A Study of LY4100511 (DC-853) in Adult Participants With Moderate-to-Severe Plaque Psoriasis
Completed · Phase 2 · NCT06602219
Conditions: Plaque Psoriasis
At a glance
- Research payments reported, 2025
- $1.3M
- U.S. investigators named
- 13
- Sites paid
- 13
- Planned or actual enrollment
- 222
About the trial
- Sponsor
- DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company
- Tested
- LY4100511 (drug), Placebo (drug)
- Dates
- Started 2024-10-25; completion 2025-09-04
- Results posted
- Yes
The main purpose of this study is to assess the safety and efficacy of LY4100511 in adult participants with moderate-to-severe plaque psoriasis.
From ClinicalTrials.gov, last updated 2026-08-18. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Eli Lilly and Company reported $1.3M in research payments for this study in 2025 (13 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Vlada Groysman, MD Dermatology · Hoover, AL
- Dowling B. Stough IV, MD Dermatology · Hot Springs, AR
- Sunil S. Dhawan, MD Dermatology · Fremont, CA
- Vivian Laquer, M.D. Dermatology · Irvine, CA
- Howard L. Sofen, M.D. Dermatology · Los Angeles, CA
- David M. Stoll, M.D. Specialist · Beverly Hills, CA
- Javier Alonso-llamazares, M.D.PHD. Dermatology · Coral Gables, FL
- Ashley Cauthen, M.D. Dermatology · Ocala, FL
- Frank A. Don, D.O. Dermatology · Hallandale Beach, FL
- Seth B. Forman, MD Dermatology · Tampa, FL
- Stephanie Mehlis, M.D. Dermatology · Skokie, IL
- Lawrence J. Green, MD Dermatology · Rockville, MD
- Stephen K. Tyring, MD PHD Dermatology · Webster, TX
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Direct Helpers Medical Center $393,359
- Driven Research LLC $212,746
- Cahaba Dermatology and Skin Health Center LLC $160,974
- Dermatology Trial Associates $151,176
- 113 Efficient Services $82,689
- Center for Dermatology Clinical Research Inc $74,418
- Dermatology Research Associates Inc $53,759
- Center for Clinical Studies LTD LLP $49,911
- Lawrence J Green MD LLC $32,488
- Renstar Inc $27,125
- Northshore University Healthsystem - Evanston Hospital, IL $25,860
- Zenith Research Inc $6,375
- Forward Clinical Trials Inc $2,250
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.