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Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Moderate-to-Severe Plaque Psoriasis and Obesity or Overweight

Completed · Phase 3 · NCT06588283

Conditions: Psoriasis, Obesity

At a glance

Research payments reported, 2025
$7.3M
U.S. investigators named
75
Sites paid
90
Planned or actual enrollment
281

About the trial

Sponsor
Eli Lilly and Company
Tested
Ixekizumab (drug), Tirzepatide (drug)
Dates
Started 2024-09-30; completion 2026-06-01
Results posted
Not yet

The main purpose of this study is to demonstrate that when participants with moderate to severe plaque psoriasis and obesity or overweight in the presence of at least 1 weight-related comorbid condition receive ixekizumab and tirzepatide concomitantly administered, participants see improvement in their psoriasis and achieve weight reduction compared to when receiving ixekizumab. Participation in this study includes up to 12 visits and could last up to 61 weeks including screening, open label treatment period, and post-treatment follow-up period.

From ClinicalTrials.gov, last updated 2026-06-17. Full record, eligibility and contacts (opens in a new tab)

Industry funding

Eli Lilly and Company reported $7.3M in research payments for this study in 2025 (170 payments).

Products named: Taltz

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • Equity Medical LLC $507,700
  • The Indiana Clinical Trials Center PC $400,894
  • Care Access Research LLC $343,012
  • Delricht LLC $333,734
  • Sweet Hope Research Specialty Inc DBA Neoclinical Research $300,671
  • Oregon Medical Research Center PC $292,141
  • Mount Sinai School of Medicine $280,101
  • Dermatology Research Associates Inc $262,469
  • Progressive Clinical Research $240,994
  • Mindful Medical Research $227,492
  • Encore Medical Research, LLC $195,554
  • Oregon Dermatology and Research Center $174,546
  • Deluxe Health Center $154,816
  • Integrative Skin Science and Research $152,606
  • Phoenix Clinical Trials LLC $139,623
  • Cura Clinical Research LLC $132,619
  • Dr. Alma M Cruz Office $122,477
  • 113 Efficient Services $116,756
  • Scla Management LLC $116,456
  • Neurological Associates of Washington $106,072
  • Alliance for Multispecialty Research Lls $102,532
  • Texas Dermatology and Laser Specialists $101,468
  • Tcr Medical Corporation $100,077
  • Dawes Fretzin Clinical Research Group LLC $99,658
  • Skin Cancer and Der Inst -Reno $99,356
  • Virginia Clinical Research Inc $95,935
  • Gcm Medical Group Psc $91,957
  • Osman Dermatology $89,758
  • Renstar Inc $84,301
  • Avance Clinical Trials Inc $83,607
  • Northridge Clinical Trials $83,439
  • Southwest Skin Specialists LLC $82,990
  • Modern Research Associates PLLC $78,268
  • Stacy Smith MD Apc $76,683
  • Bellaire Dermatology Associates $71,112
  • Onsite Clinical Solutions LLC $70,813
  • Denova Research $70,393
  • Johnson Dermatology PLLC $68,340
  • Bellevue Dermatology Clinical Research $68,010
  • Red River Research PArtners $67,851
  • Palm Harbor Dermatology PA DBA Trueblue Clinical Research $63,973
  • Corazon USA LLC $61,589
  • Jerry Bagel MD LLC $61,422
  • Oak Dermatology $57,810
  • Dermatology Associates of Plymouth Meeting PC $57,165
  • Apex Clinical Trials LLC Suncoast Holdings Target LLC $55,305
  • The Derm Institute of West Michigan $53,244
  • Allcutis Research LLC $50,254
  • Nodal Medical Center $50,035
  • $47,621
  • Scb Research Center Corp $46,268
  • Lawrence J Green MD LLC $36,368
  • Great Lakes Research Group Inc $34,305
  • Total Skin and Beauty Dermatology Center PC $28,251
  • Palm Harbor Drmtlgy PA $28,238
  • Eximia Research Acquisition Ho $27,212
  • Dermassociates PC $26,822
  • Las Vegas Dermatology $25,734
  • Steven A Davis M D $20,181
  • Columbia Dermatology $16,110
  • Tanner Memorial Clinic DBA Tanner Clinic $14,102
  • Uh Cleveland Medical Center, OH $10,885
  • Apex Research Foundation LLC $9,436
  • Austin Institute for Clinical Research Inc $7,179
  • Tekton Research Inc $6,851
  • Capital Clinical Research Center PLLC $6,803
  • Univ of South Florida Rsrch Foundation $6,778
  • Mi Skin Innovations DBA Francisca Kartono $5,698
  • University of Utah Hospital and Clinics, UT $4,695
  • International Clinical Research $4,608
  • Skin Care Research Inc $3,984
  • Driscoll Childrens Hospital, TX $3,929
  • Therapeutics Clinical Research $3,828
  • Advanced Medical Research LLC $3,603
  • Dermatology Research Ventures LLC $3,430
  • Mehrdad Kevin Ariani MD $3,278
  • Renstar Medical Research $3,191
  • Hospital Universitario De Adulto, PR $2,891
  • Dermatologists of Southwest Ohio Inc $2,771
  • Tien Q Nguyen MD Inc DBA First Oc Dermatology $2,674
  • Emkey Arthritis and Osteoporosis $2,495
  • Solutions Through Advanced Research $2,418
  • Clinical Research Institute LLC $1,939
  • Avance Trials $1,777
  • Central Florida Regional Hospital $1,406
  • Allcutis Research Inc $1,163
  • Dermatology and Skin Cancer Specialists LLC $1,085
  • Yuma Clinical Trials LLC $1,085
  • Jdr Dermatology Research $1,085
  • Optima Research - Boardman $614
  • Activmed Practices and Research Inc $2

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.