A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects With Idiopathic Hypersomnia
Active, not recruiting · Phase 2 · NCT06843590
Conditions: Idiopathic Hypersomnia
At a glance
- Research payments reported, 2025
- $2.1M
- U.S. investigators named
- 36
- Sites paid
- 36
- Planned or actual enrollment
- 126
About the trial
- Sponsor
- Alkermes, Inc.
- Tested
- ALKS 2680 (drug), Placebo (drug)
- Dates
- Started 2025-05-22; completion 2026-11
- Results posted
- Not yet
The purpose of this study is to measure the safety and decrease in daytime sleepiness in subjects with Idiopathic Hypersomnia when taking ALKS 2680 tablets compared with placebo tablets
From ClinicalTrials.gov, last updated 2026-09-25. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Alkermes, Inc. reported $2.1M in research payments for this study in 2025 (1,443 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Gordon S. Warner, MD Sleep Medicine · Cullman, AL
- Paul E. Wylie, M.D. Psychiatry · Little Rock, AR
- Chad M. Ruoff, M.D. Sleep Medicine · Scottsdale, AZ
- Emmanuel J. Mignot, M.D Sleep Medicine · Stanford, CA
- Daniel Norman, M.D. Sleep Medicine · Los Angeles, CA
- Andrew O. Schreiber, MD Neurosurgery · Santa Ana, CA
- Faisal A. Fakih, MD Specialist · Winter Park, FL
- Sergio Jaramillo, MD Sleep Medicine · Miami, FL
- Daniel G. Lorch, M.D. Pulmonology · Brandon, FL
- Edward Mezerhane, MD Sleep Medicine · Miami, FL
- Dragos G. Zanchi, M.D Pulmonology · Brandon, FL
- Dennis M. Lacey, MD Neurology · Atlanta, GA
- Phillip W. Nowlin, MD Family Medicine · Carrollton, GA
- Charles C. Wells, M.D. Sleep Medicine · Macon, GA
- Patrick E. Whitten, M.D. Pulmonology · Peoria, IL
- Damien R. Stevens, M.D. Pulmonology · Kansas City, KS
- Monica Makhija, M.D. Neurology · Worcester, MA
- Vishal Saini, M.D. Sleep Medicine · Saginaw, MI
- Daniel T. Garber, M.D. Sleep Medicine · Concord, NC
- Andrew Krystal, M.D. Psychiatry · Durham, NC
- Thomas P. Stern, M.D. Pulmonology · Huntersville, NC
- Kevin J. Reichmuth, M.D. Pulmonology · Lincoln, NE
- Matthew J. Davis, MD Neurology · Middletown, NJ
- Alec B. Platt, M.D Pulmonology · Schenectody, NY
- Bruce C. Corser, MD Pulmonology · Cincinnati, OH
- Ryan S. Drake, DO Neurology · Canton, OH
- Nancy R. Foldvary-schaefer, DO Sleep Medicine · Cleveland, OH
- Zhanna Fast, MD Internal Medicine · Philadelphia, PA
- Anne M. Morse, DO Child Neurology · Danville, PA
- Richard K. Bogan, M.D. Pulmonology · Columbia, SC
- James M. Andry, MD Sleep Medicine · San Antonio, TX
- John D. Hudson, M.D. Sleep Medicine · Austin, TX
- Gerard J. Meskill, MD Sleep Medicine · Sugar Land, TX
- Henry S. Scheuller, M.D. Sleep Medicine · Jbsa Lackland, TX
- Jerald H. Simmons, MD Sleep Medicine · Houston, TX
- David T. Plante, MD Sleep Medicine · Madison, WI
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Intrepid Research, LLC. $298,958
- Bogan Sleep Consultants, LLC $151,211
- Tricoastal Narcolepsy and Sleep Disorders Center, PLLC. $149,336
- The Board of Trustees of the Leland Stanford Junior University $137,978
- Mayo Clinic Hospital, AZ $133,114
- Teradan Clinical Trials $132,906
- UCSF Langley Porter Psychiatric Hospital and Clinics, CA $129,524
- Delta Waves Sleep Disorders and Research Center $114,660
- Sound Asleep Research, Inc. $113,202
- Advanced Respiratory and Sleep Medicine, PLLC $99,364
- The Board of Regents of the University of Wisconsin System $80,252
- Clinical Site PArtners, LLC. $73,156
- Sleep Practitioners, LLC $71,365
- Clinical Research Institute $58,265
- Pharmadev Clinical Research Institute, LLC $56,225
- Pharmaseek, LLC. dba Wcg Site Network $41,450
- Respiratory Specialists $34,982
- Bryan Medical Center, NE $30,390
- Thomas Jefferson University $28,969
- Cleveland Clinic, OH $28,869
- Osf Heart of Mary Medical Center, IL $22,935
- Preferred Research PArtners $22,584
- Neurotrials Research, Inc. $19,573
- Cullman Clinical Trials, LLC. $18,497
- Sleep Therapy & Research Center $17,471
- Neuroscience Research Center, LLC. $13,618
- Research Carolina Elite, LLC. $9,585
- Santa Monica Clinical Trials $7,305
- Futuresearch Trials of Neurology, LLC. $6,937
- Beth Israel Deaconess Medical Center, MA $6,551
- Patient First MD $4,385
- Serenity Research Center, LLC. $4,309
- Comprehensive Sleep Medicine Associates Csma $2,739
- University of Kansas Medical Center Research Institute, Inc. $2,739
- Geisinger Clinic $2,739
- Sds Clinical Trials, Inc. $2,587
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.