Trials Research Institute $31,306
- The Administrators of the Tulane $22,646
- $20,915
- Stracskin PLLC $19,800
- Medisearch Clinical Trials $19,437
- University of Massachusetts $18,442
- Dartmouth Hitchcock Health $15,752
- Palm Harbor Dermatology $12,999
- Arano PLLC $12,600
- The Board of Trustees of the Leland $9,674
- Florida Academic Dermatology Center $9,500
- Northwestern University $7,227
- Alliance Clinical Research of Tampa $3,778
- Allcutis Research LLC $931
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.