A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus
Recruiting · Phase 3 · NCT06617325
Conditions: Systemic Lupus Erythematosus
At a glance
- Research payments reported, 2025
- $1.6M
- U.S. investigators named
- 52
- Sites paid
- 82
- Planned or actual enrollment
- 450
About the trial
- Sponsor
- UCB Biopharma SRL
- Tested
- DZP (drug), Placebo (other)
- Dates
- Started 2024-11-21; completion 2028-05-31
- Results posted
- Not yet
The purpose of this study is to evaluate the ability of dapirolizumab pegol (DZP) as an add-on treatment to standard of care (SOC) medication to achieve clinically relevant long term improvement of moderate to severe disease activity.
From ClinicalTrials.gov, last updated 2026-11-02. Full record, eligibility and contacts (opens in a new tab)
Industry funding
UCB SA reported $1.6M in research payments for this study in 2025 (107 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Shailendra Singh, M.B.B.S. Rheumatology · Searcy, AR
- Amer Al-khoudari, M.D. Rheumatology · Chandler, AZ
- Swati S. Bharadwaj, MD, MPH Rheumatology · Phoenix, AZ
- Rajat K. Dhar, MD Rheumatology · Glendale, AZ
- Matthew Herrmann, M.D. Rheumatology · Phoenix, AZ
- Sheetal R. Desai, MD Rheumatology · Orange, CA
- Gerald Y. Ho, M.D. Rheumatology · La Palma, CA
- Kenneth C. Kalunian, MD Rheumatology · San Diego, CA
- Rebekah A. Neal-kraal, M.D. Rheumatology · Los Alamitos, CA
- C. Michael Neuwelt, M.D. Rheumatology · San Leandro, CA
- Michael R. Bubb, MD Rheumatology · Gainesville, FL
- Lance Feller, M.D. Rheumatology · Lake Mary, FL
- Julio Gonzalez-paoli, MD Rheumatology · Tampa, FL
- Vipul M. Joshi, MD Specialist · Brandon, FL
- Robert Levin, MD Internal Medicine · Wellington, FL
- Layla B. Mcdaniel, PA-C Physician Assistants · Jacksonville, FL
- Jose C. Pinero, M.D. Hospitalist · Miami, FL
- Jorge L. Posada, MD Nephrology (Kidney) · Coral Gables, FL
- Jigar Shah, M.D. Rheumatology · Margate, FL
- Guillermo J. Valenzuela, MD Specialist · Plantation, FL
- Brent A. Flickinger, MD Rheumatology · Gainesville, GA
- Roel N. Querubin, M.D. Rheumatology · Marietta, GA
- Angela R. Crowley, M.D. Rheumatology · Willowbrook, IL
- Dennis J. Levinson, M.D. Internal Medicine · Chicago, IL
- Himabindu B. Reddy, M.D. Physical Medicine & Rehabilitation (PM&R) · Glenview, IL
- Housam A. Sarakbi, MD Rheumatology · Louisville, KY
- Stephen M. Lindsey, M.D. Rheumatology · Baton Rouge, LA
- Enrique A. Mendez, M.D. Rheumatology · Lake Charles, LA
- Evan L. Siegel, M.D. Rheumatology · Rockville, MD
- Ilyes Benchaala, MD Rheumatology · Detroit, MI
- David E. Burdette, MD Neurology · Grand Rapids, MI
- Ghaith Noaiseh, MD Rheumatology · Kansas City, MO
- Tina Shah, MD Rheumatology · Kansas City, MO
- Alexander J. Lim, MD Anesthesiology · High Point, NC
- Cynthia Aranow, M.D. Rheumatology · Manhasset, NY
- David H. Goddard, MD Rheumatology · Brooklyn, NY
- Kyriakos A. Kirou, M.D. Specialist · New York, NY
- Andras Perl, MD Rheumatology · Syracuse, NY
- Andreea Coca, MD Rheumatology · Pittsburgh, PA
- Alan Kivitz, MD Rheumatology · Duncansville, PA
- Sabrina S. Yum, MD Child Neurology · Philadelphia, PA
- Jacob Aelion, M.D. Specialist · Jackson, TN
- Marcus A. Owen, MD Rheumatology · Murfreesboro, TN
- Ranjit K. Dhelaria, MD Nephrology (Kidney) · Denton, TX
- Michelle Eisenberg, D.O. Rheumatology · Houston, TX
- Saba Khan, M.D. Rheumatology · Sugar Land, TX
- Rama R. Palwai, M.D. Rheumatology · Spring, TX
- Sunny Patel, MD Rheumatology · Red Oak, TX
- Megha Patel-banker, MD Rheumatology · Allen, TX
- Nirav Pavasia, M.D. Neurology · Dallas, TX
- Atul K. Singhal, M.D. FACR Rheumatology · Mesquite, TX
- Wajeeha Yousaf, MD Rheumatology · Houston, TX
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Arizona Arthritis and Rheumatology Research $192,279
- Professional Research Center Inc $185,090
- Advanced Medical Research $85,523
- International Center for Research $64,812
- Novel Research Llc $63,211
- Lsu Health Sciences Center $52,360
- 1960 Family Practice, PA $47,627
- University of California San Diego Jacobs Medical Center $47,625
- Valerius Medical Group and Research Center $45,481
- Pediatric Neurology PA $42,672
- Research Foundation of Suny $41,730
- Prolato Clinical Research Center $41,074
- Medvin Clinical Research $40,226
- C.v. Mehta M.d. Medical Corp. $33,879
- Conquest Research, Llc $32,784
- Chicago Clinical Research Institute $29,711
- University of Pittsburgh Physicians $28,800
- Care and Cure Clinic $25,163
- Elias Research Associates $24,368
- Ku Infectious Disease $24,169
- Arizona Arthritis and Rheumatology Associates, PC $22,875
- Willow Rheumatology and Wellness $22,514
- Lake Cumberland Rheumatology, PLLC $19,923
- Unity Health $19,921
- Arizona Arthritis and Rheumatology Associates - Phoenix $16,936
- Corazon USA LLC $16,250
- Wayne State University $16,172
- Millennium Medical Research LLC $15,495
- Southeastern Rheumatology Alliance $14,608
- University of Louisville Research Foundation Inc $14,105
- Murfreesboro Medical Clinic $13,069
- Weitzner, Yonker, Kaine MD. $13,000
- Spring Clinical Research $13,000
- Accurate Clinical Research, Inc. $12,661
- Arthritis Center of North Georgia LLC $12,661
- C V Mehta MD Medical Corp $12,075
- Atlanta Research Center for Rheumatology LLC $11,550
- Vipul Joshi MD PA $11,428
- Precision Comprehensive Clinical Research Solutions, LLC $11,155
- Lake Cumberland Rheumatology PLLC $10,500
- Uci Health-Orange, CA $9,888
- Ochsner Medical Center Acute, LA $9,600
- Hope Clinical Trials Inc $9,500
- Arthritis and Rheumatism Associates, P.c. $9,108
- Kansas City Physician PArtners, in $9,074
- $8,695
- Suny Upstate Medical University - Medicine $8,622
- Allied Biomedical Research Institute $8,583
- Prime Clinical Research Inc. $8,331
- Lone Star Arthritis & Rheuma Assoc $8,324
- University of Colorado - School of Medicine - Rheumatology $8,303
- University of Kansas Medical Center - Rheumatology $8,301
- Radiation Oncology Gilbert $8,294
- Bay Area Arthritis and Osteoporosis $7,972
- Arthritis & Osteoporosis Medical Center Inc. - La PAlma $7,963
- Millennium Medical Research, LLC Clinical Research $7,875
- Uf Health Rheumatology $7,875
- New York University Medical Center $7,124
- Accurate Clinical Research Inc $7,000
- Epic Medical Research, LLC $5,170
- Kidney Disease Program $4,935
- Wayne State University, Cs Mott Center for Human Growth and Development $4,275
- Marietta Rheumatology Associates, PC $3,480
- Professional Research Center $1,426
- Atlanta Center for Clinical Research $720
- University of Florida $720
- Hospital for Special Surgery $638
- Hospital for Special Surgery, NY $338
- Arthritis & Rheumatology Rsrch Inst $320
- University of California San Diego, Perlman Medical Offices $299
- Precision Comprehensive Clinical Research Solutions $244
- Aara Clinical Research $239
- Intergral Rheumatology & Immunology Specialist $181
- Arthritis Center of North Georgia $125
- Chicago Clinical Research Institute - Medical Research $122
- Joseph S. and Diane H. Steinberg Ambulatory Care Center $121
- Feinstein Institutes for Medical Research $119
- Arthritis & Osteoporosis Medical Center, Inc. - La PAlma $107
- Southwest Rheumatology Research LLC $61
- Long Island Jewish Medical $60
- West Tennessee Research Institute $1
- Clinical Research of West Florida $1
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.