A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults
Active, not recruiting · Phase 2 · NCT06625060
Conditions: Episodic Migraine, Chronic Migraine
At a glance
- Research payments reported, 2025
- $1.7M
- U.S. investigators named
- 36
- Sites paid
- 42
- Planned or actual enrollment
- 670
About the trial
- Sponsor
- Ipsen
- Tested
- Corabotase (biological), Placebo (other), Corabotase dose A (biological), Corabotase dose B (biological)
- Dates
- Started 2024-10-10; completion 2027-10-31
- Results posted
- Not yet
A migraine is a headache with severe throbbing pain or a pulsating sensation, usually on one side of the head. It is often accompanied by feeling or being sick and a sensitivity to bright lights and sound. Migraines are caused by a series of events when the brain gets stimulated or activated, which causes the release of chemicals that cause pain. Corabotase (also known as IPN10200) is a medication that stops the release of these chemical messengers. Participants with episodic migraine (EM) or chronic migraine (CM) will be included in both Step 1 and Step 2. "Headache days" are when participants experience headaches that meet the criteria for a migraine or a headache without the additional…
From ClinicalTrials.gov, last updated 2026-09-08. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Ipsen Innovation reported $1.7M in research payments for this study in 2025 (822 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Belinda A. Savage-edwards, M.D. Specialist · Huntsville, AL
- Hemant K. Pandey, MD Neurology · Chandler, AZ
- Hossein Ansari, M.D. Neurology · San Diego, CA
- Perminder Bhatia, MD Neurology · Fresno, CA
- Clifford R. Feldman, M.D, J.D., M.F.S. Psychiatry · Tarzana, CA
- Benjamin M. Frishberg, M.D. Neurology · Carlsbad, CA
- Ashkan Mowla, M.D Neurology · Los Angeles, CA
- Alberto J. Odio, M.D. Family Medicine · Simi Valley, CA
- Arbi Ohanian, M.D. Neurology · Pasadena, CA
- Tamara A. Miller, M.D. Specialist · Fort Collins, CO
- Ning S. Yang Neurology · Johnstown, CO
- Ernesto Alonso, MD Neurology · Lake City, FL
- David M. Bear, D.O. Neurology · Pensacola, FL
- Brian A. Costell, M.D. Neurology · Boca Raton, FL
- Rekha Gandhi, MD Neurology · Winter Park, FL
- Anette Nieves, MD Neurology · Ocala, FL
- Matthews W. Gwynn, M.D. Neurology · Atlanta, GA
- Brian J. Copeland, MD Neurology · New Orleans, LA
- Patrick M. Dennis, MD Emergency Medicine · New Orleans, LA
- Carol R. Redillas, MD Neurology · Chalmette, LA
- Maria Carmen Wilson, MD Neurology · Covington, LA
- Shathabish Kariyanna, MD Family Medicine · Ann Arbor, MI
- Harmony A. Sierens, M.D. Physical Medicine & Rehabilitation (PM&R) · Grand Blanc, MI
- Chad A. Whyte, M.D. Neurology · Omaha, NE
- Robby Ann Quintos, MD Internal Medicine · Las Vegas, NV
- Richard B. Lipton, MD Neurology · Bronx, NY
- Gary Volkell Neurology · Albany, NY
- James E. Wild, M.D. Family Medicine · Gowanda, NY
- Inna N. Yuryev-golger, MD Psychiatry · Brooklyn, NY
- Joel Vandersluis, M.D. Neurology · Dayton, OH
- Nathan L. Bennett, M.D. Family Medicine · Pittsburgh, PA
- Lora J. Mcgill, M.D. Neurology · Memphis, TN
- Maria G. Berdayes, DO Family Medicine · Kingwood, TX
- Amro El Feki, MD Neurology · Webster, TX
- Sefanit Gebretsadik, M.D Internal Medicine · Frisco, TX
- Patrick J. Hogan III, D.O. Neurology · Tacoma, WA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- M3 Wake Research $173,151
- Clinical Neuroscience Solutions, Inc $136,340
- Integrative Clinical Trials $131,764
- Trialsphere Clinical Research $130,952
- Dr Bhatias Neuropain Medical Center $113,274
- Profound Research LLC $111,743
- Wake Research Associates $101,540
- Ki Health PArtners, Llc $94,935
- Delricht Research $84,041
- Clinical Trials Management Services $83,821
- Advanced Neurosciences Research, Llc $78,527
- Preferred Primary Care Physicians, Inc $75,070
- Michigan Headache and Neurological Institute $64,380
- Neurology Diagnostics, Inc $38,045
- Upstate Clinical Research Associates $31,861
- $31,519
- Conquest Research, Llc $25,500
- Biomedical Research Alliance of New York $24,780
- Neurology Offices South Florida $21,509
- Kaizen Brain Center $20,800
- Louisiana State University Health Sciences Center New Orleans $19,181
- Alliance Clinical Network $18,050
- Elevate Clinical Research $14,400
- Medical Rehabilitation Group, PC $3,868
- Emerald Coast Center for Neurological Disorders $3,611
- Neurotrials Research $3,611
- Javara, Inc $3,485
- Rehabilitation & Neurological Services, LLC $3,485
- Renstar Medical Research $3,485
- Ochsner Health Center for Children $3,485
- Puget Sound Neurology and Integrative Headache Center $2,211
- The Neurology Center of Southern California $2,211
- Southern California Neurology $419
- Medstar Health at Brandywine Neurology $381
- Wr-Pri Encino $126
- Medstar Franklin Square Medical Center $126
- Lsu Healthcare Network $126
- Montefiore Medical Center $126
- Cns Healthcare $126
- M3 Wake Research Los Alamitos $126
- Zenos Clinical Research $41
- Cct Research PApillion Research Center $41
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.