Study on Biomarkers of Periodontitis and Type 2 Diabetes Mellitus in Males and Females 30 - 70 Years of Age
Completed · Not applicable · NCT06582056
Conditions: Periodontal Disease
At a glance
- Research payments reported, 2025
- $932,326
- U.S. investigators named
- 4
- Sites paid
- 5
- Planned or actual enrollment
- 226
About the trial
- Sponsor
- Sanofi Pasteur, a Sanofi Company
- Tested
- Investigational Procedure (procedure)
- Dates
- Started 2024-10-09; completion 2025-09-30
- Results posted
- Not yet
The purpose of this study is to learn about the interactions of markers of type 2 diabetes (T2DM) and periodontitis (PD). Study VPE00001 is a multi-center cross-sectional study. Participants will be categorized based on point-of-care hemoglobin A1c (HbA1c) and periodontal disease (PD) staging into 9 subgroups. The key objectives of the study are: * To evaluate immune signatures in well-characterized populations with or without PD and/or T2DM * To evaluate baseline clinical biomarkers of T2DM and PD in well-characterized populations * To evaluate the influence of clinical, immunological, and microbiological biomarkers on the bidirectional relationship between T2DM and PD
From ClinicalTrials.gov, last updated 2025-11-28. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Sanofi US Services Inc. reported $932,326 in research payments for this study in 2025 (15 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Sukirth M. Ganesan, BDS Periodontists · Iowa City, IA
- Hatice Hasturk, DDS, PH.D. Periodontists · Boston, MA
- Srinivas Rao Myneni Venkatasatya, DDS, PHD Periodontists · Stony Brook, NY
- Chun-teh Lee, DDS,MD,DMSC Dentists (general) · Houston, TX
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- The Research Found of State University of New York $310,865
- The University of Texas Health Scie Center at Houston $239,498
- Forsyth Institute $205,374
- University of Iowa Hospital & Clinics, IA $130,903
- The University of Texas Health Science Center at Houston $45,686
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.