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A Study of mRNA-1010 Compared With a Licensed Influenza Vaccine in Adults ≥50 Years of Age

Completed · Phase 3 · NCT06602024

Conditions: Seasonal Influenza

At a glance

Research payments reported, 2025
$83.4M
U.S. investigators named
188
Sites paid
90
Planned or actual enrollment
40,805

About the trial

Sponsor
ModernaTX, Inc.
Tested
mRNA-1010 (biological), Fluarix® (biological), Influsplit® Tetra (biological), Fluarix Tetra (biological), Alpharix® Tetra (biological)
Dates
Started 2024-09-16; completion 2025-08-21
Results posted
Yes

The primary objectives of this study are to evaluate the safety and reactogenicity of mRNA-1010, and to evaluate relative vaccine efficacy (rVE) of mRNA-1010 versus an active comparator against reverse transcription polymerase chain reaction (RT-PCR)-confirmed protocol-defined influenza-like illness (ILI) caused by any influenza A or B strains.

From ClinicalTrials.gov, last updated 2026-09-16. Full record, eligibility and contacts (opens in a new tab)

Industry funding

ModernaTX, Inc. reported $83.4M in research payments for this study in 2025 (5,004 payments).

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • Velocity Clinical Research Inc $11.2M
  • M3 Wake Research Inc $9.8M
  • Delricht Research $4.3M
  • Dynamed Clinical Research LP $3.1M
  • Javara Inc $3.0M
  • Ima Evaluations LLC DBA Ima Clinical Research $2.7M
  • Tekton Research LLC $2.2M
  • Headlands Horizons LLC $1.7M
  • Helios Cr Inc $1.7M
  • The Institute for Liver Health LLC $1.5M
  • Cr Services Acquisition US LLC $1.3M
  • Miami Clinical Research Lllp $1.2M
  • Artemis Headlands LLC $1.2M
  • J Lewis Research Inc $1.1M
  • Jacksonville Center for Clinical Research $1.1M
  • Cra Headlands LLC $1.0M
  • Elias Research Associates LLC $994,010
  • Accellacare US Inc $942,122
  • Suncoast Research Associates LLC DBA Sra Trials $920,476
  • Dm Boston LLC $897,479
  • Rochester Clinical Research LLC $861,218
  • Floridian Clinical Research LLC $854,790
  • Sweet Hope Research Speciality Inc $840,360
  • Clinical Research PArtners LLC $827,699
  • Health Awareness LLC $797,566
  • Texas Center for Drug Development Inc $791,169
  • Qcare Site Services Inc $790,134
  • Eximia Research Nc LLC $785,583
  • Cenexel Iresearch LLC $774,892
  • Spartanburg Medical Research LLC $742,646
  • Clinical Research Professionals $740,365
  • Summit Headlands LLC $728,420
  • Paradigm Clinical Research Centers LLC $699,378
  • Tma Headlands LLC $692,507
  • Central Washington Health Services Association $679,783
  • Dynamed Detroit LLC $675,612
  • Baptist Health Center for Clinical Research LLC $664,610
  • Valley Clinical Trials Inc $612,759
  • Alliance for Multispecialty Research LLC $607,965
  • Dynamed Philadelphia LLC $604,527
  • Dynamed Chicago LLC $601,408
  • Emvenio Research Inc $576,393
  • Clinvest Headlands LLC $538,623
  • Sundance Clinical Research LLC $537,183
  • Long Beach Research Institute $534,959
  • Dynamed New Jersey LLC $532,273
  • Johnson County Clintrials LLC $504,748
  • Peninsula Headlands LLC $502,915
  • Trial Management Associates LLC $479,024
  • David Fitz-Patrick MD Inc $475,453
  • Sandhill Research LLC $468,516
  • Forward Clinical Trials Inc $442,688
  • K2 Medical Research LLC $442,512
  • Chase Medical Research LLC $442,184
  • Boeson Research LLC $423,434
  • Jem Headlands LLC $412,713
  • Clinical Site PArtners Inc $396,767
  • North Alabama Research Center LLC $392,736
  • Erg Holding Company LLC $389,534
  • Cognitive Clinical Trials LLC $388,774
  • Great Lakes Research Institute LLC $378,997
  • Diablo Clinical Research Inc $375,991
  • Henderson Clinical Trials LLC $371,517
  • Carbon Health Technologies Inc $371,386
  • Health Research of Hampton Roads Inc $337,616
  • Stamford Therapeutics Consortium $336,682
  • Jbr Clinical Research LLC $327,599
  • Dynamed New Mexico LLC $327,563
  • Central Research Associates Inc $313,505
  • Research Your Health LLC $302,406
  • Dynamed Arizona LLC $299,845
  • Cbh Health LLC $272,902
  • Nature Coast Clinical Research $268,947
  • Synexus Clinical Research US Inc $261,413
  • Community Research Management Associates Inc $259,400
  • Asheville Clinical Research LLC $255,124
  • Bmh Inc $251,654
  • Newco 3a Research LLC DBA 3a Research $239,249
  • Wake Forest University Health Sciences $226,387
  • Cullman Clinical Trials LLC $226,277
  • Pinnacle Research Group LLC $215,804
  • The Corvallis Clinic PC $208,783
  • Preferred Primary Care Physicians Inc $140,020
  • Research Centers of America LLC $139,898
  • Multispecialty Clinical Research Inc $121,792
  • Great Lakes Clinical Trials LLC $114,660
  • Amherst Family Practice $97,880
  • Axces Research Group LLC $69,986
  • Black Hills Center for American Indian Health $32,871

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.