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Study of a 4-Dose Regimen of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From Approximately 2 Months of Age

Active, not recruiting · Phase 3 · NCT06736041

Conditions: Pneumococcal Immunization

At a glance

Research payments reported, 2025
$2.7M
U.S. investigators named
53
Sites paid
51
Planned or actual enrollment
1,714

About the trial

Sponsor
Sanofi Pasteur, a Sanofi Company
Tested
PCV21 vaccine (biological), Prevnar 20 vaccine (biological), M-M-R II vaccine (biological), RotaTeq (biological), Vaxelis vaccine (biological), Varivax (biological), Hexaxim Vaccine (biological)
Dates
Started 2024-12-18; completion 2027-05-17
Results posted
Not yet

This study is a Phase 3, randomized, modified double-blind study which aims to measure whether PCV21 vaccine (investigational pneumococcal conjugate vaccine) is safe and can help the body to develop germ-fighting agents called "antibodies" (immunogenicity) compared with 20-valent pneumococcal vaccine (Prevnar 20, licensed pneumococcal conjugate vaccine) when they are administered with routine pediatric vaccines in infants aged from approximately 2 months (42 to 89 days). The study duration per participant will be up to approximately 19 months. The study vaccines (either PCV21 or 20-valent pneumococcal vaccines) will be administered at approximately 2, 4, 6 and 12 to 15 months of age. Rout…

From ClinicalTrials.gov, last updated 2026-04-22. Full record, eligibility and contacts (opens in a new tab)

Industry funding

Sanofi Pasteur Inc. reported $2.7M in research payments for this study in 2025 (324 payments).

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • Matrix Clinical Research,inc $370,732
  • Bmh,inc $237,861
  • Clinical Research Puerto Rico,inc $189,100
  • Caribbean Medical Research Center Llc $140,149
  • Neutra Life Sciences Llc $116,825
  • Elba Antoinette Peres Vargas $116,185
  • Ponce School of Medicine Foundation, Inc $115,918
  • Community Clinical Research Network Inc $112,539
  • Medical Associates of Northwest Arkansas,pa $77,975
  • Physicians Administrative Solutions Llc $76,787
  • Chemidox Clinical Trials $76,140
  • Linq Research Llc $69,000
  • Sec Clinical Research LLC $57,394
  • Tribe Clinical Research Llc Mountain View Clinical Research $55,619
  • Michigan Institute of Research $53,789
  • Alliance for Multispecialty Research,llc $51,585
  • Rio Clinical Trials, Llc $50,520
  • Innovo Research Inc $49,871
  • Acevedo Clinical Research Associates Co $47,233
  • Leavitt Clinical Research Inc $44,981
  • Helios Cr, Inc $41,487
  • Caguas Clinical Research $41,072
  • Innovo Research Llc $35,206
  • Medical Research PArtners $32,613
  • Coastal Carolina Research Center,incorporation $30,972
  • Fomat Medical Research Inc $30,534
  • Clinical Research PArtners, Llc $28,978
  • Dade Research Center Llc $28,257
  • Emda Clinical Research $24,200
  • University of Missouri Health Care, MO $24,098
  • Square 1 Clinical Research Inc $22,936
  • Interspond Llc $22,417
  • National Clinical Trials Inc $21,689
  • Alliance for Multispecialty Research Llc $21,516
  • Velocity Clinical Research,inc $16,350
  • Prohealth Research Center Inc $15,597
  • Pasadena Clinical Trials $14,000
  • Houston Clinical Research Associates $14,000
  • Bioresearch PArtner Holdings Lllp $12,669
  • Tanner Memorial Clinic Tanner Clinic $12,373
  • South Texas Clinical Research $11,382
  • Snake River Research,pllc $10,393
  • Inquest Clinical Research, Llc $9,034
  • Riveldi Biomedical Research and Associates Miami Lakes $5,123
  • Keypoint Clinical Research Llc $5,048
  • Dfw Clinical Research $4,215
  • Biomedical Research,llc $3,987
  • Cotton Oneil Clinic Revocable Trust Cotton Oneil Clinical Research Center $3,518
  • Velocity Clinical Research $2,466
  • Monroe Biomedical Research Monroe $2,077
  • Javara Inc $750
  • $79

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.