A Long-Term Study of ALKS 2680 in Subjects With Narcolepsy and Idiopathic Hypersomnia
Recruiting · Phase 2, Phase 3 · NCT06767683
Conditions: Narcolepsy Type 1, Narcolepsy Type 2, Idiopathic Hypersomnia
At a glance
- Research payments reported, 2025
- $1.9M
- U.S. investigators named
- 36
- Sites paid
- 36
- Planned or actual enrollment
- 786
About the trial
- Sponsor
- Alkermes, Inc.
- Tested
- ALKS 2680, 4mg (drug), ALKS 2680, 6mg (drug), ALKS 2680, 8mg (drug), ALKS 2680, 10mg (drug), ALKS 2680, 14mg (drug), ALKS 2680, 18mg (drug)
- Dates
- Started 2025-01-27; completion 2030-06
- Results posted
- Not yet
The purpose of this study is to continue to measure the safety, tolerability, and durability of treatment effect in subjects with Narcolepsy Type 1 (NT1), Narcolepsy Type 2 (NT2), or Idiopathic Hypersomnia (IH) when taking ALKS 2680 tablets.
From ClinicalTrials.gov, last updated 2026-10-09. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Alkermes, Inc. reported $1.9M in research payments for this study in 2025 (1,017 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Paul E. Wylie, M.D. Psychiatry · Little Rock, AR
- Chad M. Ruoff, M.D. Sleep Medicine · Scottsdale, AZ
- Emmanuel J. Mignot, M.D Sleep Medicine · Stanford, CA
- Daniel Norman, M.D. Sleep Medicine · Los Angeles, CA
- Andrew O. Schreiber, MD Neurosurgery · Santa Ana, CA
- Stephen P. Duntley, MD Sleep Medicine · Aurora, CO
- Faisal A. Fakih, MD Specialist · Winter Park, FL
- Daniel G. Lorch, M.D. Pulmonology · Brandon, FL
- Edward Mezerhane, MD Sleep Medicine · Miami, FL
- Dragos G. Zanchi, M.D Pulmonology · Brandon, FL
- Dennis M. Lacey, MD Neurology · Atlanta, GA
- Phillip W. Nowlin, MD Family Medicine · Carrollton, GA
- Charles C. Wells, M.D. Sleep Medicine · Macon, GA
- Patrick E. Whitten, M.D. Pulmonology · Peoria, IL
- Damien R. Stevens, M.D. Pulmonology · Kansas City, KS
- James P. Maynard, M.D. Neurology · Fort Thomas, KY
- Vishal Saini, M.D. Sleep Medicine · Saginaw, MI
- Rahul B. Sangal, M.D. Sleep Medicine · Bloomfield Hills, MI
- Daniel T. Garber, M.D. Sleep Medicine · Concord, NC
- Andrew Krystal, M.D. Psychiatry · Durham, NC
- Thomas P. Stern, M.D. Pulmonology · Huntersville, NC
- Kevin J. Reichmuth, M.D. Pulmonology · Lincoln, NE
- Matthew J. Davis, MD Neurology · Middletown, NJ
- Alec B. Platt, M.D Pulmonology · Schenectody, NY
- Bruce C. Corser, MD Pulmonology · Cincinnati, OH
- Ryan S. Drake, DO Neurology · Canton, OH
- Nancy R. Foldvary-schaefer, DO Sleep Medicine · Cleveland, OH
- Asim Roy, M.D. Sleep Medicine · Dublin, OH
- John S. Khoury, M.D. Neurology · Abington, PA
- Richard K. Bogan, M.D. Pulmonology · Columbia, SC
- James M. Andry, MD Sleep Medicine · San Antonio, TX
- John D. Hudson, M.D. Sleep Medicine · Austin, TX
- Gerard J. Meskill, MD Sleep Medicine · Sugar Land, TX
- Henry S. Scheuller, M.D. Sleep Medicine · Jbsa Lackland, TX
- Jerald H. Simmons, MD Sleep Medicine · Houston, TX
- David T. Plante, MD Sleep Medicine · Madison, WI
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- The Board of Trustees of the Leland Stanford Junior University $224,372
- Clinical Neurophysiology Services PC $139,049
- Bogan Sleep Consultants, LLC $128,364
- Sleep Therapy & Research Center $90,924
- Teradan Clinical Trials $75,782
- Clinical Site PArtners, LLC. $72,081
- Mayo Clinic Hospital, AZ $69,759
- Neurotrials Research, Inc. $59,920
- Futuresearch Trials of Neurology, LLC. $58,835
- Tricoastal Narcolepsy and Sleep Disorders Center, PLLC. $57,546
- Sound Asleep Research, Inc. $53,995
- Sleep Practitioners, LLC $52,374
- Cleveland Clinic, OH $51,519
- The Board of Regents of the University of Wisconsin System $48,063
- Osf Heart of Mary Medical Center, IL $46,588
- Intrepid Research, LLC. $40,996
- University of Colorado Denver Hospital $40,859
- Bryan Medical Center, NE $38,853
- Neuroscience Research Center, LLC. $37,654
- Respiratory Specialists $37,300
- Clinical Research Institute $33,148
- Research Carolina Elite, LLC. $32,226
- University of Kansas Medical Center Research Institute, Inc. $32,187
- Comprehensive Sleep Medicine Associates Csma $31,128
- Pharmaseek, LLC. dba Wcg Site Network $30,866
- Community Research Management Associates, Inc. $30,776
- Preferred Research PArtners $30,069
- Advanced Respiratory and Sleep Medicine, PLLC $30,060
- Delta Waves Sleep Disorders and Research Center $28,504
- Pharmadev Clinical Research Institute, LLC $27,720
- Ohio Sleep Medicine and Neuroscience Institute $26,963
- Santa Monica Clinical Trials $25,431
- UCSF Langley Porter Psychiatric Hospital and Clinics, CA $17,692
- Sds Clinical Trials, Inc. $17,526
- Abington Neurological Associates, LTD. $17,298
- Patient First MD $17,298
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.