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A Study to Investigate Weight Management With LY3549492 Compared With Placebo in Adult Participants With Obesity or Overweight

Completed · Phase 2 · NCT06683508

Conditions: Obesity, Overweight

At a glance

Research payments reported, 2025
$9.7M
U.S. investigators named
54
Sites paid
57
Planned or actual enrollment
288

About the trial

Sponsor
Eli Lilly and Company
Tested
LY3549492 (drug), Placebo (drug)
Dates
Started 2024-11-13; completion 2026-05-04
Results posted
Not yet

The main purpose of this study, performed under the master protocol W8M-MC-CWMM (NCT06143956), is to evaluate the effects of LY3549492 in adults with obesity or overweight. Participation in the study will last about one year.

From ClinicalTrials.gov, last updated 2026-05-13. Full record, eligibility and contacts (opens in a new tab)

Industry funding

Eli Lilly and Company reported $9.7M in research payments for this study in 2025 (121 payments).

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • Monroe Biomedical Research $724,337
  • Headlands Horizons LLC $684,734
  • Lucas Research Inc $563,909
  • Great Lakes Clinical Trials $411,476
  • Indago Research & Health Center Inc $386,927
  • Sociedad Espanola De Medicina De La Adolescencia $381,225
  • Dent Neurosciences Research Center Inc $372,930
  • Charter Research LLC $348,627
  • Institute for Liver Health LLC $341,540
  • Peninsula Headlands LLC $330,536
  • Velocity Clinical Research Inc $329,519
  • Texas Valley Clinical Research LLC $310,249
  • Danville Orthopedic Clinic Inc $309,786
  • Tribe Clinical Research LLC $294,574
  • Suncoast Clinical Research $275,176
  • Medical Research PArtners $270,596
  • Lucida Clinical Trials $262,536
  • Clinvest Headlands LLC $260,307
  • Arcturus Healthcare PLC, Troy Internal $252,650
  • New Horizon Research Center $235,465
  • Central Washington Health Services $229,268
  • Ima Evaluations LLC DBA Ima Clinical Research $208,970
  • Endocrine Ips PLLC $198,745
  • Studymetrix Research LLC $192,330
  • Stamford Therapeutics Consortium $186,658
  • Las Vegas Medical Research LLC $178,053
  • Cotton Oneil Msd of Stormont Vail Healthcare $150,804
  • Norcal Medical Research Inc $148,181
  • Medication Management LLC $123,448
  • Cti Holdings Inc DBA Community Research Management Associates Inc $116,597
  • Rochester Clinical Research Inc $105,464
  • Ascension Medical Group $94,344
  • Northshore University Healthsystem - Evanston Hospital, IL $69,579
  • Future Search Trials of Dallas LP $68,123
  • Erg Holding Co LLC DBA St Louis Clinical Trials LLC $61,440
  • Iowa Diabetes and Endocrinology Rsrch Cntr $42,704
  • Louisville Metabolic $41,955
  • Diabetes and Endocrinology Consultants $16,881
  • Seen Medical of Ma PC DBA Knownwell $13,349
  • Cedars-Sinai Medical Center, CA $9,050
  • Lightship Inc $8,442
  • True North Med at N Suffolk Pplc $8,270
  • University at Buffalo $7,690
  • Wenatchee Valley Hospital $6,542
  • Clinvest Research LLC $6,516
  • Endeavor Clinical Trials PA $5,798
  • Medex Healthcare Research Inc $5,339
  • Futuresearch Trials of Neurology LP $5,160
  • Knownwell $4,223
  • North Suffolk Neurology $4,093
  • Palos Verdes Medical Group $4,049
  • Yshay Shlesinger MD $3,837
  • Northeast Research Institute $2,464
  • Tekton Research Inc $2,443
  • Hope Research Institute LLC $2,388
  • $735
  • Pharmquest Life Sciences LLC $5
  • Northshore University Healthsystem $4

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.