A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis
Active, not recruiting · Phase 2 · NCT06598943
Conditions: Ulcerative Colitis, Ulcerative Colitis Chronic
At a glance
- Research payments reported, 2025
- $891,548
- U.S. investigators named
- 38
- Sites paid
- 36
- Planned or actual enrollment
- 143
About the trial
- Sponsor
- Eli Lilly and Company
- Tested
- Eltrekibart (drug), Mirikizumab (drug), Placebo (drug)
- Dates
- Started 2024-10-10; completion 2027-07
- Results posted
- Not yet
The main purpose of this study is to determine the safety and efficacy of eltrekibart and mirikizumab in adult participants with moderately to severely active ulcerative colitis (UC).
From ClinicalTrials.gov, last updated 2026-10-07. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Eli Lilly and Company reported $891,548 in research payments for this study in 2025 (39 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- John T. Baber SR., MD Gastroenterology · Little Rock, AR
- Angelo G. Coppola JR., M.D. Gastroenterology · Little Rock, AR
- Jae H. Kim, M.D. Gastroenterology · Mesa, AZ
- Erick H. Alayo, M.D. Gastroenterology · Chula Vista, CA
- Amit Bhanvadia, M.D. Gastroenterology · Anaheim, CA
- Tarek Ezzeddine, MD Internal Medicine · Rancho Cucamonga, CA
- Tarek I. Hassanein, M.D. Hepatology · Coronado, CA
- Michael D. Kurtz, M.D. Gastroenterology · Oceanside, CA
- Seyedehsan Navabi, M.D. Gastroenterology · Murrieta, CA
- Thomas Thong H. Nguyen, M.D., Gastroenterology · Victorville, CA
- Mahendra N. Patel, M.D. Gastroenterology · Simi Valley, CA
- Jatinder S. Pruthi, M.D. Gastroenterology · Lancaster, CA
- Bhaktasharan C. Patel, MD Gastroenterology · Colorado Springs, CO
- Eddie Armas, MD General Practice · South Miami, FL
- Mina Elnemr, M.D. Gastroenterology · Tampa, FL
- Leopoldo Grauer, MD Gastroenterology · Tampa, FL
- Udayakumar Navaneethan, MD Gastroenterology · Saint Petersburg, FL
- Victor M. Pina, MD Gastroenterology · Miami, FL
- Manuel E. Rodriguez, M.D. Gastroenterology · Bradenton, FL
- Angel M. Rosario, MD Gastroenterology · Tampa, FL
- Jorge M. Venereo, M.D. Internal Medicine · Doral, FL
- Alan M. Weintraub, MD Gastroenterology · Tampa, FL
- Charles Berkelhammer, MD Specialist · Oak Lawn, IL
- Keith C. Summa, M.D., PH.D. Hospitalist · Chicago, IL
- David A. Dulitz, M.D. Gastroenterology · Luling, LA
- Allan G. Coates, DO Gastroenterology · Wyoming, MI
- Harvey H. Allen JR., MD Gastroenterology · Utica, NY
- Animesh Jain, M.D. Student in an Organized Health Care Education/Training Program · New York, NY
- Gulam M. Khan, MD Internal Medicine · Brooklyn, NY
- Murray Orbuch, M.D. Gastroenterology · New York, NY
- Pradeep Kumar T. Bekal, M.D. Gastroenterology · Cincinnati, OH
- Haider Afzal, MD Family Medicine · Baytown, TX
- S M. Badiga, MD Gastroenterology · Weslaco, TX
- George A. Duvall, M.D. Gastroenterology · Tyler, TX
- Jason K. Hou, M.D. Gastroenterology · Houston, TX
- Nicholas P. Martinez, M.D. Gastroenterology · San Antonio, TX
- Chad M. Gonzales, M.D. Gastroenterology · Ogden, UT
- John E. Lowe, MD Gastroenterology · Ogden, UT
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Gastroenterology Clinic of San Antonio $108,548
- Avicenna Clinical Research LLC $69,017
- Om Research LLC $62,405
- United Medical Doctors $54,973
- Peak Gastroenterology Associates $49,574
- Nodal Medical Center $45,477
- International Center for Research $42,885
- Well Pharma Medical Research Corp $32,808
- Clinnova Research Solutions Corporation $29,900
- Elias Research Associates LLC $25,866
- Ivam Clinical and Investigatio $25,456
- Pioneer Clinical Research Ny $23,772
- Reserka LLC $23,490
- Tyler Research Institute LLC $21,938
- Applied Research Center of Arkansas $20,500
- Dhr Health Institute for Resea $20,350
- Baptist Health $18,361
- Northwestern University $17,556
- Orlando Health, FL $17,500
- Baylor College of Medicine $16,750
- Advanced Research Inc $16,321
- Clinical Trials Management Services LLC $14,500
- Gcga Physicians Inc DBA Consultants for Clinical Res $14,500
- Erick H Alayo Medical Corporate $13,500
- Az Gastro Care $13,450
- Valley View Research $13,400
- Digestive Disease Medicine of Central New York $13,000
- Florida Digestive Health Specialists LLP $12,640
- Clinical Trials Management LLC $12,000
- Research Bay Inc $11,650
- Southern California Research Center $10,000
- Prospective Research Innovations Inc $7,705
- University of North Carolina at Chapel Hill $2,740
- Care Access Research LLC $2,685
- Smart Medical Research Inc $2,168
- $2,163
- Gastroenterology Associates of Western $2,000
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.