A Study of Mevidalen (LY3154207) in Participants With Alzheimer's Disease
Completed · Phase 2 · NCT06538116
Conditions: Alzheimer Disease
At a glance
- Research payments reported, 2025
- $11.5M
- U.S. investigators named
- 46
- Sites paid
- 48
- Planned or actual enrollment
- 304
About the trial
- Sponsor
- Eli Lilly and Company
- Tested
- Mevidalen (drug), Placebo (drug)
- Dates
- Started 2024-08-26; completion 2026-05-11
- Results posted
- Not yet
The main purpose of this study is to look at how safe the study drug (mevidalen) is and whether it works to alleviate symptoms when given to people with mild to moderate Alzheimer Disease (AD) dementia. This is done by looking at participants: thinking and memory (cognition), everyday activities and sleep, AD symptoms, physical activity, irritability or anxiety. The study is expected to last approximately 26 weeks and may include up to 14 visits.
From ClinicalTrials.gov, last updated 2026-06-18. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Eli Lilly and Company reported $11.5M in research payments for this study in 2025 (98 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Perminder Bhatia, MD Neurology · Fresno, CA
- Ezekiel Fink, MD Pain Medicine · Beverly Hills, CA
- Benjamin M. Frishberg, M.D. Neurology · Carlsbad, CA
- Maria I. Seliverstov, M.D. Psychiatry · Sherman Oaks, CA
- Malisa Agard, M.D. Internal Medicine · Orlando, FL
- Vikram M. Atit, MD Neurology · Holiday, FL
- Diana Balsalobre, M.D. Neurology · Apopka, FL
- Mauricio Concha, MD Neurology · Sarasota, FL
- Victor Faradji, MD Neurology · Miami, FL
- John Huffaker, ARNP Nurse Practitioners · Venice, FL
- Nandita J. Jones, MD Psychiatry · Jacksonville, FL
- David A. Kirk Family Medicine · Merritt Island, FL
- Gregory A. Kirk, M.D. Family Medicine · Merritt Island, FL
- Ayesha S. Lall, MD Child & Adolescent Psychiatry · Gainesville, FL
- Anette Nieves, MD Neurology · Ocala, FL
- Linda Pao, MD Neurology · Jupiter, FL
- Paayal K. Patel, M.D Neurology · West Palm Beach, FL
- Julie B. Schwartzbard, MD Neurology · Aventura, FL
- Alexander White, MD Family Medicine · Daytona Beach, FL
- Paul K. Winner, D.O. Child Neurology · West Palm Beach, FL
- Rasha R. Youssef, M.D. Family Medicine · Boynton Beach, FL
- Yael R. Elfassy, M.D. Pediatrics · Savannah, GA
- Kimball A. Johnson, MD Internal Medicine · Atlanta, GA
- Marshall L. Nash, M.D. Neurology · Decatur, GA
- Kore K. Liow, MD Neurology · Honolulu, HI
- Concetta M. Forchetti, M.D. Neurology · Elk Grove Village, IL
- Kristi K. George, MD Neurology · Indianapolis, IN
- Deborah M. Green-laroche, MD Neurology · Boston, MA
- Stephen M. Miller JR., M.D. General Surgery · Boston, MA
- Aaron L. Ellenbogen, D.O. Neurology · Farmington Hills, MI
- Mohammad R. Bolouri, MD Neurology · Matthews, NC
- Singaravelu Jagadeesan, MD Neurology · Gastonia, NC
- Sanjiv K. Sharma, M.D. Internal Medicine · Toms River, NJ
- Arun Singh, M.D. Emergency Medicine · Toms River, NJ
- Hooman Kamel, MD Neurology · New York, NY
- Stephen E. Litman, MD Internal Medicine · Dresher, PA
- Stephen A. Volk, MD Hematology & Oncology · Fountain Hill, PA
- Lora J. Mcgill, M.D. Neurology · Memphis, TN
- Mark D. Carlson, MD Internal Medicine · Cedar Park, TX
- Douglas S. Denham, D.O. Family Medicine · San Antonio, TX
- James A. Falcon, M.D. Family Medicine · Rio Grande City, TX
- Aimee C. Garza, MD Neurology · Frisco, TX
- Diana R. Kerwin, MD Geriatric Medicine · Dallas, TX
- Jamshid Lotfi, MD Neurology · Houston, TX
- Jaron L. Winston, M.D. Psychiatry · Austin, TX
- Michael H. Rosenbloom, MD Neurology · Seattle, WA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Flourish Research Acquisition LLC $1.8M
- Charter Research LLC $870,525
- Clinical Trial Network LLC $717,655
- Progressive Medical Concepts LLC $623,070
- Conquest Research LLC $613,475
- Renstar Inc $579,816
- Visionary Investigators Network $480,046
- Hawaii PAcific Neuroscience LLC $466,415
- Sandhill Research LLC $370,253
- Premier Research Institute $366,151
- Cedar Health Research $346,891
- Jem Headlands LLC $344,635
- Profound Research LLC $332,583
- Cenexel Iresearch LLC $308,997
- Activmed Practices and Research LLC $297,070
- Alexian Brothers Health System $284,262
- University of Washington Medical Ctr, WA $273,432
- Neuro PAin Medical Center Inc $259,077
- Erg Holding Co LLC DBA St Louis Clinical Trials LLC $203,511
- Advanced Memory Research Institute of Nj PC $202,292
- Quest Research Institute LLC $197,291
- Intercoastal Medical Group $186,706
- Thomas M Shiovitz MD Inc $181,684
- Atlas Intermediate $179,118
- Kerwin Memory Center LLC $168,969
- Be Well Clinical Studies LLC $168,807
- El Faro Health and Therapeutics PLLC $154,048
- Eximia Research - Nc, LLC $151,494
- Josephson Wallack Munshower Neurology $138,030
- Clinical Neuroscience Solutions DBA Cns Hlthcare $91,979
- Senior Adult Specialty Research $61,900
- Vertex Clinical Research LLC $16,856
- Southern California Dermatology Inc $8,362
- Alzheimers Memory Center $7,694
- Brain Matters Research Inc $3,613
- Suncoast Clinical Research $3,286
- $2,985
- Glendale Neurological Associates $2,285
- Kerwin Research Center LLC $2,268
- Excel Medical Clinical Trials, LLC $1,967
- Yale University $1,535
- Hkamel Consulting LLC $1,400
- Catalina Research Institute LLC $668
- Clinical Trials of Texas Inc $360
- Merritt Island Medical Research LLC $274
- Jem Research LLC $195
- Advocare Berlin Medical Associates $195
- Neuropsychiatric Associates of Southwest Fl PA $195
- Activmed Practices and Research Inc $195
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.