Study to Evaluate Immunogenicity and Safety of a High-Dose Influenza Vaccine in Adults 50 Through 64 Years of Age
Completed · Phase 3 · NCT06641180
Conditions: Influenza
At a glance
- Research payments reported, 2025
- $2.8M
- U.S. investigators named
- 21
- Sites paid
- 13
- Planned or actual enrollment
- 1,180
About the trial
- Sponsor
- Sanofi Pasteur, a Sanofi Company
- Tested
- High-Dose trivalent influenza vaccine (Split virion, Inactivated) (biological), Standard-dose trivalent influenza vaccine (Split virion, Inactivated) (biological)
- Dates
- Started 2024-11-04; completion 2025-06-24
- Results posted
- Not yet
The purpose of this study is to evaluate Immunogenicity and Safety of a High-Dose (HD) Influenza Vaccine (IV) in Adults 50 through 64 Years of Age.
From ClinicalTrials.gov, last updated 2025-12-03. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Sanofi Pasteur Inc. reported $2.8M in research payments for this study in 2025 (111 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Todd Bertoch, M.D. Anesthesiology · Prescott, AZ
- Steven H. Reynolds, D.O. Family Medicine · Long Beach, CA
- Nelia E. Sanchez-crespo, M.D. Internal Medicine · Hollywood, FL
- Pedro P. Ylisastigui, M.D. Internal Medicine · Lehigh Acres, FL
- Yael R. Elfassy, M.D. Pediatrics · Savannah, GA
- Kimball A. Johnson, MD Internal Medicine · Atlanta, GA
- Maria C. Mascolo, MD Pulmonology · Rincon, GA
- Nadine G. Rouphael, M.D. Infectious Disease · Atlanta, GA
- Joseph G. Surber, DO Family Medicine · Columbus, GA
- Troy A. Holdeman, MD Family Medicine · Newton, KS
- Mark S. Adams, M.D. Internal Medicine · London, KY
- Elia E. Acevedo Diaz, M.D Psychiatry · Gaithersburg, MD
- Kathryn J. Lucas, MD Endocrinology & Diabetes · Morehead City, NC
- Claire Presswood Internal Medicine · Morehead City, NC
- Michael A. Hassman, DO Family Medicine · Berlin, NJ
- Sridhar Guduri, M.D Allergy & Immunology · Dublin, OH
- Richard A. Mularski, MD, MCR, MSHS Pulmonology · Clackamas, OR
- Jerry L. Punch, MD Family Medicine · Knoxville, TN
- Samir T. Abdelshaheed, M.D. Family Medicine · Chesapeake, VA
- David S. Ramstad, MD, MPH Internal Medicine · Suffolk, VA
- Lisa A. Jackson, M.D. Preventive Medicine & Public Health · Seattle, WA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Cr Services Acquisition Us Llc $556,026
- Alliance for Multispecialty Research,llc $473,374
- Research Centers of America $315,326
- Cenexel Iresearch Llc $298,074
- Collaborative Neuroscience Research (cenexel Cns) $265,222
- Hassman Research Institute Llc $262,981
- Lucas Research, Inc $207,637
- Bb Holdings,llc Dba Jean Brown Research $183,521
- Group Health Cooperative $67,899
- Cbh Health Llc $56,286
- Research Centers of America,llc $49,648
- Emory University Hospital, GA $41,913
- Kaiser Foundation Hospital-Santa Clara, CA $31,109
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.