Evaluate Efficacy and Safety of POS to Improve Distance-corrected Near Visual in Participants With Presbyopia
Completed · Phase 3 · NCT06542497
Conditions: Presbyopia
At a glance
- Research payments reported, 2025
- $649,297
- U.S. investigators named
- 28
- Sites paid
- 28
- Planned or actual enrollment
- 569
About the trial
- Sponsor
- Opus Genetics, Inc
- Tested
- 0.75% phentolamine ophthalmic solution (drug), Placebo (drug)
- Dates
- Started 2024-08-15; completion 2026-01-22
- Results posted
- Yes
Safety and efficacy of POS in participants with presbyopia
From ClinicalTrials.gov, last updated 2026-10-26. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Oyster Point Pharma, Inc. reported $649,297 in research payments for this study in 2025 (91 payments).
Products named: Ryzumvi
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Marc Bloomenstein, OD Optometrists · Scottsdale, AZ
- Matthew D. Hammond, MD Ophthalmology · Mesa, AZ
- Benjamin Heller Ophthalmology · Phoenix, AZ
- Sherif M. El-harazi, MD MPH Ophthalmology · Glendale, CA
- Damien F. Goldberg, M.D. Ophthalmology · Torrance, CA
- David J. Schanzlin, M.D. Ophthalmology · San Diego, CA
- David L. Wirta, MD Ophthalmology · Newport Beach, CA
- Keith C. Charles, MD Ophthalmology · Mount Dora, FL
- Frank W. Mcdonald, M.D. Ophthalmology · Jacksonville, FL
- Christopher Pearson, O.D. Optometrists · Longwood, FL
- Bruce A. Segal, MD Ophthalmology · Delray Beach, FL
- Philip L. Shettle, D.O. Ophthalmology · Largo, FL
- Erin C. Esfahani, NP Nurse Practitioners · Marietta, GA
- Kathleen A. Kelley, O.D. Optometrists · Indianapolis, IN
- Shane R. Kannarr, OD Optometrists · Pittsburg, KS
- Bradley R. Kwapiszeski, M.D. Ophthalmology · Shawnee Mission, KS
- Jason E. Stahl, MD Ophthalmology · Overland Park, KS
- Mahdi Basha, D.O. Ophthalmology · Fraser, MI
- Anthony J. Verachtert, O.D. Optometrists · Kansas City, MO
- Carol A. Aune, OD Optometrists · Raleigh, NC
- Nicole M. Collins, O.D. Optometrists · Fargo, ND
- Paul J. Hartman, MD Ophthalmology · Rochester, NY
- Stephen M. Montaquila, O.D. Optometrists · Warwick, RI
- David G. Evans, OD Optometrists · Memphis, TN
- Bradley N. Hines, O.D. Optometrists · Memphis, TN
- Gregory D. Parkhurst, M.D. Ophthalmology · San Antonio, TX
- Kyle M. Rhodes, MD Ophthalmology · Lakeway, TX
- Randy B. Carter, O.D. Optometrists · Salt Lake City, UT
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Eye Research Foundation, Inc $84,706
- Eye Doctors of Arizona $84,050
- Global Research Management Inc $76,763
- Total Eye Care, PA $76,256
- Red River Research PArtners $41,903
- Oculus Research, Inc. $37,648
- Mrb Eye Consultants, LLC $28,960
- Segal Drug Trials, Inc $27,044
- Price Vision Group $23,026
- Optometry Group PLLC $16,604
- Shettle Eye Research, Inc. $15,976
- Sabal Eye Care $15,850
- West Bay Eye Associates $15,510
- Gordon Schanzlin New Vision Institute $13,932
- Fraser Eye Care Center $13,534
- Kannar Eye Center $12,388
- Moyes Eye Center $10,335
- Pnv Clinical Research LLC $10,108
- Rochester Ophthalmological Group $9,900
- Durrie Vision $9,605
- Mid Florida Eye Center, P.a. $6,200
- Levenson Eye Associates $4,356
- Carrot Eye Center $4,053
- Lake Travis Eye and Laser Center / Revolution Research $3,007
- Lobue Laser and Eye Medical Center, Inc. $2,804
- The Eye Institute $2,058
- Wolstan & Goldberg Eye Associates $1,496
- Heart of America Eye Care, P.a $1,226
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.