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Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Psoriatic Arthritis and Obesity or Overweight

Completed · Phase 3 · NCT06588296

Conditions: Psoriatic Arthritis, Obesity

At a glance

Research payments reported, 2025
$7.2M
U.S. investigators named
88
Sites paid
76
Planned or actual enrollment
279

About the trial

Sponsor
Eli Lilly and Company
Tested
Ixekizumab (drug), Tirzepatide (drug)
Dates
Started 2024-09-24; completion 2026-04-23
Results posted
Not yet

The main purpose of this study is to demonstrate that when participants with psoriatic arthritis and obesity or overweight in the presence of at least 1 weight-related comorbid condition receive ixekizumab and tirzepatide concomitantly administered, participants see improvement in their psoriatic arthritis and achieve weight reduction compared to when receiving ixekizumab. Participation in this study includes up to 12 visits and could last up to 61 weeks including screening, open label treatment period, and post-treatment follow-up period.

From ClinicalTrials.gov, last updated 2026-05-13. Full record, eligibility and contacts (opens in a new tab)

Industry funding

Eli Lilly and Company reported $7.2M in research payments for this study in 2025 (188 payments).

Products named: Taltz

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • Arizona Arthritis and Rheumatology Research $955,063
  • Biovin Enterprises LLC $576,761
  • Clinical Research of West Florida Inc $331,766
  • Conquest Research LLC $239,724
  • Dynamed Clinical Research LP, DBA Dm Clinical Research $236,294
  • Scla Management LLC $194,056
  • Physicians Research Collaboration $193,235
  • International Center for Research $188,187
  • West Texas Clinical Research $179,008
  • Accurate Clinical Research Inc $176,692
  • Sweet Hope Research Specialty Inc DBA Neoclinical Research $149,916
  • Klein and Associates MD PA $146,795
  • Arh Research LLC $146,650
  • Gcm Medical Group Psc $138,275
  • Overlake Arthritis and Osteoporosis Center $137,733
  • Mindful Medical Research $134,302
  • Altoona Center for Clinical Research PC $134,240
  • Amarilis Perez $133,988
  • St PAul Rheumatology PA $133,929
  • Flourish Research Acquisition LLC $130,883
  • Vida Clinical Research $126,392
  • Corazon USA LLC $126,158
  • "southwest Rheumatology, P.a." $112,131
  • Essential Medical Research LLC $110,800
  • Albuquerque Center for Rheumatology $110,302
  • Clinical Investigation Specialists Inc $104,507
  • Southeastern Rheumatology Alliance DBA Arthritis Center of North Georgia $100,759
  • Qualmedica Research LLC $93,071
  • Precision Comprehensive Clinic $92,186
  • Paramount Medical Research and Consulting $89,835
  • Newport Huntington Medical Group $89,734
  • Reuviva Research Center LLC $86,613
  • Atlanta Research Center for $86,368
  • Rheumatology and Pulmonary Clinic $80,363
  • Logan Health Medical Center, MT $79,578
  • Vitalia Medical Research $77,167
  • Biopharma Informatic Inc $76,498
  • West Tennesse Research Institute $74,075
  • Rheumatology Center of San Diego PC $72,728
  • 121 Domenech Ave $67,554
  • Biopharma Informatic Inc Research Center $66,534
  • Onsite Clinical Solutions LLC $59,855
  • Rao Research LLC $54,412
  • Weitzner Yonker Kaine MD PA $53,011
  • Purushotham and Akther Kother, MD, Inc $49,894
  • Alliance for Multispecialty Research Lls $46,020
  • Tekton Research Inc $39,267
  • Djl Clinical Research PLLC $32,333
  • Advanced Rheumatology PC $27,665
  • Arthritis Northwest PLLC $25,259
  • St Luke's Regional Medical Center, ID $24,456
  • Suncoast Clinical Research $21,697
  • Denver Arthritis Clinic PC $21,314
  • Trinity Universal Research Associates Inc $20,700
  • Aara Clinical Research $20,035
  • Clinvest Headlands LLC $18,852
  • Neccr Prima Care Research LLC $17,263
  • Summit Headlands LLC $16,948
  • St Lawrence Health System Inc $16,551
  • $16,302
  • Hillary E. Norton MD PC $13,236
  • Driscoll Childrens Hospital, TX $3,717
  • Bingham Memorial Hospital $3,500
  • Dr Amir Hassan $3,388
  • Tamar Brionez $3,157
  • Clayton Medical Associates PC $3,038
  • Long Island Jewish Medical Center, NY $2,466
  • Acn Research LLC $2,406
  • Arthritis Consultants Inc $2,346
  • Great Lakes Medical Research LLC $2,231
  • Low Country Rheumatology PA $1,455
  • Moffitt Cancer Center $1,247
  • Hoag Memorial Hospital Presbyterian $728
  • Crowley Core LLC $445
  • Dana-Farber Cancer Institute $291
  • Clinvest Research LLC $52
  • Great Lakes Clinical Trials $4

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.