A Clinical Study to Investigate the Safety and Immunogenicity in Relation to Product Attributes of mRNA-1083 (Severe Acute Respiratory Syndrome Coronavirus 2 [SARS-CoV-2] and Influenza Vaccine)
Completed · Phase 2 · NCT06508320
Conditions: Influenza, SARS-CoV-2
At a glance
- Research payments reported, 2025
- $3.1M
- U.S. investigators named
- 12
- Sites paid
- 13
- Planned or actual enrollment
- 931
About the trial
- Sponsor
- ModernaTX, Inc.
- Tested
- mRNA-1083 (biological)
- Dates
- Started 2024-07-15; completion 2025-09-25
- Results posted
- Yes
The purpose of this study is to evaluate the safety, reactogenicity, and immunogenicity in relation to the product attributes of mRNA-1083 vaccine when administered as a single intramuscular (IM) injection in adults ≥50 to \<65 years of age.
From ClinicalTrials.gov, last updated 2026-10-08. Full record, eligibility and contacts (opens in a new tab)
Industry funding
ModernaTX, Inc. reported $3.1M in research payments for this study in 2025 (98 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Jose F. Cardona, M.D. General Practice · Miami, FL
- Mark E. Kutner, MD Internal Medicine · Miami, FL
- Craig S. Shapiro, D.O. ENT (Otolaryngology) · Hollywood, FL
- Kimball A. Johnson, MD Internal Medicine · Atlanta, GA
- Mary Brown, MD Internal Medicine · Rockford, IL
- Carlos A. Fierro, MD General Practice · Kansas City, KS
- Michael A. Hassman, DO Family Medicine · Berlin, NJ
- Megan Algeo, M.D. Emergency Medicine · Philadelphia, PA
- Douglas S. Denham, D.O. Family Medicine · San Antonio, TX
- Lisa R. Holloway, D.O. Family Medicine · Houston, TX
- Muhammad Irfan, M.D. Internal Medicine · Tomball, TX
- Vicki E. Miller, M.D. Family Medicine · Pasadena, TX
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Research Centers of America LLC $1.1M
- Indago Research and Health Center Inc $442,048
- Suncoast Research Group LLC $428,712
- Cenexel Iresearch LLC $278,842
- Research Centers of America $194,855
- Dynamed Clinical Research LP $186,996
- Johnson County Clintrials $171,393
- Dynamed Chicago LLC $117,968
- Dynamed Philadelphia LLC $110,897
- Clinical Trials of Texas Inc. $57,763
- Hassman Research Institute LLC $57,138
- Indago Research and Health $15,090
- Clinical Trials of Texas Inc $2,500
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.