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A Study to Investigate the Safety and Efficacy of mRNA-1403 in Participants ≥18 Years of Age for the Prevention of Acute Gastroenteritis

Active, not recruiting · Phase 3 · NCT06592794

Conditions: Acute Gastroenteritis, Norovirus Acute Gastroenteritis

At a glance

Research payments reported, 2025
$117.0M
U.S. investigators named
186
Sites paid
216
Planned or actual enrollment
37,864

About the trial

Sponsor
ModernaTX, Inc.
Tested
mRNA-1403 (biological), Placebo (biological)
Dates
Started 2024-09-24; completion 2027-02-15
Results posted
Not yet

The primary objectives of this study are to evaluate the safety and reactogenicity of mRNA-1403, and to demonstrate the efficacy of mRNA-1403 to prevent protocol-defined moderate or severe norovirus acute gastroenteritis (AGE) associated with vaccine matched genotypes.

From ClinicalTrials.gov, last updated 2026-05-13. Full record, eligibility and contacts (opens in a new tab)

Industry funding

ModernaTX, Inc. reported $117.0M in research payments for this study in 2025 (10,028 payments).

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • Velocity Clinical Research Inc $13.4M
  • Elias Research Associates LLC $7.2M
  • Dynamed Clinical Research LP $5.4M
  • Interspond LLC $3.9M
  • Javara Inc $3.6M
  • Delricht Research $3.0M
  • Cenexel Clinical Research Inc $2.8M
  • Sweet Hope Research Speciality Inc $2.7M
  • Qcare Site Services Inc $2.7M
  • Precision Clinical Research LLC $2.4M
  • Tekton Research LLC $2.3M
  • Clinical Neuroscience Solutions Inc $2.0M
  • Clinical Research of Broward $1.8M
  • Accellacare US Inc $1.8M
  • West Houston Clinical Research Service $1.7M
  • Headlands Horizons LLC $1.7M
  • Imagine Research of PAlm Beach County $1.7M
  • Pioneer Clinical Studies $1.5M
  • Clinical Trials Management LLC $1.5M
  • Acrc Trials $1.4M
  • Quality of Life Medical and Research Centers LLC $1.4M
  • Clinical Research PArtners LLC $1.4M
  • Drug Trials America Inc $1.3M
  • Ima Evaluations LLC DBA Ima Clinical Research $1.3M
  • Swift Clinical Opco Inc $1.2M
  • Johnson County Clintrials LLC $1.2M
  • Clinical Research Institute Inc $1.2M
  • Dynamed Philadelphia LLC $1.2M
  • Dynamed Washington LLC $1.2M
  • Health Awareness LLC $1.2M
  • Research Your Health LLC $1.1M
  • Del Sol Research Management LLC $1.1M
  • Integrity Clinical Research, LLC $1.1M
  • Paradigm Clinical Research Centers LLC $1.0M
  • Hope Research Institute LLC $1.0M
  • Dynamed Detroit LLC $1.0M
  • West Clinical Research Inc $988,984
  • Achieve Clinical Research LLC $947,536
  • Health Research of Hampton Roads Inc $911,477
  • Universal Axon Clinical Research LLC $880,548
  • University Clinical Research Deland LLC $871,869
  • Brcr Medical Center Inc $856,471
  • Sandhill Research LLC $826,686
  • Community Research Management Associates Inc $821,158
  • Cra Headlands LLC $793,621
  • Dynamed New Mexico LLC $783,932
  • Alliance for Multispecialty Research LLC $777,918
  • Global Clinical Professionals LLC $777,033
  • Dynamed Chicago LLC $768,898
  • The Institute for Liver Health LLC $767,403
  • Clinical Research Professionals $758,281
  • Texas Center for Drug Development Inc $749,766
  • Dm Boston LLC $747,202
  • Coastal Carolina Research Center Inc $723,804
  • Jacksonville Center for Clinical Research $720,015
  • Charlottesville Medical Research Center LLC $712,209
  • Artemis Headlands LLC $706,796
  • Baptist Health Center for Clinical Research LLC $664,900
  • Neostart Corporation $654,332
  • Skylight Health Research Inc $636,041
  • Ark Clinical Research LLC $620,064
  • Scottsdale Clinical Trials $602,368
  • Bioluminux Clinical Research Illinois LLC $596,820
  • Clinical Site PArtners Inc $595,893
  • Matrix Clinical Research Inc $592,690
  • Clinical Research Prime Idaho Falls LLC $587,730
  • United Medical Research LLC $570,330
  • Oasis Clinical Research LLC $527,688
  • Suncoast Research Associates LLC DBA Sra Trials $519,454
  • M3 Wake Research Inc $503,787
  • Wake Forest University Health Sciences $502,405
  • Dynamed Arizona LLC $493,511
  • Suncoast Clinical Research LLC $468,386
  • Miami Dade Medical Research Institute, LLC $460,667
  • Lynn Health Science Institute Inc $444,636
  • Cr Services Acquisition US LLC $441,225
  • Peninsula Headlands LLC $437,997
  • Clinvest Headlands LLC $435,951
  • Dynamed New Jersey LLC $433,790
  • Rochester Clinical Research LLC $433,041
  • Glri El PAso Research LLC $425,830
  • Remington Davis Inc $380,549
  • Researchworkspuertorico $374,867
  • Synexus Clinical Research US Inc $374,248
  • Great Lakes Clinical Trials LLC $373,210
  • Great Lakes Research Institute LLC $344,283
  • Bioluminuxclinicalresearchillinoisllc $332,751
  • Las Vegas Medical Research LLC $326,778
  • Florida International Research Center $277,936
  • Clinical Research Puerto Rico Inc $176,324
  • Lynn Institute of the Ozarks $160,622
  • Frontier Clinical Research LLC $156,081
  • Cullman Clinical Trials LLC $153,064
  • Altoona Center for Clinical Research PC $143,955
  • Aqualane Clinical Research $116,180
  • Miami Dade Medical Research Institute $91,499
  • Nature Coast Clinical Research $47,239
  • Jbr Clinical Research LLC $9,050
  • Cenexel Rocky Mountain Clinical Research LLC $5,375
  • Cenexel Iresearch LLC $3,000

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.